HsaEX6065111 @ hg38
Exon Skipping
Gene
ENSG00000126838 | PZP
Description
PZP, alpha-2-macroglobulin like [Source:HGNC Symbol;Acc:HGNC:9750]
Coordinates
chr12:9154616-9160025:-
Coord C1 exon
chr12:9159938-9160025
Coord A exon
chr12:9157175-9157355
Coord C2 exon
chr12:9154616-9154839
Length
181 bp
Sequences
Splice sites
3' ss Seq
ACCACATTTTGCCTTTACAGAAC
3' ss Score
10.47
5' ss Seq
AAGGTGAGA
5' ss Score
8.68
Exon sequences
Seq C1 exon
GTTACCAGAGACAGCTGAACTACAAACACCAAGATGGCTCCTACAGCACCTTTGGGGAACGATATGGCAGGAACCAGGGCAACACTTG
Seq A exon
AACCCTATTGTTCGCAATGCCCTGTTCTGCCTGGAGTCAGCCTGGAATGTAGCAAAGGAGGGGACCCATGGGAGCCATGTCTACACCAAGGCATTGCTGGCCTATGCTTTTTCCCTACTGGGAAAGCAAAATCAGAATAGAGAAATACTGAACTCACTTGATAAGGAAGCTGTGAAAGAAG
Seq C2 exon
ACAACCTCGTCCATTGGGAGCGCCCTCAGAGACCCAAGGCACCAGTGGGGCATCTTTACCAAACCCAGGCTCCCTCTGCTGAGGTGGAGATGACATCCTATGTGCTCCTCGCTTATCTCACGGCCCAGCCAGCCCCCACCTCAGGGGACCTGACCTCTGCAACTAACATTGTGAAGTGGATCATGAAGCAGCAGAACGCCCAAGGTGGTTTCTCCTCCACCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000126838_MULTIEX1-3/3=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.033 A=0.049 C2=0.227
Domain overlap (PFAM):
C1:
PF076789=A2M_comp=FE(11.3=100)
A:
PF076789=A2M_comp=FE(23.3=100)
C2:
PF076789=A2M_comp=FE(28.8=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCTACAGCACCTTTGGGGAA
R:
GGCGTTCTGCTGCTTCATGAT
Band lengths:
250-431
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains