HsaEX6076336 @ hg38
Exon Skipping
Gene
ENSG00000140545 | MFGE8
Description
milk fat globule-EGF factor 8 protein [Source:HGNC Symbol;Acc:HGNC:7036]
Coordinates
chr15:88901551-88906778:-
Coord C1 exon
chr15:88906626-88906778
Coord A exon
chr15:88905757-88905901
Coord C2 exon
chr15:88901551-88901735
Length
145 bp
Sequences
Splice sites
3' ss Seq
TCTTGTCCCTTCCCTGCTAGGAG
3' ss Score
9.43
5' ss Seq
ACGGTGAGT
5' ss Score
11.45
Exon sequences
Seq C1 exon
GTGAACCTGCTGCGGAGGATGTGGGTAACAGGTGTGGTGACGCAGGGTGCCAGCCGCTTGGCCAGTCATGAGTACCTGAAGGCCTTCAAGGTGGCCTACAGCCTTAATGGACACGAATTCGATTTCATCCATGATGTTAATAAAAAACACAAG
Seq A exon
GAGTTTGTGGGTAACTGGAACAAAAACGCGGTGCATGTCAACCTGTTTGAGACCCCTGTGGAGGCTCAGTACGTGAGATTGTACCCCACGAGCTGCCACACGGCCTGCACTCTGCGCTTTGAGCTACTGGGCTGTGAGCTGAACG
Seq C2 exon
GATGCGCCAATCCCCTGGGCCTGAAGAATAACAGCATCCCTGACAAGCAGATCACGGCCTCCAGCAGCTACAAGACCTGGGGCTTGCATCTCTTCAGCTGGAACCCCTCCTATGCACGGCTGGACAAGCAGGGCAACTTCAACGCCTGGGTTGCGGGGAGCTACGGTAACGATCAGTGGCTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000140545_MULTIEX3-1/4=C1-C2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.009
Domain overlap (PFAM):
C1:
PF0075420=F5_F8_type_C=PU(18.9=83.3)
A:
PF0075420=F5_F8_type_C=PD(29.7=83.7)
C2:
PF0075420=F5_F8_type_C=PU(32.1=72.6)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTGGGTAACAGGTGTGGTGAC
R:
GAGGGGTTCCAGCTGAAGAGA
Band lengths:
242-387
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains