HsaEX6085991 @ hg19
Exon Skipping
Gene
ENSG00000138735 | PDE5A
Description
phosphodiesterase 5A, cGMP-specific [Source:HGNC Symbol;Acc:8784]
Coordinates
chr4:120481451-120486565:-
Coord C1 exon
chr4:120486476-120486565
Coord A exon
chr4:120483988-120484125
Coord C2 exon
chr4:120481451-120481518
Length
138 bp
Sequences
Splice sites
3' ss Seq
CTCCTAATTTTTTTGTCTAGGTG
3' ss Score
9.6
5' ss Seq
TCCGTGAGT
5' ss Score
8.93
Exon sequences
Seq C1 exon
GACTTTGCTGCTTATTTGGCATTTTGTGGTATTGTTCTTCATAATGCTCAGCTCTATGAGACTTCACTGCTGGAGAACAAGAGAAATCAG
Seq A exon
GTGCTGCTTGACCTTGCTAGTTTAATTTTTGAAGAACAACAATCATTAGAAGTAATTTTGAAGAAAATAGCTGCCACTATTATCTCTTTCATGCAAGTGCAGAAATGCACCATTTTCATAGTGGATGAAGATTGCTCC
Seq C2 exon
GATTCTTTTTCTAGTGTGTTTCACATGGAGTGTGAGGAATTAGAAAAATCATCTGATACATTAACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138735-'8-11,'8-10,9-11=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.043
Domain overlap (PFAM):
C1:
PF0159021=GAF=PD(7.9=40.0)
A:
PF0159021=GAF=PU(19.6=67.4)
C2:
PF0159021=GAF=FE(13.9=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACTTTGCTGCTTATTTGGCA
R:
TTTTTCTAATTCCTCACACTCCATGT
Band lengths:
138-276
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)