HsaEX6091369 @ hg19
Exon Skipping
Gene
ENSG00000185198 | PRSSL1
Description
protease, serine, 57 [Source:HGNC Symbol;Acc:31397]
Coordinates
chr19:691858-695483:-
Coord C1 exon
chr19:695352-695483
Coord A exon
chr19:694814-694970
Coord C2 exon
chr19:691858-692002
Length
157 bp
Sequences
Splice sites
3' ss Seq
GACTCAGGCCGTCCCTCCAGCAG
3' ss Score
3.75
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
Exon sequences
Seq C1 exon
GTGGGAGCCACGGCCCGAAGACCTCTGCGGGGAGACGCCAGCCTGCGTCTGCCATGGGGCTCGGGTTGAGGGGCTGGGGACGTCCTCTGCTGACTGTGGCCACCGCCCTGATGCTGCCCGTGAAGCCCCCCG
Seq A exon
CAGGCTCCTGGGGGGCCCAGATCATCGGGGGCCACGAGGTGACCCCCCACTCCAGGCCCTACATGGCATCCGTGCGCTTCGGGGGCCAACATCACTGCGGAGGCTTCCTGCTGCGAGCCCGCTGGGTGGTCTCGGCCGCCCACTGCTTCAGCCACAG
Seq C2 exon
AGACCTCCGCACTGGCCTGGTGGTGCTGGGCGCCCACGTCCTGAGTACTGCGGAGCCCACCCAGCAGGTGTTTGGCATCGATGCTCTCACCACACACCCCGACTACCACCCCATGACCCACGCCAACGACATCTGCCTGCTGCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185198-'0-2,'0-0,1-2=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0008921=Trypsin=PU(20.0=84.9)
C2:
PF0008921=Trypsin=FE(21.3=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGACCTCTGCGGGGAGAC
R:
CAGCAGGCAGATGTCGTTGG
Band lengths:
258-415
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)