HsaEX6091369 @ hg38
Exon Skipping
Gene
ENSG00000185198 | PRSS57
Description
protease, serine 57 [Source:HGNC Symbol;Acc:HGNC:31397]
Coordinates
chr19:691858-695498:-
Coord C1 exon
chr19:695352-695498
Coord A exon
chr19:694814-694967
Coord C2 exon
chr19:691858-692002
Length
154 bp
Sequences
Splice sites
3' ss Seq
TCAGGCCGTCCCTCCAGCAGGCT
3' ss Score
5.03
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
Exon sequences
Seq C1 exon
GGCCGTTGGCTGAGGGTGGGAGCCACGGCCCGAAGACCTCTGCGGGGAGACGCCAGCCTGCGTCTGCCATGGGGCTCGGGTTGAGGGGCTGGGGACGTCCTCTGCTGACTGTGGCCACCGCCCTGATGCTGCCCGTGAAGCCCCCCG
Seq A exon
GCTCCTGGGGGGCCCAGATCATCGGGGGCCACGAGGTGACCCCCCACTCCAGGCCCTACATGGCATCCGTGCGCTTCGGGGGCCAACATCACTGCGGAGGCTTCCTGCTGCGAGCCCGCTGGGTGGTCTCGGCCGCCCACTGCTTCAGCCACAG
Seq C2 exon
AGACCTCCGCACTGGCCTGGTGGTGCTGGGCGCCCACGTCCTGAGTACTGCGGAGCCCACCCAGCAGGTGTTTGGCATCGATGCTCTCACCACACACCCCGACTACCACCCCATGACCCACGCCAACGACATCTGCCTGCTGCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185198-'0-5,'0-3,1-5=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.029 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0008921=Trypsin=PU(20.0=86.5)
C2:
PF0008921=Trypsin=FE(21.3=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAAGACCTCTGCGGGGAGAC
R:
CAGCAGGCAGATGTCGTTGG
Band lengths:
258-412
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains