HsaEX6091403 @ hg19
Exon Skipping
Gene
ENSG00000175221 | MED16
Description
mediator complex subunit 16 [Source:HGNC Symbol;Acc:17556]
Coordinates
chr19:876974-881714:-
Coord C1 exon
chr19:881559-881714
Coord A exon
chr19:879937-880148
Coord C2 exon
chr19:876974-877180
Length
212 bp
Sequences
Splice sites
3' ss Seq
GCAGTGCCTGTGCCCCACAGGGC
3' ss Score
7.22
5' ss Seq
AAGGTGAGC
5' ss Score
9.6
Exon sequences
Seq C1 exon
TTGGCGACAAACAGCCCACAATTCTCAAATGGCGGATCCTATCGGCCACCAACGATCTGGACCGTGTGTCGGCCGTGGCGCTGCCCAAGCTGCCCATCTCGCTCACCAACACCGACCTCAAGGTGGCCAGCGACACACAGTTCTACCCTGGCCTCG
Seq A exon
GGCTGGCCCTGGCCTTCCACGACGGCAGCGTCCACATCGTGCACCGGCTCTCACTGCAGACCATGGCCGTCTTCTACAGCTCCGCGGCCCCGAGGCCTGTGGATGAGCCGGCCATGAAGCGCCCCCGCACCGCGGGCCCCGCCGTCCACTTAAAGGCTATGCAGCTATCGTGGACGTCACTGGCCCTGGTGGGGATTGACAGCCACGGGAAG
Seq C2 exon
CTGAGCGTGCTCCGCCTCTCACCTTCCATGGGCCACCCGCTGGAGGTGGGGCTGGCGCTGCGGCACCTGCTCTTCCTGCTGGAGTACTGCATGGTGACCGGCTACGACTGGTGGGACATCCTGCTGCACGTGCAGCCCAGTATGGTACAGAGCCTGGTGGAGAAGCTGCACGAGGAGTACACGCGCCAGACCGCTGCCCTGCAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175221-'8-9,'8-8,9-9=AN
Average complexity
A_S
Mappability confidence:
88%=100=75%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.127 C2=0.000
Domain overlap (PFAM):
C1:
PF116353=Med16=FE(16.5=100)
A:
PF116353=Med16=FE(20.8=100),PF116353=Med16=PU(2.2=2.8)
C2:
PF116353=Med16=FE(12.8=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTATCGGCCACCAACGATCTG
R:
GTGTACTCCTCGTGCAGCTTC
Band lengths:
300-512
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)