HsaEX6091403 @ hg38
Exon Skipping
Gene
ENSG00000175221 | MED16
Description
mediator complex subunit 16 [Source:HGNC Symbol;Acc:HGNC:17556]
Coordinates
chr19:875244-881714:-
Coord C1 exon
chr19:881559-881714
Coord A exon
chr19:879937-880148
Coord C2 exon
chr19:875244-875454
Length
212 bp
Sequences
Splice sites
3' ss Seq
GCAGTGCCTGTGCCCCACAGGGC
3' ss Score
7.22
5' ss Seq
AAGGTGAGC
5' ss Score
9.6
Exon sequences
Seq C1 exon
TTGGCGACAAACAGCCCACAATTCTCAAATGGCGGATCCTATCGGCCACCAACGATCTGGACCGTGTGTCGGCCGTGGCGCTGCCCAAGCTGCCCATCTCGCTCACCAACACCGACCTCAAGGTGGCCAGCGACACACAGTTCTACCCTGGCCTCG
Seq A exon
GGCTGGCCCTGGCCTTCCACGACGGCAGCGTCCACATCGTGCACCGGCTCTCACTGCAGACCATGGCCGTCTTCTACAGCTCCGCGGCCCCGAGGCCTGTGGATGAGCCGGCCATGAAGCGCCCCCGCACCGCGGGCCCCGCCGTCCACTTAAAGGCTATGCAGCTATCGTGGACGTCACTGGCCCTGGTGGGGATTGACAGCCACGGGAAG
Seq C2 exon
GTCCTCTCCACCCGGATCCTGGCCATGAAGGCCTCGCTCTGCAAGCTGTCGCCCTGCACGGTGACCCGCGTGTGCGACTACCACACCAAGCTCTTCCTCATCGCCATCAGCTCCACCCTGAAGTCGCTGCTGCGCCCCCACTTTCTCAACACGCCTGACAAGAGCCCCGGCGACCGGCTGACCGAGATCTGCACCAAGATCACCGACGTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175221_MULTIEX1-8/15=7-10
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.007 A=0.132 C2=0.014
Domain overlap (PFAM):
C1:
PF116353=Med16=FE(12.9=100)
A:
PF116353=Med16=FE(20.8=100),PF116353=Med16=PU(2.2=2.8)
C2:
PF116353=Med16=PD(0.9=4.2),PF116353=Med16=FE(78.7=100)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAACGATCTGGACCGTGTGTC
R:
TCTTGGTGCAGATCTCGGTCA
Band lengths:
306-518
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains