HsaEX6091402 @ hg38
Exon Skipping
Gene
ENSG00000175221 | MED16
Description
mediator complex subunit 16 [Source:HGNC Symbol;Acc:HGNC:17556]
Coordinates
chr19:875244-893218:-
Coord C1 exon
chr19:893086-893218
Coord A exon
chr19:884903-885008
Coord C2 exon
chr19:875244-875454
Length
106 bp
Sequences
Splice sites
3' ss Seq
CACCCCCACCTCCCCCGCAGGTG
3' ss Score
11.41
5' ss Seq
TGGGTGAGT
5' ss Score
8.73
Exon sequences
Seq C1 exon
CAGAAGTCTTTGGGAGGCGGCCCCACGCCTCAGGCGACTGGTTGTTACCGAGGAAGATGGCGGCGCCAGACCCGAGGCGCTAGGGAAGATCGCACCGCGGACGCCCGCTGAGCTTGGCGCACGGGCCGACCAG
Seq A exon
GTGCTTTTGTGCGCGTCCAGCCAGACCAGCAGCATCGTGGAGTGCTGGTCCCTGCGCAAGGAGGGACTCCCCGTGAACAACATCTTCCAGCAGATCTCCCCCGTGG
Seq C2 exon
GTCCTCTCCACCCGGATCCTGGCCATGAAGGCCTCGCTCTGCAAGCTGTCGCCCTGCACGGTGACCCGCGTGTGCGACTACCACACCAAGCTCTTCCTCATCGCCATCAGCTCCACCCTGAAGTCGCTGCTGCGCCCCCACTTTCTCAACACGCCTGACAAGAGCCCCGGCGACCGGCTGACCGAGATCTGCACCAAGATCACCGACGTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175221_MULTIEX1-6/15=C1-10
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.000 C2=0.014
Domain overlap (PFAM):
C1:
NA
A:
PF116353=Med16=FE(16.5=100)
C2:
PF116353=Med16=PD(0.9=4.2),PF116353=Med16=FE(78.7=100)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGTTACCGAGGAAGATGGCG
R:
TCAGGCGTGTTGAGAAAGTGG
Band lengths:
250-356
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains