HsaEX0038604 @ hg38
Exon Skipping
Gene
ENSG00000175221 | MED16
Description
mediator complex subunit 16 [Source:HGNC Symbol;Acc:HGNC:17556]
Coordinates
chr19:875244-880148:-
Coord C1 exon
chr19:879937-880148
Coord A exon
chr19:876974-877180
Coord C2 exon
chr19:875244-875454
Length
207 bp
Sequences
Splice sites
3' ss Seq
TTGGGCTCTGTCTCTGGCAGCTG
3' ss Score
8.63
5' ss Seq
CAGGTGGGG
5' ss Score
6.92
Exon sequences
Seq C1 exon
GGCTGGCCCTGGCCTTCCACGACGGCAGCGTCCACATCGTGCACCGGCTCTCACTGCAGACCATGGCCGTCTTCTACAGCTCCGCGGCCCCGAGGCCTGTGGATGAGCCGGCCATGAAGCGCCCCCGCACCGCGGGCCCCGCCGTCCACTTAAAGGCTATGCAGCTATCGTGGACGTCACTGGCCCTGGTGGGGATTGACAGCCACGGGAAG
Seq A exon
CTGAGCGTGCTCCGCCTCTCACCTTCCATGGGCCACCCGCTGGAGGTGGGGCTGGCGCTGCGGCACCTGCTCTTCCTGCTGGAGTACTGCATGGTGACCGGCTACGACTGGTGGGACATCCTGCTGCACGTGCAGCCCAGTATGGTACAGAGCCTGGTGGAGAAGCTGCACGAGGAGTACACGCGCCAGACCGCTGCCCTGCAGCAG
Seq C2 exon
GTCCTCTCCACCCGGATCCTGGCCATGAAGGCCTCGCTCTGCAAGCTGTCGCCCTGCACGGTGACCCGCGTGTGCGACTACCACACCAAGCTCTTCCTCATCGCCATCAGCTCCACCCTGAAGTCGCTGCTGCGCCCCCACTTTCTCAACACGCCTGACAAGAGCCCCGGCGACCGGCTGACCGAGATCTGCACCAAGATCACCGACGTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175221-'21-34,'21-27,24-34
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.132 A=0.011 C2=0.014
Domain overlap (PFAM):
C1:
PF116353=Med16=FE(20.8=100),PF116353=Med16=PU(2.2=2.8)
A:
PF116353=Med16=FE(16.9=100)
C2:
PF116353=Med16=PD(0.9=4.2),PF116353=Med16=FE(78.7=100)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CATGGCCGTCTTCTACAGCTC
R:
CAGGCGTGTTGAGAAAGTGGG
Band lengths:
308-515
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development