HsaEX6091456 @ hg38
Exon Skipping
Gene
ENSG00000180448 | ARHGAP45
Description
Rho GTPase activating protein 45 [Source:HGNC Symbol;Acc:HGNC:17102]
Coordinates
chr19:1082840-1084346:+
Coord C1 exon
chr19:1082840-1083066
Coord A exon
chr19:1083143-1083353
Coord C2 exon
chr19:1084238-1084346
Length
211 bp
Sequences
Splice sites
3' ss Seq
GGCCCCTGCCCACCCCGCAGGAT
3' ss Score
8.16
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
Exon sequences
Seq C1 exon
CTTCCCGAGCCGCTCATCTCCTTCCGCCTCTACCACGAGCTCGTAGGGCTGGCCAAGGACAGCCTGAAGGCAGAGGCCGAGGCCAAGGCGGCGTCCCGGGGCCGGCAGGACGGCTCGGAGAGCGAGGCAGTGGCGGTGGCCCTGGCAGGTCGGCTGCGGGAGCTCCTGCGGGACCTGCCGCCTGAGAACCGGGCCTCGCTGCAGTACCTGCTGCGTCACCTACGCAG
Seq A exon
GATCGTGGAGGTGGAGCAGGACAACAAGATGACCCCCGGGAACCTGGGCATCGTGTTCGGGCCCACGCTGCTTCGGCCACGGCCCACCGAGGCCACCGTGTCCCTCTCCTCCCTGGTGGATTATCCCCATCAGGCCCGCGTCATCGAGACTCTCATCGTCCACTACGGCCTGGTCTTCGAGGAGGAGCCGGAGGAGACCCCCGGGGGCCAG
Seq C2 exon
GACGAGTCATCCAACCAGCGAGCTGAGGTAGTCGTCCAGGTGCCGTACCTGGAGGCGGGCGAGGCGGTGGTCTACCCGCTGCAGGAGGCGGCGGCGGACGGGTGCAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000180448-'46-58,'46-56,48-58
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.148 A=0.226 C2=0.509
Domain overlap (PFAM):
C1:
PF0062022=RhoGAP=FE(43.4=100)
A:
PF0062022=RhoGAP=PD(18.5=45.1)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CATCTCCTTCCGCCTCTACCA
R:
TCCTGCAGCGGGTAGACC
Band lengths:
299-510
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains