HsaEX6092304 @ hg38
Exon Skipping
Gene
ENSG00000125730 | C3
Description
complement C3 [Source:HGNC Symbol;Acc:HGNC:1318]
Coordinates
chr19:6696379-6697556:-
Coord C1 exon
chr19:6697344-6697556
Coord A exon
chr19:6696593-6696659
Coord C2 exon
chr19:6696379-6696465
Length
67 bp
Sequences
Splice sites
3' ss Seq
CCACCTCTAACACTGCGTAGCCG
3' ss Score
3.58
5' ss Seq
GTGGTGAGT
5' ss Score
8.95
Exon sequences
Seq C1 exon
GTGAGGGTGGAACTACTCCACAATCCAGCCTTCTGCAGCCTGGCCACCACCAAGAGGCGTCACCAGCAGACCGTAACCATCCCCCCCAAGTCCTCGTTGTCCGTTCCATATGTCATCGTGCCGCTAAAGACCGGCCTGCAGGAAGTGGAAGTCAAGGCTGCTGTCTACCATCATTTCATCAGTGACGGTGTCAGGAAGTCCCTGAAGGTCGTG
Seq A exon
CCGGAAGGAATCAGAATGAACAAAACTGTGGCTGTTCGCACCCTGGATCCAGAACGCCTGGGCCGTG
Seq C2 exon
AAGGAGTGCAGAAAGAGGACATCCCACCTGCAGACCTCAGTGACCAAGTCCCGGACACCGAGTCTGAGACCAGAATTCTCCTGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125730-'46-62,'46-61,49-62
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.085 A=0.348 C2=0.867
Domain overlap (PFAM):
C1:
PF0020717=A2M=PD(4.1=5.6)
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTCATCGTGCCGCTAAAGAC
R:
TCTGGTCTCAGACTCGGTGTC
Band lengths:
177-244
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains