HsaEX6092308 @ hg38
Exon Skipping
Gene
ENSG00000125730 | C3
Description
complement C3 [Source:HGNC Symbol;Acc:HGNC:1318]
Coordinates
chr19:6680158-6686902:-
Coord C1 exon
chr19:6686746-6686902
Coord A exon
chr19:6686124-6686287
Coord C2 exon
chr19:6680158-6680263
Length
164 bp
Sequences
Splice sites
3' ss Seq
ATGGGGTATCTTCTTTGCAGATA
3' ss Score
8.7
5' ss Seq
CAGGCAAGT
5' ss Score
3.1
Exon sequences
Seq C1 exon
AGCCTGCCAGGCAGCATCACTAAAGCAGGAGACTTCCTTGAAGCCAACTACATGAACCTACAGAGATCCTACACTGTGGCCATTGCTGGCTATGCTCTGGCCCAGATGGGCAGGCTGAAGGGGCCTCTTCTTAACAAATTTCTGACCACAGCCAAAG
Seq A exon
ATAAGAACCGCTGGGAGGACCCTGGTAAGCAGCTCTACAACGTGGAGGCCACATCCTATGCCCTCTTGGCCCTACTGCAGCTAAAAGACTTTGACTTTGTGCCTCCCGTCGTGCGTTGGCTCAATGAACAGAGATACTACGGTGGTGGCTATGGCTCTACCCAG
Seq C2 exon
GTCTCACACTCTGAGGATGACTGTCTAGCTTTCAAAGTTCACCAATACTTTAATGTAGAGCTTATCCAGCCTGGAGCAGTCAAGGTCTACGCCTATTACAACCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125730_MULTIEX1-1/13=C1-9
Average complexity
C2*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF076789=A2M_comp=FE(22.2=100)
A:
PF076789=A2M_comp=FE(23.1=100)
C2:
PF076779=A2M_recep=FE(36.5=100)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAGGCAGCATCACTAAAGCA
R:
TAGGCGTAGACCTTGACTGCT
Band lengths:
246-410
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains