HsaEX6092309 @ hg19
Exon Skipping
Gene
ENSG00000125730 | C3
Description
complement component 3 [Source:HGNC Symbol;Acc:1318]
Coordinates
chr19:6684786-6686298:-
Coord C1 exon
chr19:6686135-6686298
Coord A exon
chr19:6684999-6685157
Coord C2 exon
chr19:6684786-6684845
Length
159 bp
Sequences
Splice sites
3' ss Seq
TTCTCTCTTGTGGGTTCTAGGCC
3' ss Score
9.71
5' ss Seq
GAGGTACAG
5' ss Score
6.62
Exon sequences
Seq C1 exon
ATAAGAACCGCTGGGAGGACCCTGGTAAGCAGCTCTACAACGTGGAGGCCACATCCTATGCCCTCTTGGCCCTACTGCAGCTAAAAGACTTTGACTTTGTGCCTCCCGTCGTGCGTTGGCTCAATGAACAGAGATACTACGGTGGTGGCTATGGCTCTACCCAG
Seq A exon
GCCACCTTCATGGTGTTCCAAGCCTTGGCTCAATACCAAAAGGACGCCCCTGACCACCAGGAACTGAACCTTGATGTGTCCCTCCAACTGCCCAGCCGCAGCTCCAAGATCACCCACCGTATCCACTGGGAATCTGCCAGCCTCCTGCGATCAGAAGAG
Seq C2 exon
ACCAAGGAAAATGAGGGTTTCACAGTCACAGCTGAAGGAAAAGGCCAAGGCACCTTGTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125730-'44-45,'44-44,45-45=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.113 C2=0.425
Domain overlap (PFAM):
C1:
PF076789=A2M_comp=FE(23.1=100)
A:
PF076789=A2M_comp=PD(5.6=24.5)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATAAGAACCGCTGGGAGGACC
R:
GGTGCCTTGGCCTTTTCCTTC
Band lengths:
218-377
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)