HsaEX6092309 @ hg38
Exon Skipping
Gene
ENSG00000125730 | C3
Description
complement C3 [Source:HGNC Symbol;Acc:HGNC:1318]
Coordinates
chr19:6677704-6686287:-
Coord C1 exon
chr19:6686124-6686287
Coord A exon
chr19:6684988-6685146
Coord C2 exon
chr19:6677704-6678023
Length
159 bp
Sequences
Splice sites
3' ss Seq
TTCTCTCTTGTGGGTTCTAGGCC
3' ss Score
9.71
5' ss Seq
GAGGTACAG
5' ss Score
6.62
Exon sequences
Seq C1 exon
ATAAGAACCGCTGGGAGGACCCTGGTAAGCAGCTCTACAACGTGGAGGCCACATCCTATGCCCTCTTGGCCCTACTGCAGCTAAAAGACTTTGACTTTGTGCCTCCCGTCGTGCGTTGGCTCAATGAACAGAGATACTACGGTGGTGGCTATGGCTCTACCCAG
Seq A exon
GCCACCTTCATGGTGTTCCAAGCCTTGGCTCAATACCAAAAGGACGCCCCTGACCACCAGGAACTGAACCTTGATGTGTCCCTCCAACTGCCCAGCCGCAGCTCCAAGATCACCCACCGTATCCACTGGGAATCTGCCAGCCTCCTGCGATCAGAAGAG
Seq C2 exon
CCTCAGCTACATCATCGGGAAGGACACTTGGGTGGAGCACTGGCCCGAGGAGGACGAATGCCAAGACGAAGAGAACCAGAAACAATGCCAGGACCTCGGCGCCTTCACCGAGAGCATGGTTGTCTTTGGGTGCCCCAACTGACCACACCCCCATTCCCCCACTCCAGATAAAGCTTCAGTTATATCTCACGTGTCTGGAGTTCTTTGCCAAGAGGGAGAGGCTGAAATCCCCAGCCGCCTCACCTGCAGCTCAGCTCCATCCTACTTGAAACCTCACCTGTTCCCACCGCATTTTCTCCTGGCGTTCGCCTGCTAGTGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125730_MULTIEX1-2/13=1-C2
Average complexity
C2*
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.113 C2=0.234
Domain overlap (PFAM):
C1:
PF076789=A2M_comp=FE(23.1=100)
A:
PF076789=A2M_comp=PD(5.6=24.5)
C2:
PF0175916=NTR=PD(24.3=56.2)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGACCCTGGTAAGCAGCTCTA
R:
GGTCCTGGCATTGTTTCTGGT
Band lengths:
243-402
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains