HsaEX6093469 @ hg38
Exon Skipping
Gene
ENSG00000123143 | PKN1
Description
protein kinase N1 [Source:HGNC Symbol;Acc:HGNC:9405]
Coordinates
chr19:14467718-14471859:+
Coord C1 exon
chr19:14467718-14467793
Coord A exon
chr19:14467876-14467967
Coord C2 exon
chr19:14471581-14471859
Length
92 bp
Sequences
Splice sites
3' ss Seq
CCTGCCCACTGTGGTTCCAGGTG
3' ss Score
9.44
5' ss Seq
GAGGTGGGG
5' ss Score
4.41
Exon sequences
Seq C1 exon
CCCTCTGAGGAAGTCACCTCTGACCCTCGAAGATTTCAAGTTCCTGGCGGTGCTGGGCCGGGGTCATTTTGGGAAG
Seq A exon
GTGCTCCTCTCCGAATTCCGGCCCAGTGGGGAGCTGTTCGCCATCAAGGCTCTGAAGAAAGGGGACATTGTGGCCCGAGACGAGGTGGAGAG
Seq C2 exon
ACTCTGGGCTGGGAAGCCCTGTTGGCCCGGCGCCTGCCACCGCCCTTTGTGCCCACGCTGTCCGGCCGCACCGACGTCAGCAACTTCGACGAGGAGTTCACCGGGGAGGCCCCCACACTGAGCCCGCCCCGCGACGCGCGGCCCCTCACAGCCGCGGAGCAGGCAGCCTTCCTGGACTTCGACTTCGTGGCCGGGGGCTGCTAGCCCCCTCCCCTGCCCCTGCCCCTGCCCCTGCCCGAGAGCTCTTAGTTTTTAAAAAGGCCTTTGGGATTTGCCGGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123143_MULTIEX1-2/9=1-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.051 A=0.000 C2=0.477
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=PU(5.0=50.0)
A:
PF0006920=Pkinase=FE(11.5=100)
C2:
PF0043319=Pkinase_C=WD(100=69.1)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTCACCTCTGACCCTCGAAGA
R:
CGGTGAACTCCTCGTCGAAGT
Band lengths:
167-259
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains