HsaEX7000643 @ hg38
Exon Skipping
Gene
ENSG00000197959 | DNM3
Description
dynamin 3 [Source:HGNC Symbol;Acc:HGNC:29125]
Coordinates
chr1:172379018-172388809:+
Coord C1 exon
chr1:172379018-172379182
Coord A exon
chr1:172387133-172387359
Coord C2 exon
chr1:172388573-172388809
Length
227 bp
Sequences
Splice sites
3' ss Seq
TCTCTGTGGTGATCTGACAGGTT
3' ss Score
7.61
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
Exon sequences
Seq C1 exon
GCTGAAAATGATGAGAATGGACAAGCAGAAAACTTTTCCATGGACCCACAATTGGAGAGGCAAGTGGAGACCATTCGCAACCTCGTAGACTCCTACATGTCCATTATCAACAAATGTATCCGAGATCTAATTCCAAAAACAATAATGCACCTTATGATCAATAAC
Seq A exon
GTTAAAGATTTCATAAATTCCGAGCTCCTAGCACAGTTGTATTCTTCAGAGGACCAAAATACCCTGATGGAGGAATCTGCTGAGCAGGCTCAGCGCCGGGATGAGATGCTTCGAATGTATCAAGCACTGAAAGAAGCCCTTGGGATAATTGGGGACATCAGCACAGCCACCGTGTCCACTCCGGCACCCCCTCCAGTGGATGACTCCTGGATACAGCACTCTCGCAG
Seq C2 exon
GTCACCTCCTCCAAGCCCCACAACCCAAAGGAGGCCAACACTAAGTGCTCCCCTCGCAAGGCCCACATCCGGCCGAGGACCAGCTCCTGCCATTCCCTCTCCTGGCCCCCACTCTGGGGCTCCTCCAGTCCCATTCCGTCCAGGCCCATTACCTCCTTTCCCCAGCAGCAGTGACTCCTTCGGAGCCCCTCCACAAGTTCCATCTAGGCCTACGAGGGCCCCGCCCAGTGTCCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197959-'61-76,'61-74,62-76=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.291 A=0.641 C2=1.000
Domain overlap (PFAM):
C1:
PF0221213=GED=PU(41.3=69.1)
A:
PF0221213=GED=PD(56.5=68.4)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCGCAACCTCGTAGACTCCT
R:
ATGGAACTTGTGGAGGGGCTC
Band lengths:
295-522
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains