HsaINT0007978 @ hg19
Intron Retention
Gene
ENSG00000091879 | ANGPT2
Description
angiopoietin 2 [Source:HGNC Symbol;Acc:485]
Coordinates
chr8:6378699-6385197:-
Coord C1 exon
chr8:6385076-6385197
Coord A exon
chr8:6378932-6385075
Coord C2 exon
chr8:6378699-6378931
Length
6144 bp
Sequences
Splice sites
5' ss Seq
CAGGTAATA
5' ss Score
8.55
3' ss Seq
ACAATTCTTTTCCTTACAAGTTT
3' ss Score
4.86
Exon sequences
Seq C1 exon
GTATTAAATCAGACCACGAGACTTGAACTTCAGCTCTTGGAACACTCCCTCTCGACAAACAAATTGGAAAAACAGATTTTGGACCAGACCAGTGAAATAAACAAATTGCAAGATAAGAACAG
Seq A exon
GTAATAACAGTACTAAAACATTTATAATTCAGGACTGCACACTTTCCAGATATGAAAGTCGGTCTCAAATGATGAATTATCAGAATGGTGAGTTTCTTCATGTCTAGTGTAAGGGTCAGAAACCTCATGAGGGAGGAGAAGGGAGAGGGCTTGGAGAAAATTCCTGCACAGGCACAGCTCTCCTAACACAGTCCTGGATTTTACCTTTCATTCCCTGGCCCCTTAAAGATCCTCTTAGAGTAATCCTCCAAACCCTGCCTCAGTATTCTGCATGCTAATCTATTATAAAAATACAGCTAGTGCTGTGGAGTGAAAGAACCACTGGCCCAAAAGATCCTCTTAGAGTAATCCTCCAAACCCTGCCTCAGTATTCTACATGCTAATCTATTATAAAAATACAGCTAGTGCTGTGGAGTGAAAGAACCACTGGCCCAGGCATTTTATTTCAGTATTAACTTGACCAAGATCCTTTGCCCTTGGGGACTTAGCTTCACTCAACGCAGAATGGTCTATAGTATGAAAGCTACACTTATACTGTAAGCCAATGCACATTTTATGATCCAATGTTTCCTCTTCAAACACACGATAAAGTAAAACCAAAAATATTAAACATGATTATATTAATATTTAAATAAAATATAGAAAAATCTCAAGATCAACAATAGAAAAAAAATTGTAGGGGATAGGTGGGGACTGTTTTCATATGTCTGTTCCACTTGGGACAAAAGAGGATAATTTTATGCACATACCTGGTGTGCCTATTTCCTTGTTTTTAATGAAGACATGTATATACAACATGGAACATGGCTATAACAATATATCCTATTTCACAATTTAAATAATTCTTTATTCTTAACCAAAAATGATAAACTTCTTGTTCAATAATTGTTCTTTACTGTTAATCAAGAACTAAGCTGAAATAATTCTTTCTGTCCTTTGGATACCAAGTTTAAGTCATTATTGATTTAGGGTTTTGAAAAGCAAATAGATTTTTAAAATTCAAATATTTTTCTTTCATGTTTCAGATTTCTCCTCTACAAACAGTAAATGAACATTTGAGACCAATCATTGAGATATAACAATCCTGCTAATTTCATTTTCTTTTCTGTGTTTTTTTTTTGAGACAGGGTCTCACTCTGGTTGCCCTGGCTGGAGTGCAGTGGTGCCATCTCAGCTTACTGCATCCTCAACCTCCTGGGCTCAGGTGATTCTCCCATGTCAGCCTCCTGAGTAGCTGGGACTACAGGCATGTGTCACACACCCAGCTGATTTTTTTTTTTTTTTTTTTTTTTTTTTTAGTAGAGGCAAGGTTTTGCCATATTGCCCAGGCTGGTCTCAAACTCCTGAATTTAAGCCTTCTGCCCACCGCAGCATCCTAAAGTGCTGGGATTACAGGCATGAGCCACCGTACCTGGCGTCGTTTTCTTAAAATAGTCTTACTTAGTAATGTTCTCTTCAAAATGCTGCAGTGATTCCTGGAACACATGGGAGCTGGAGATTACTTTTCTCTTGCCTGTTATACAATGATGTCCGTGACAAACCTAGGATATGTCCAGTTTGTAGAACATACCCTAATACTGAATACTGTTTCCCCACTTGGGTTTCAAATTTAGCATGCTACAATGCTAAAACTACCAATTTGGGTCAATTATGTTCCCCAAATATCATCTTTGCAAATATTTTTCCAATCATATTGGCTTTCAACTATGCCTGTAGGAAGAATAAGCTTTTTCTCATCAGCTGTAGAAATCGTATTTTTTTGTCACAGATATGAAAGGAAATAAAAAGGTTTTTTTCATCAACAGCTATAAATAATAAAAAAAGAAAATAGTGTTGATGATTTTACAGGTGTATGAGTTCTGCATGCTGTGTTTTCTACCTTAATTCTGACTGGCCTATGATTTTATTTGCAAGTATATCATTACAAAAATATGCAAATGGTGTTTCACATTGGACAAACCACATTTTAAATAATCTTTTATAATTCCCCAAAAGTGCAATTGCTTTCTTTATAGAATAGATTCAAGCCAGGCACAGTGGCTCATGCCTATAATCCCAGCACTTTGGGAGGCCAGAGTGATAGGATTTCTTGAGGCCAGGAGTTTGAGACTAGCCAGGGCAATATAATGAGAACTCATTTTTACAAAAAATACAAAAATTAGCCAGATGTGGTGGCACACACCTGTAATCCCTCCTATTTGGATGGCTGAGGCAGGTGGATCGCTTGAACCTAGGAGTTTGATACCAACCTGGGCAACAAAGACAGACCCCCATCTCTCCAAAATTACATACTAATTTACAACGATCAGGGGGCTGGAATACATTTAAGAGCTACAATTGAATATCTAATAATTATTATTAATACTGATTGTTATTGCTTATGGGCGAGATATGTAATGGGTAGCCAGTTCCTTGGCTGGTTAATATTGTTTGCAGGGTTAAAGAGTCAGAAAATGTTACTGTCAAAAAAAGGTGGATTTACCAGATCATTCGAACTAAAAGGGGCCCGAGAGGCCATGAAATCGAATGCCTTCATTTTACATAGAGCTTTATTTAGATAGATATTCACCTAGACAGACATGCACCTGAGGTCCACAGCAGGGTGTCTGCCCTTGTGACACAGGAAGCCATGTGCAGAGGTGGGATTCCCAGCCTAAGGCTACTTCCTTTCACCTGAAGGTGCTCGTGACACCAAAGGTGACTTCTCAGGGTCTCCATTTTCTCTTCAGTGAAACCATGATCTTCATATGTATTCCCTGTGATAACTTCTATTTACAGACCTTACATGGCCACAAGGGTAGTTTTTCCTCAAGGGAGACATTCATAGCCTTGTCTTTTTAGCTTGATGATGTGAAGACCATCAAAACATCTAAATTTCCGCAGGCTTAAGACTATGGTTCATGATGCTTTCATTTCTTGATTTTTCTCCAAAACCCTAAAAAACACCTCGTACATGGTAGGTGTTCAATACATCTCTGTTAAACGGAAGGTAAGACGTGATCTGAACCCAACTATCACTCAGTGAAACGTGTATGTCAATTTCACATGCTTTCGGTTCCTAGGAAAGTAAGTGCAAAGTGACTCAGGAGGCTTCAGATAACTCACAGCAGTGTTAAATGGCCGGTTCAAGGTTTCTTTATCAAGCAGGTGGGAAAATAATGTTTCTCTGCTCTTCATATGCCTTCGCAGAAAAGCTAGTGAAATGTATAGAATATTTCACCAGCTTCTAATGTGACATTAACAGAAGCTGTGGTAACTTGTTAGTAGACAGAAAATAATTCTGAAACATAAAGATGCCATCATTGACATATTTCATTATTAAATAAGACAGCTGACTTATACGGGACTCAAAAAAGGGAATATGAGGTCCCCTTCCTTTAAAACAAAACTCTGCAATGTGCAAATTCATGTGTACTAAACTTTATATTGGAAGGAAAATGTCAGAGAGAGGAATCTGACATCTGGTCACTGTTTTTCTATTTTTAAAAGTGTCTATATTTTGAAAGCTTTATTTACTGGCCTTGTACAAACAAAATGAAGATATTGAAACATCTTTAGTTGCTGCTTTTCCTGCAATTATCACAGAAAGCCTCTTTAGGTGCTGAATAATGTAGTGTCAGGCTATCCAATTTTCCTCTTGTATCTTATTAAAAAAAAAAAAAAATGCCAGCCAGGCACGGTGGCTCATGCCTGTAATTCCAGCACTTTGGAAGGCCGAGGTGGACGAATCAGGAAGTCAGGAGTTCGAGACCAGCCTGGACAACATAATGAAACCACGTCTCTACTAAAAATACAAAAAATTAGCTGGGCGTGGTGGCACACCTGTAATCCTAACTACTCAGGAGGCTGAGGCAGGAGAACTGCTTGAATCCGGGAGGCGGAGGTTGCAGCGAGCTGAGATCGCGCCACTGCACAACAGCCCAGGCCACAGCGCGAGACTCCGAGACTCCATCTCAAAACAAAAAACAAAAAACCCTGCCAAATACCTTGACTGTGCATGTCTTTGAGTTTGTTCCTGGGAAACAGTTAACATTCTCAAATACATAGTCTCTACTCTCTTGGATTTGTTTCCTCTGGCTTAATGGACAGGAACTATTTTTAGTTTAAAAGTGGTATGCTCTTCATTGAACATATTTATAGCAATGTATGTTTATAAGTTGAAATTAGGAAGGCAAACTATATAACCATTAATAAAGTATCTTAGGACTTACATGGCATAATTTTACCAGCTCTCTAAATAATTTTTAAAAAGCTTTTCTGCCAGGCGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCAGGGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCACCCTGGCTAACACGGTAAAAGCCCATCTCTACTAAAAATACAAAAAGTTAGCCTGACATGGTGACATGCGCCTGTAGTCCCAGCTACTCGGGAGACTGAGGCAGGAGAATAGCTTGAACCTGGGAGGTGAAGGTTGCAGTGAGCCAAGATGGCACCCTTGCACTCCAGTCTGGGTGACAGAGCGAGACTCCATCTCAAAAAAAGAAAAAAAAAAACTTTTCAAGGGCTTGGCTCACATATTAACTGTTATGTATTAAGTACATGCCATAGCGCTGGTTAGATTTTTTAGAGAAGGAATGGGGCCACATTAAAAGGAGAGAAGCAGATTTCAGAGTCAGAAAGTTCTGGGATTGTATTCTGCCCCTGCCACCTGCTGTGTGTGACTTTAGGTATGTGATTCATTCTTCCTACATTTCTTTTCTTTTCTTTTTTTTTTTTGAGACGATGTCTCGCTCTGTTGCCCAGGCTGGAGTGCAATGGCATAATCTCAGCTCACTGCAACCTCCACCTCCCGGGTTCAAGCAGTTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACATTCATGTACCCCCACGCTTGGCTAATTTTTGTATTTTTAGTAGAGAGAGGGTTTCACCATGTTGGCCAGCCTGCTCTCAAGCTCCTGGACTCTAGTGATACACCTGCCTCAGCCTTCCAAAGTGCTGGGATTATAGGTGTGAGCCACTGAGCCTGGCCCTCAATGTCCCTAAGTTTCAATTTCCTCATTGGAAATGGGAATAATAATGTCTATATTAACGTTAACAAACATTCATTGACTGTTAATGTATGACAGGCGCTAGTCTAAGCGTTTACATTTTTTTTTCTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCATGATCTCAGCTCACTGCAAGCTCCGCCTCCCGAGATCACGCCATTCTCCTGCCTCAGCCTCCAGAGTAGCTGTGACTACAGGCGCCCGCCACCACGCCTGGAGAATTTTTTGTATTTTTAGTGGAGACGGGGTTTCACCGTGTTAGCCAGGATACTCTCAATCTCCCGACCTCGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAAGCGTGAGCCACTGCGCCCGGCCAGCATTTACATTTTAAAACCCATTTGTTCCTCACACCAACCCCATGACCTAGGTGATAGTATCCTAATTAACAGGTGAGGACATTAACGCATAGGGTGACTAAGTAAACTGTTCCAAGTCGCAGGGCTGGTAAGCCAGTACTTGAGTCTGGGAGAAGTATTCACCTCCCCATGAAGGAGTATTTCTCACATAGCATTAAGTGCTATTATTATCATTAGGATTAATATTAAAATATAAATAGTTTAGGAGAAAGCTAATATCCTACCCAAGGGTCCAGCCCAGTTGAAACTCTCCCTTCTCAAAAAAGCACTTCATGAGCACTAAGCTTGAAAGAGCAGCACCTTTCTTCTGAGCGCTGCAGCATCTAATACAAAAAACACCCATATCCCACCTATCCTGGACCAGATGGGGTACCTTTTCTTGTGTGTATGCATAAGTCTGCATGTACATACATATATGCTTATACGTTTACATATATACACACATTTATATATCTAATCTTCTCAGCAAGTTTCAGAGATTCCTTAGGGCTCTGGTAACATCATATTACTTTATAACCACTACAATATCTTAACAGAGTACCTTGGAGAAGTAGAAATTCAATAAATATAAAATATTTCATTAGAATAGCCTTCACTAACTAACAATTCTTTTCCTTACAAG
Seq C2 exon
TTTCCTAGAAAAGAAGGTGCTAGCTATGGAAGACAAGCACATCATCCAACTACAGTCAATAAAAGAAGAGAAAGATCAGCTACAGGTGTTAGTATCCAAGCAAAATTCCATCATTGAAGAACTAGAAAAAAAAATAGTGACTGCCACGGTGAATAATTCAGTTCTTCAGAAGCAGCAACATGATCTCATGGAGACAGTTAATAACTTACTGACTATGATGTCCACATCAAACT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000091879-ANGPT2:NM_001147:3
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.070
Domain overlap (PFAM):
C1:
PF0149614=V_ATPase_I=FE(22.0=100),PF0497710=DivIC=PU(60.0=73.2)
A:
NA
C2:
PF0149614=V_ATPase_I=FE(42.9=100),PF0497710=DivIC=PD(38.0=24.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)