HsaINT0018505 @ hg19
Intron Retention
Gene
ENSG00000141867 | BRD4
Description
bromodomain containing 4 [Source:HGNC Symbol;Acc:13575]
Coordinates
chr19:15367775-15374359:-
Coord C1 exon
chr19:15374231-15374359
Coord A exon
chr19:15367985-15374230
Coord C2 exon
chr19:15367775-15367984
Length
6246 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
GCATGTCTTTCCCTCACCAGGAT
3' ss Score
9.39
Exon sequences
Seq C1 exon
TCTAAACTGGAGGCCCGTGAGTACCGTGATGCTCAGGAGTTTGGTGCTGACGTCCGATTGATGTTCTCCAACTGCTATAAGTACAACCCTCCTGACCATGAGGTGGTGGCCATGGCCCGCAAGCTCCAG
Seq A exon
GTGAGGCTTGGGAGGGCGCAGCCACCCTCAGCAGAGCAGGCTGAGGTCCTCGTGGGAGCAGACTTCTGTGGGCCTTGGCAGAGTTTTTTTTTCTGTCACTTTCCTTGGGATAATGCCATGTTGCTTTAGAAAAGTGCCTAAAGTCAGCCTAGTGCATACATTTTAAGTTGGGGTTATTCAATTAAAGCAGAGTGGGTGTTCCACTGCAAGCCCCCTCCACCAGCACTCATTTGCTTTTGGCTGGAAGACCGGGTGTGTGCTGTGCATGGCCCAGTCTCTTCTACAAAACACACCTGTCTCAAGTGGGTTGGGGGTGGGGGGCACTCTTGCCGAGAAGTCGCTGTCACAGTCGTGAGCTGAGGACATCTGCACTGTGGACATCCCTCCACCAGAGCCGTAAGAGCCTTCTAGCTGCAGAGTGGTTGTTTCCACATGGCCACAATTCTGATTGGGGGTCCTGGGTCACTTCCTTCAAGTTGAGAGCCTGGGTGGTGCACAGTGTGAAGTACACGTGTGGGCGGGGAGGGGAGGTTACAGCATAGATGTGTAAACTTAATTTTTTTAAAAAAGGAAAAATACCTAAGTTTAAAAAATGACTTTCTTTGAATAATAAGATTGGGTTAAAAATTTTGGAGAATAAAGTCAATATTTAGTACTATCATCATCATCTTTTCTATTTTTTTTGTTTTAATTATTGGAGACAGGGTCTCGTTCTGTCACCCAGGCTGGAGTGTAGTGGCACAGTCATAGCTCACGGCAGCCTCTGCCTTCCAGGTTCAAGCGATCCTCCCACCTCAGCCTCCCGAGTATCTAGGACTACAGGCTTGCACCACCATGCCCAGCTAATTTTGCCTCGTTTATTTTCTTTTTTTTTTTCTTTTTTTTTTTTTTTTTTAAAGAGATGGGTTTTGCCATGTTGCACAGGCTGGTCTGGAACCCCTGGGCTTAAGTGATCCACCTGCCTCGGACTCTCAGAGTGCTGGGATTAGAGACTCATCTTCTTTTTTAAATTCTTTAAGACTGTAGATAAATGATCATAAAAATTCCCAGCATCTTCTCCCCAAGGCCATGGGTTGCTTCTGTTCTCAGGGTCAGAGCCATCATGAGGTGCTGATGTGCTCATTGTAGGCCTCAGCGGGCTTCTGCACACCTGGCTGTCGCAGCCATCTGCTTCCAGGGCAGAAGTGAGGACTTGGAAAGCCTTTGGTGACCTGTGGATCGGTGCCAGGCAGAGCCCCACTGCCTGCCTGCCTCCCAGCTGCACTAGTTCTCATGTTGTCCTAGACTCCCCAGCATAGCAGCCCGTACCTGCTCCCACTGGACCTAAGGCACTGTCTCTCCTATTCTCTGTGGATCAGGGGCTGCCTTGGGTTCAGAGGACATGTGCTCAAACTCTTGAGGTAGGATAAACACTTCCCTTGTGAAGTTTGTTGGTCTCTTTCTTACTAGTGTGGATGTGGCTCTTGTTATTTAAATGCATGCTCAGGCTTGGAGCTTTTTATTTCTACTTTTTTTTATTTATTTATTTTTGGAAACGGGGTGTCATTCTGCTTACTGTAGCCTCAACCTGCTGTGCTCAATTGAGCCTCTCAGGTAGGACAGCAAGCGTGTGCCACCATGCCTGGCTAATTTTTGTATTTTGGTAGAGATGGCATGTCACTGTATTGCCCAGGCTGGTCTCAAACTCCTGGGCTTAGGTGATCCACCTGCTTCAGCCTCCCATACTACCAGGATTACAGGCATGAGCCACGGCACCTGGCCTGTTTCTTAGTTTTATTTTCTGTGACTTGGGGAATTGTTGCCCTCTCTTCACTTTGGTGTTGTCTGTGTGCCTTCTTCACAAACAACATTGCCCCTTCATCATTCATGTTTGCATTTCCCATCCTTGAAGGAGTTCAGGCTTTTTAATTTCTTTCTTTCTTTCTTTCTTTTTTTTTTGAGATGGAGTCTCTTTCTGTCGCCCAGGCTGGAGTGCAGTGGCACGACCTCAGCTCACTGCAACCTCCGCCTCCTGGTTCAAGCAGTTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCACGCCACCACGCCCAGCTAATTTTTGTTTTTTAGTAGAGAGGGGGTTTTGCCGATTGGTCAGGCTGGTCTTGAACTTCTGACCTCATGATCTGCCTGCCTGGGCCTCCCAAAGTGCTGGAATTACAGGCGTGAGCCACCGTGCCCGGCCAGACTTTTTAATTTCAATGCAGTTTTTGTTCAGGGCCACCCGGTGGCAGTGGCGCCCTCAGATTGGTGCCTTCAACTCCTCCACCGCTCCCTCTCTCCCACTCTCTTGAGAAGACAGGGGCGCAGCTTTTGCCCACACTGCTCACATTGATACCCATGCCCTTCATCTACTCTCATAGGAAGAACTCAGCAGAAACAAATTCTCTTCCAGCACCAAAGGTGACTGTTTTGAGCTACTTTACTAAGAGAAAGAAAAGAAAAAGCACCCTCTGATGTGTTCTAGCCCTTCCTTCCTCATTTTTGTCTCATTTTTTCTGTCCTCTCCTGACACCCTGGAGCCACCTCCTTTTCGCAGATTTTCTCCAACAAAGATTTTTGGGTTTTAAGTGGTTTTTTTTTTTTTTTTTGCATTTTTCTCCTTCTGAGAGGGGAGTAAGCCTGCCTGAATGTAGAGTTTACCAAGGCCACTGGATGTCTGTCACACCACAGACACTGCAGCAGTAGAGTTTCTTCCTACACACGGGCTCCAGGTGCCGGACTGGAGTGGACACAGGCCTCAATCTCAAGGGGGCCTAGTGCAGGCAAGGGGTGGGGGGTGCTGTAGGTGGGCTGCCTCTGGCCCAGCCTGTTTCGCCTGCCCTTGGGAGGGACACCTCTCTGCCAGTGCTTGGTAGAGGTGTTTCTGTTTGAGCAACAGAGTTGATGGTGGAGGGTTCCAGAGCAGGCTTCTCTTCAGTGGGCAGTTGTGTTTGTGGCATTTCAGGCTTTGTTTTTCTTACTTCTCTCTACTTTCTCTGCATCAGCAGGTAGAGAGCAAATTCTCCATCAGGGAAGGGGAGGGACAAAGCTTCCAGCCCTTGCTCACTTCTTCAGGAGCTATTGGGACCTGCTTAATTGGGTCTCTTAATTTGGCTGGGCCCAAGAAGTGGGATTATCTGGAAAGTTACTTGGAAAAGGAGCCACTTTATTTTTCTCTCTGAGCCTCTAAATTCTCGGGTCATTGAGAAAACCTGTGTTCCACAGCCTGACAGCTGAGATACTTGTCTGAAACCAGTGAGGTGTGCTGAAACTGAGAAGCATGACCTCAGACCCAGACCTCCAGAGGAGTGAGGTGTAGGTCTGTGGGATGCCGGGCAGGGGGCTGGGCCTCAGCTGGGTCTCAAGAGACTGTCAGCCCAACAGAATGCCTGCACTCGGTGTTCCCTGGCGGGTGCTGGTGCCTGCTACCCCTCACCATCACCATCCTCCCTTGTGAGAGGCTTGCCTCGGTGCATCTTGAATTGGGCTTTACTGTCCTCTTGCTGGCCCCATAGCACCCCTGACTGTGTTCTTTTCACTCTTAGGTCTCAGCACACTTCCAGTTCATGGCAACCCCTTGCTGCCCATGTGTTCATTCACCTTTCTGTTTCCAGCTAGACTGAGCTCCTTGAACAGGGAGCTCGTCATTCCTGTCTACCATCAAGCTGGTACTTGGAGACTTGTGACTGTTGAAGCCACACAGCAAGGTTTTCCTACAGCAGCCCTGGGCCCACTGGCTTGTGGGTTTCCCAGGATGCCCCCCACTCAGGCTACAACAAGAGTTCTCACATCCAAGAGACAGGGAAGGATGACAGGGTCACACAACTGGACACGCCAGGAAGCTGGCAGTTCCCAGTCCCACCAATGTTAGTTTCTCATCTTAGCTGACTTTGTGTCTTGTATTTTTTGCTCTTTGTTGTTGGGGCCTTTGGAGAGCCAGGGCCATGAGCACCCAGGGAATGGAAGGAGGCCTCAGAGTGAATGCCACACACCCCCACCCCAGCATTTACCCAACAGTCATCACCTGGTGGGGAGGAACAAGGACATCCTCAAGTCTTGAAGCTGGCCCAGGCTTACAGACCAGTTCGCTGAGGTAGCTACCACTCAGTAGAGGGCACTCCCTTTGTCCTGGGAGGCATAGCTGATTATCTCCCTTCATGATGTCCTGGCACTTCTGAGGCCCACTTCTCTAACCTGCTTCCTGCTGCTTGGCAGCAGGCCTGGCTCTTCCAGAAGCTCATGTGGCCCCAGCTGCCTCTTGGAGTCATTTTGGGACCTGAGCCCACCCACATCCAGGGCACTACCCACCTGCCACGTAGCCGGGTGCTGCAGGGCTAGGGATCTGTCTTACTCTCTCACTGGGGCCTCCACTCTGATGTGAAGCCCCCCACCTTTTCCTCCCTGGGCCCCACTCCTGGGAGGCTAACTGGTGATGGCCTCTGGTCGTCCCTTGTTGTGTATCTTCTTCCTTGTCTCAGACCTGCTCAAGGAGTTATTTCTGAATAAAGGTATTTGCTGGGTGCAGTGGCTCATGCCTGTAATCCTGGCACTTTTCATTGTAGACCACCTTGTGGGAGGATCCCTTGATCCCAGGAGTTGGAGACCAGCCTGGGCAACATGTCAAAACCCTGTCTGCACAAAAATTTAGCTGGGCATGGTGGTCTCAGTTCTCAAGGAGGCTGAGGCAGGAGGATCTCTTGAGCCTAGGAGGATGAGGCTGTAGTGAGCCATGATTGAGCCATTGATTGCATTCCACCCTGGGCAACAGAGCAAGGCCCTATCTCCAAAAAGAAGAAGAAGAAGAAAGAAAGAAAAAAGTTATTGGGCCAGGCGCAGTGGCTCACGCTGGTCATCCCAACCCTTTGGGAGGCTGTGGCAAGTGGATCTGTTGAGGTCAGGAGTTTAAGACCAGCCTGGCCAACATGGTAGAACGCTGCCTCTGCTAAAAATACAAAAATTAGTTGGGCATGGTGGTGTGCACCTGTAATTCCAGCTACTTGGGAGACAGAGGTTACAGTGAGCTGAGATTGCGCCACTGCACTCCAGCCTGGGTGAAGACTGTCTCCAAAAAAAAAGTTATTGGCTAAAAGAAGTCATACTCCGGGTGTCCTGGAGGGGAGGGAATCAACACCACAGTTATATGGGATGCCTGCTCCAGCAGCGTGGGAGAGGAAGCCTCAAGGAGTGTTTCCTGAGCCATCAGGAGGGGATTCCAGGGCCGTGGTCCTCTCTGAAGCACTGACACACATTTGGGGGAAGGTCTTTGCCATGGTGTGTTTCCACGATGATCAGTTTATTCCTGGTTTGAAGCGGGTCCCAGAATCCTGCTGGGAAGCCAGGCCTGTGCTTCTGCCTCTGTCTTGAGCCATCACTGGATTGAGCACAGCGCCCCCGGGGTAGGGCAGGGACTTGACAGCTGGCTGGCAGTATGTGTGGCCAGACCCCAGTGTCCATGCATGGCTGCTGTTCCCTGAGCTCCATGACCCCACGTGGTTCCATCTGATTGCTGGATCTTAGGGTTGAAAGGTCTTAGGGTCTCCTGCGCACAGTGGCTCCCTCCTGTAGCCTGTCCTCAGTGCCCCACACCTGCTGCCTAAACCTCTCTTACCTTGTCCTGTGTGTGCTGGAGATGCCTCCTCCAGTGGTGCAGCCCTGCTTGGTTAAGTGCTGCAGGGGCTATCTGAGGAATGAGGAGACCGACTTAGAACCGTGTCTGCTACAGCAGAGCCTAGTCCCCTAGAGGAGGTGCGCTTGTGGCAGGTACATTCCCACCGGGGACCTCTGCGTGTGCTGTGTCCTCTGCCTGGAATGCCCTCTCAAACCACAGACAACTCCTGCTCCCCCGCACGCATCTGGTGGGAGCCTCGGCTAACTGTTTTGGGGTTTGAGGATGCCCTTGGTCCAGTACCATCTCAGACTTCAGTGAGCTGGCTGTCTTAGTGGCCTGGGTCTCATGTCCTTGCCTGGGCGGTGTCCTCCAGGGAGTGAGTGCCCCGCTATCTCTGGACCACCTTGTTCTTCAAAGTGAGATTTGAGAGAAGAGTGTTGCAAGAGTTGTCAGAGGCCCTTGGCTGGCCCTTGCCCCTGTCTCGGCAGCAAAGAGACAGGATCACCATCCTCTTTCGCCCTCGGTTGCTTTCTGTTGAGTTGGCCCCAGCAGCCAATGAGGGCAGGTGATGCTAGGCCGCGGCCTGGGTACCCAGCAGCCGTCACAGCATGTCTTTCCCTCACCAG
Seq C2 exon
GATGTGTTCGAAATGCGCTTTGCCAAGATGCCGGACGAGCCTGAGGAGCCAGTGGTGGCCGTGTCCTCCCCGGCAGTGCCCCCTCCCACCAAGGTTGTGGCCCCGCCCTCATCCAGCGACAGCAGCAGCGATAGCTCCTCGGACAGTGACAGTTCGACTGATGACTCTGAGGAGGAGCGAGCCCAGCGGCTGGCTGAGCTCCAGGAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000141867-BRD4:NM_014299:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.140 A=NA C2=0.900
Domain overlap (PFAM):
C1:
PF0043920=Bromodomain=PD(44.9=93.0),PF057648=YL1=PU(23.0=86.0),PF056676=DUF812=FE(21.9=100)
A:
NA
C2:
PF057648=YL1=FE(42.9=100),PF056676=DUF812=FE(35.9=100),PF139251=Katanin_con80=PU(54.5=42.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)