HsaINT0018505 @ hg38
Intron Retention
Gene
ENSG00000141867 | BRD4
Description
bromodomain containing 4 [Source:HGNC Symbol;Acc:HGNC:13575]
Coordinates
chr19:15256964-15263548:-
Coord C1 exon
chr19:15263420-15263548
Coord A exon
chr19:15257174-15263419
Coord C2 exon
chr19:15256964-15257173
Length
6246 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
GCATGTCTTTCCCTCACCAGGAT
3' ss Score
9.39
Exon sequences
Seq C1 exon
TCTAAACTGGAGGCCCGTGAGTACCGTGATGCTCAGGAGTTTGGTGCTGACGTCCGATTGATGTTCTCCAACTGCTATAAGTACAACCCTCCTGACCATGAGGTGGTGGCCATGGCCCGCAAGCTCCAG
Seq A exon
GTGAGGCTTGGGAGGGCGCAGCCACCCTCAGCAGAGCAGGCTGAGGTCCTCGTGGGAGCAGACTTCTGTGGGCCTTGGCAGAGTTTTTTTTTCTGTCACTTTCCTTGGGATAATGCCATGTTGCTTTAGAAAAGTGCCTAAAGTCAGCCTAGTGCATACATTTTAAGTTGGGGTTATTCAATTAAAGCAGAGTGGGTGTTCCACTGCAAGCCCCCTCCACCAGCACTCATTTGCTTTTGGCTGGAAGACCGGGTGTGTGCTGTGCATGGCCCAGTCTCTTCTACAAAACACACCTGTCTCAAGTGGGTTGGGGGTGGGGGGCACTCTTGCCGAGAAGTCGCTGTCACAGTCGTGAGCTGAGGACATCTGCACTGTGGACATCCCTCCACCAGAGCCGTAAGAGCCTTCTAGCTGCAGAGTGGTTGTTTCCACATGGCCACAATTCTGATTGGGGGTCCTGGGTCACTTCCTTCAAGTTGAGAGCCTGGGTGGTGCACAGTGTGAAGTACACGTGTGGGCGGGGAGGGGAGGTTACAGCATAGATGTGTAAACTTAATTTTTTTAAAAAAGGAAAAATACCTAAGTTTAAAAAATGACTTTCTTTGAATAATAAGATTGGGTTAAAAATTTTGGAGAATAAAGTCAATATTTAGTACTATCATCATCATCTTTTCTATTTTTTTTGTTTTAATTATTGGAGACAGGGTCTCGTTCTGTCACCCAGGCTGGAGTGTAGTGGCACAGTCATAGCTCACGGCAGCCTCTGCCTTCCAGGTTCAAGCGATCCTCCCACCTCAGCCTCCCGAGTATCTAGGACTACAGGCTTGCACCACCATGCCCAGCTAATTTTGCCTCGTTTATTTTCTTTTTTTTTTTCTTTTTTTTTTTTTTTTTTAAAGAGATGGGTTTTGCCATGTTGCACAGGCTGGTCTGGAACCCCTGGGCTTAAGTGATCCACCTGCCTCGGACTCTCAGAGTGCTGGGATTAGAGACTCATCTTCTTTTTTAAATTCTTTAAGACTGTAGATAAATGATCATAAAAATTCCCAGCATCTTCTCCCCAAGGCCATGGGTTGCTTCTGTTCTCAGGGTCAGAGCCATCATGAGGTGCTGATGTGCTCATTGTAGGCCTCAGCGGGCTTCTGCACACCTGGCTGTCGCAGCCATCTGCTTCCAGGGCAGAAGTGAGGACTTGGAAAGCCTTTGGTGACCTGTGGATCGGTGCCAGGCAGAGCCCCACTGCCTGCCTGCCTCCCAGCTGCACTAGTTCTCATGTTGTCCTAGACTCCCCAGCATAGCAGCCCGTACCTGCTCCCACTGGACCTAAGGCACTGTCTCTCCTATTCTCTGTGGATCAGGGGCTGCCTTGGGTTCAGAGGACATGTGCTCAAACTCTTGAGGTAGGATAAACACTTCCCTTGTGAAGTTTGTTGGTCTCTTTCTTACTAGTGTGGATGTGGCTCTTGTTATTTAAATGCATGCTCAGGCTTGGAGCTTTTTATTTCTACTTTTTTTTATTTATTTATTTTTGGAAACGGGGTGTCATTCTGCTTACTGTAGCCTCAACCTGCTGTGCTCAATTGAGCCTCTCAGGTAGGACAGCAAGCGTGTGCCACCATGCCTGGCTAATTTTTGTATTTTGGTAGAGATGGCATGTCACTGTATTGCCCAGGCTGGTCTCAAACTCCTGGGCTTAGGTGATCCACCTGCTTCAGCCTCCCATACTACCAGGATTACAGGCATGAGCCACGGCACCTGGCCTGTTTCTTAGTTTTATTTTCTGTGACTTGGGGAATTGTTGCCCTCTCTTCACTTTGGTGTTGTCTGTGTGCCTTCTTCACAAACAACATTGCCCCTTCATCATTCATGTTTGCATTTCCCATCCTTGAAGGAGTTCAGGCTTTTTAATTTCTTTCTTTCTTTCTTTCTTTTTTTTTTGAGATGGAGTCTCTTTCTGTCGCCCAGGCTGGAGTGCAGTGGCACGACCTCAGCTCACTGCAACCTCCGCCTCCTGGTTCAAGCAGTTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCACGCCACCACGCCCAGCTAATTTTTGTTTTTTAGTAGAGAGGGGGTTTTGCCGATTGGTCAGGCTGGTCTTGAACTTCTGACCTCATGATCTGCCTGCCTGGGCCTCCCAAAGTGCTGGAATTACAGGCGTGAGCCACCGTGCCCGGCCAGACTTTTTAATTTCAATGCAGTTTTTGTTCAGGGCCACCCGGTGGCAGTGGCGCCCTCAGATTGGTGCCTTCAACTCCTCCACCGCTCCCTCTCTCCCACTCTCTTGAGAAGACAGGGGCGCAGCTTTTGCCCACACTGCTCACATTGATACCCATGCCCTTCATCTACTCTCATAGGAAGAACTCAGCAGAAACAAATTCTCTTCCAGCACCAAAGGTGACTGTTTTGAGCTACTTTACTAAGAGAAAGAAAAGAAAAAGCACCCTCTGATGTGTTCTAGCCCTTCCTTCCTCATTTTTGTCTCATTTTTTCTGTCCTCTCCTGACACCCTGGAGCCACCTCCTTTTCGCAGATTTTCTCCAACAAAGATTTTTGGGTTTTAAGTGGTTTTTTTTTTTTTTTTTGCATTTTTCTCCTTCTGAGAGGGGAGTAAGCCTGCCTGAATGTAGAGTTTACCAAGGCCACTGGATGTCTGTCACACCACAGACACTGCAGCAGTAGAGTTTCTTCCTACACACGGGCTCCAGGTGCCGGACTGGAGTGGACACAGGCCTCAATCTCAAGGGGGCCTAGTGCAGGCAAGGGGTGGGGGGTGCTGTAGGTGGGCTGCCTCTGGCCCAGCCTGTTTCGCCTGCCCTTGGGAGGGACACCTCTCTGCCAGTGCTTGGTAGAGGTGTTTCTGTTTGAGCAACAGAGTTGATGGTGGAGGGTTCCAGAGCAGGCTTCTCTTCAGTGGGCAGTTGTGTTTGTGGCATTTCAGGCTTTGTTTTTCTTACTTCTCTCTACTTTCTCTGCATCAGCAGGTAGAGAGCAAATTCTCCATCAGGGAAGGGGAGGGACAAAGCTTCCAGCCCTTGCTCACTTCTTCAGGAGCTATTGGGACCTGCTTAATTGGGTCTCTTAATTTGGCTGGGCCCAAGAAGTGGGATTATCTGGAAAGTTACTTGGAAAAGGAGCCACTTTATTTTTCTCTCTGAGCCTCTAAATTCTCGGGTCATTGAGAAAACCTGTGTTCCACAGCCTGACAGCTGAGATACTTGTCTGAAACCAGTGAGGTGTGCTGAAACTGAGAAGCATGACCTCAGACCCAGACCTCCAGAGGAGTGAGGTGTAGGTCTGTGGGATGCCGGGCAGGGGGCTGGGCCTCAGCTGGGTCTCAAGAGACTGTCAGCCCAACAGAATGCCTGCACTCGGTGTTCCCTGGCGGGTGCTGGTGCCTGCTACCCCTCACCATCACCATCCTCCCTTGTGAGAGGCTTGCCTCGGTGCATCTTGAATTGGGCTTTACTGTCCTCTTGCTGGCCCCATAGCACCCCTGACTGTGTTCTTTTCACTCTTAGGTCTCAGCACACTTCCAGTTCATGGCAACCCCTTGCTGCCCATGTGTTCATTCACCTTTCTGTTTCCAGCTAGACTGAGCTCCTTGAACAGGGAGCTCGTCATTCCTGTCTACCATCAAGCTGGTACTTGGAGACTTGTGACTGTTGAAGCCACACAGCAAGGTTTTCCTACAGCAGCCCTGGGCCCACTGGCTTGTGGGTTTCCCAGGATGCCCCCCACTCAGGCTACAACAAGAGTTCTCACATCCAAGAGACAGGGAAGGATGACAGGGTCACACAACTGGACACGCCAGGAAGCTGGCAGTTCCCAGTCCCACCAATGTTAGTTTCTCATCTTAGCTGACTTTGTGTCTTGTATTTTTTGCTCTTTGTTGTTGGGGCCTTTGGAGAGCCAGGGCCATGAGCACCCAGGGAATGGAAGGAGGCCTCAGAGTGAATGCCACACACCCCCACCCCAGCATTTACCCAACAGTCATCACCTGGTGGGGAGGAACAAGGACATCCTCAAGTCTTGAAGCTGGCCCAGGCTTACAGACCAGTTCGCTGAGGTAGCTACCACTCAGTAGAGGGCACTCCCTTTGTCCTGGGAGGCATAGCTGATTATCTCCCTTCATGATGTCCTGGCACTTCTGAGGCCCACTTCTCTAACCTGCTTCCTGCTGCTTGGCAGCAGGCCTGGCTCTTCCAGAAGCTCATGTGGCCCCAGCTGCCTCTTGGAGTCATTTTGGGACCTGAGCCCACCCACATCCAGGGCACTACCCACCTGCCACGTAGCCGGGTGCTGCAGGGCTAGGGATCTGTCTTACTCTCTCACTGGGGCCTCCACTCTGATGTGAAGCCCCCCACCTTTTCCTCCCTGGGCCCCACTCCTGGGAGGCTAACTGGTGATGGCCTCTGGTCGTCCCTTGTTGTGTATCTTCTTCCTTGTCTCAGACCTGCTCAAGGAGTTATTTCTGAATAAAGGTATTTGCTGGGTGCAGTGGCTCATGCCTGTAATCCTGGCACTTTTCATTGTAGACCACCTTGTGGGAGGATCCCTTGATCCCAGGAGTTGGAGACCAGCCTGGGCAACATGTCAAAACCCTGTCTGCACAAAAATTTAGCTGGGCATGGTGGTCTCAGTTCTCAAGGAGGCTGAGGCAGGAGGATCTCTTGAGCCTAGGAGGATGAGGCTGTAGTGAGCCATGATTGAGCCATTGATTGCATTCCACCCTGGGCAACAGAGCAAGGCCCTATCTCCAAAAAGAAGAAGAAGAAGAAAGAAAGAAAAAAGTTATTGGGCCAGGCGCAGTGGCTCACGCTGGTCATCCCAACCCTTTGGGAGGCTGTGGCAAGTGGATCTGTTGAGGTCAGGAGTTTAAGACCAGCCTGGCCAACATGGTAGAACGCTGCCTCTGCTAAAAATACAAAAATTAGTTGGGCATGGTGGTGTGCACCTGTAATTCCAGCTACTTGGGAGACAGAGGTTACAGTGAGCTGAGATTGCGCCACTGCACTCCAGCCTGGGTGAAGACTGTCTCCAAAAAAAAAGTTATTGGCTAAAAGAAGTCATACTCCGGGTGTCCTGGAGGGGAGGGAATCAACACCACAGTTATATGGGATGCCTGCTCCAGCAGCGTGGGAGAGGAAGCCTCAAGGAGTGTTTCCTGAGCCATCAGGAGGGGATTCCAGGGCCGTGGTCCTCTCTGAAGCACTGACACACATTTGGGGGAAGGTCTTTGCCATGGTGTGTTTCCACGATGATCAGTTTATTCCTGGTTTGAAGCGGGTCCCAGAATCCTGCTGGGAAGCCAGGCCTGTGCTTCTGCCTCTGTCTTGAGCCATCACTGGATTGAGCACAGCGCCCCCGGGGTAGGGCAGGGACTTGACAGCTGGCTGGCAGTATGTGTGGCCAGACCCCAGTGTCCATGCATGGCTGCTGTTCCCTGAGCTCCATGACCCCACGTGGTTCCATCTGATTGCTGGATCTTAGGGTTGAAAGGTCTTAGGGTCTCCTGCGCACAGTGGCTCCCTCCTGTAGCCTGTCCTCAGTGCCCCACACCTGCTGCCTAAACCTCTCTTACCTTGTCCTGTGTGTGCTGGAGATGCCTCCTCCAGTGGTGCAGCCCTGCTTGGTTAAGTGCTGCAGGGGCTATCTGAGGAATGAGGAGACCGACTTAGAACCGTGTCTGCTACAGCAGAGCCTAGTCCCCTAGAGGAGGTGCGCTTGTGGCAGGTACATTCCCACCGGGGACCTCTGCGTGTGCTGTGTCCTCTGCCTGGAATGCCCTCTCAAACCACAGACAACTCCTGCTCCCCCGCACGCATCTGGTGGGAGCCTCGGCTAACTGTTTTGGGGTTTGAGGATGCCCTTGGTCCAGTACCATCTCAGACTTCAGTGAGCTGGCTGTCTTAGTGGCCTGGGTCTCATGTCCTTGCCTGGGCGGTGTCCTCCAGGGAGTGAGTGCCCCGCTATCTCTGGACCACCTTGTTCTTCAAAGTGAGATTTGAGAGAAGAGTGTTGCAAGAGTTGTCAGAGGCCCTTGGCTGGCCCTTGCCCCTGTCTCGGCAGCAAAGAGACAGGATCACCATCCTCTTTCGCCCTCGGTTGCTTTCTGTTGAGTTGGCCCCAGCAGCCAATGAGGGCAGGTGATGCTAGGCCGCGGCCTGGGTACCCAGCAGCCGTCACAGCATGTCTTTCCCTCACCAG
Seq C2 exon
GATGTGTTCGAAATGCGCTTTGCCAAGATGCCGGACGAGCCTGAGGAGCCAGTGGTGGCCGTGTCCTCCCCGGCAGTGCCCCCTCCCACCAAGGTTGTGGCCCCGCCCTCATCCAGCGACAGCAGCAGCGATAGCTCCTCGGACAGTGACAGTTCGACTGATGACTCTGAGGAGGAGCGAGCCCAGCGGCTGGCTGAGCTCCAGGAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000141867:ENST00000263377:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.136 A=NA C2=0.888
Domain overlap (PFAM):
C1:
PF0043920=Bromodomain=PD(44.9=93.0),PF056676=DUF812=FE(21.9=100),PF057648=YL1=PU(23.0=86.0)
A:
NA
C2:
PF056676=DUF812=FE(35.9=100),PF057648=YL1=FE(42.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development