HsaINT0023205 @ hg19
Intron Retention
Gene
ENSG00000183597 | C22orf25
Description
chromosome 22 open reading frame 25 [Source:HGNC Symbol;Acc:25439]
Coordinates
chr22:20049053-20050965:+
Coord C1 exon
chr22:20049053-20049206
Coord A exon
chr22:20049207-20050860
Coord C2 exon
chr22:20050861-20050965
Length
1654 bp
Sequences
Splice sites
5' ss Seq
GGCGTGAGT
5' ss Score
7
3' ss Seq
CACTTCTCTCCATCCTGCAGGCA
3' ss Score
9.95
Exon sequences
Seq C1 exon
GCACCTACGGGCTGAGCAACGCGCTGCTGGAGACTCCCTGGAGGAAGCTGTGCTTTGGGAAGCAGCTCTTCCTGGAGGCTGTGGAACGGAGCCAGGCGCTGCCCAAGGATGTGCTCATCGCCAGCCTCCTGGATGTGCTCAACAATGAAGAGGC
Seq A exon
GTGAGTGGGCGGGTCCTGCTGGGGTGAGCCCCAGTGTCCCGCCACCAGGGCAGAGGGAAAGGCAGGCCCTGCTGCCCCGGGAGGCCCATGGAAGTGGCCAGGCTGGGTCCCCAGCTGCAGGGAAGCTGATGGATATCCTGTCCTCCCTGCCTGTCCCCTTGAGCCAGCTGAGGTTTCCAACACCAGGGACTTTTGATGACAGAAGATGGGCCCAGGCCCAGGCCCAGGCCCAGGGGAGGCTCAGTGCACCCAGAGGCTTGATGCAGCCACGTGGGGCCCAGAGCAGATGGATGCTCCCCTCTGCATGCCGAGAGCTTGTGGGAAGTTCCAGAAGATTCTAGACACTCAGCAAACCCAGGCGGAAGAGACACATCATGGAAATGAGTGGCTAGGGTCAGCACGCTCAGGGTTGATGGGCTTCCCGCAAGCGGTCTGTCCCCAGCGACCCTGGGCTGAGTGCTGGGCAGGGACTTGCAGTTCCGGGAACTGCCTGGGTGTAGGAGCTCCCACCCACTTCCTTGCCCGTAGGCCTCAAGGCCCCTCAGGGGCCAGGCACTGGGGTCTTCGTTGCCCCAGCCGGGGGTCCTGGTGCTTGCCATGCCAGCCTTTCTCCCACTGGGCGAGATGCCCCACCCATCCCTCGCTCCCCACCCAGGTCAGACCACTGCCCTGCCCAGGTGATCCAGCGTCCACTCCCACCCTGTCCAGCTTGCCCCCTTCAGAGAAGCACCCATGGACCATCTCCCACTCCTCCCCCTGGGGCCCCTTTCTGCCCCCTGCCTACCCTCCTTCTCCTCTGGGCCTCTGATAGGCGGCCTCGTCCTTCAGCCTCAGCATCGCTGCCTCACTGGAAGAGCCCCACCTGGGCATGCCCAGCAGCCCCTCCCAGCTGTAAGTCCACACAGCCCCCATCAATGTGCCATCTGGGGCAGGCCGAGGACCGGCCCTGGCTGCCCTCACTGATGGCTGGAGCCCCGATGCTAGCTACAATGGCTGGCTTGAGTGGACTTCTGTCACAGAGGCAAATGCCCACAGGGCACCTCTTGGGGCAGGCAGGGAGCTTGTATGTGCCATCTGGGGCCAAAGCTCCACGATTGAGTCATAAGTTAAGGGTAGATGGAGATTTTCCGCCTTGAGCAGAAACGTGGAGGAAACACGCCTGGTGTGTGACTCACGCCTGTAATCCCAGCACTTTGGGAAGCCGAGGTGGGCGGATCACCTGAGGTCAGGAGGTCAAAACCAACTTGGTCAACATGGTGAAACTCTGTCTCTACTAAAAACACAAAATTAGATGGCTGGGTGGTGCACGCCTGTAATCCCAGCTGACGGCTGGAGCCCCGATGCTAGCTACAATGGCTGGCTTGAGTGGACTTCTGTCAGGAGAATTGCTTGAACTCGGGAGGTGGAAGTTGCAGTGAGCCAAGATCGTACCATTGCGCTCTAGTCTGGGCGACAAGAGTGAAACTCCTCCTCAAAAAAAGAAAATAAGAGAAAAGAGAAGAGAAGAGGAAAAAGAAAAGAAGAAAAGAAACAACCCTTGCAGTTCCCCGGCCACTCCCCAGAGCCAGTTAGGCCACCAGGTGGGCTGGGGCTAGACCCGGCTGCGGGCGGGCCACAGAGGGACTAATGGCCACCACTTCTCTCCATCCTGCAG
Seq C2 exon
GCAGCTGCCAGACCCGGCCATCGAGGACCAGGGTGGGGAGTACGTGCAGCCCATGCTGAGCAAGTACGCGGCTGTGTGCGTGCGCTGCCCTGGCTACGGCACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000183597-C22orf25:NM_152906:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.153
Domain overlap (PFAM):
C1:
PF057427=NRDE=PD(1.1=1.9),PF057427=NRDE=FE(40.5=100)
A:
NA
C2:
PF057427=NRDE=PD(10.6=92.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACCTACGGGCTGAGCAAC
R:
CTGGTGCCGTAGCCAGGG
Band lengths:
258-1912
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)