HsaINT0027479 @ hg19
Intron Retention
Gene
ENSG00000092529 | CAPN3
Description
calpain 3, (p94) [Source:HGNC Symbol;Acc:1480]
Coordinates
chr15:42688998-42691850:+
Coord C1 exon
chr15:42688998-42689075
Coord A exon
chr15:42689076-42691689
Coord C2 exon
chr15:42691690-42691850
Length
2614 bp
Sequences
Splice sites
5' ss Seq
CTGGTGAGT
5' ss Score
10.1
3' ss Seq
CTCTTCTTCCAACCTCTCAGGAT
3' ss Score
8.62
Exon sequences
Seq C1 exon
ATGGAAGGACTGGAGCTTTGTGGACAAAGATGAGAAGGCCCGTCTGCAGCACCAGGTCACTGAGGATGGAGAGTTCTG
Seq A exon
GTGAGTCCAGAACCCAGGAAGACCCAGAAGGGTAAGGGTGGGGAAGAGAGGGGAAATCTCAGACCTCAGTCCCCAGCTAAGGTTATCAGATTCCAGCCCTTGGGAGATCTGGGCTGTGTTCTCCTCCAGCCCAAGGCCCAGCAAGGATGAGGTTCTGAGAGGAGCCTTCCAGGCCACAGGGACAACTGAGCCCAGGACCAGGCCAACATGACATGGCTCTTGCCTCCTGTGTGCCCCTCCGCCACACACTCTATTCCAGCCACAGGCACCCTGGCCTTAGCACAATTCTTTTCTGAGCCTAGGAAGCTCCACTTACCCTGATCTTCCAACGTCAACCTCACCCTCTCTCAGGTTGTTTCTATTCAGGCTTCAAGTCTCAGCTTAAGGAGAATTTTCAAGTCTCAGCTTAAGGAGAGCCCCCTAAGTTCCCCGAGGACTGGGATTAATTTATGATGCTCATCACCCTTAAAATTGTTTGCTTAAGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGAACGGATCACGAGGTCAGGAGATCGAGAACATCTTGGCTAACACGGTGAAACCCTGTCTGTACTAAAAATACACAAAAAAAGTAGCCGGGCGTGGCAGCGTGCGCCTGTAGTCCTAGCTGCTGGGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCAGAGGTTACAGTGAGCCCAGATTGCGCCACTGCACTCCAGCCTGGGCGACAAGAGAGACTCTGTCTTGGAAAAAAAAAAAAAAATGTTGTCTTAGTATAATGTCAAGGGAAAGGTTTTTTGTGTTTTTATTACTTTATTTTTTATTTAAAAACTATAATAGAGACGGGCCTCGCTATATTTCTCGGGCTGGTCTCAAACTCCTGGGCTCAAGCGGTCCTCCCACCTTGGCCTCCCAAAATGCTGGCATGTGGGCCTGGTCAACATATGGGACCCCAACTCTACAAAAAATTTTAAAATTAGCCAGATGTGGTGGCGTGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGAAGCAGGGGGTCACTTGAGCCCAGGAGGTTGAGGCTGCAGTGAACTATGATTGTACCACTGCAGTCCATCCTGGGCAACAGAGCAAGACACTGTCTTAAAAAAAAAGTGCTGGGATTACAGATGTAAGCCACCACACCTGGCCTTCTATTTTTTATGGATATATCATAGCTATATATATTTTTGGGGTACATATGTACCCATATTTTGGGGGTACATATGTACCCATATTTTGGGGGTACATATGATATTTTGATACACATATACAATGTGTAATGATCAAATTAGGGTAATTGAGATACCATCATCTCAAATATGTATCTTTTCTTTGTGTTGGGAACATTACAATTCTTTTCCTCTAGTTATTTTGAAAGATATATAGGCTGGGCGTGGTGGCTTATGCCTGTAATCCCAGCACCTTGGGAGGCTGAGGCGGGCAGATCACTTGAGGTCAGAAGTTCAAGACTAGCCTGGTCAACATGGTGAAACCCCATCTCTACAAAAATACAAAAATTAGCCAGGTGTGGTGGTGTGCACCTGTAATCCCAGCTGCTCAGCTGGCTGAGGCAGGAGAATCCCTTGACCTCAGGAGGTGGAGGTTGCAGTGAGCCAAGATCATGCCACTGCACTCTAGCCTGGGCAACAGAGCGAGACTCTGTCTCAAAAAATACACACACACACACACACACACACACACACACACACACACACACATATATATACACACATATATATACACACACATATACACACACACACGTCTGTATATATATGTGTGTGTGTATATATACACACACACACTATACTATAAATTCTTGTTTAGCTATGTTTGTCTTACTGTGCTATTGAGCATTAGAGCTTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCACTTTGTCGCCCAGGCTGGCATACAATGGCGCAATATCGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAACTAGGATTACAAGTGCCCGCCATAATGCTCAGCTAATTTTTGTATTTTCAGTAGAGATGGGGTTTCACCATGTTGGCCAAGCTGGTCTCAAACTCCTAGCCTCAGGTGATCCACCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACAGCACCCTGGTGAGCACTAGAGCTTATTTCTTCTATCTAACTGTATTTTTGTATCCATTAGCCACCCTCTTTTCATCCTCCCCTCTCCTTCCCTTCCCAGCCTCTGGTAACCACTGTCTGCTCTCTACTTCCATGACATATGCTTTGTTTTAGCTCTCACATATGAGTGAGAGCATGCGACATTTATCTTTCTGGCCCTGGCACATTTTTGAATCATTGTTAGAAAAGATGATGGTTTGGAGTAGATACATCAGAAGTGACAGCGTTTGCCCTAAAAAGGAAAGACAGGCTCCTCTGGGACCCTGACCAAGTTCCTGTGAACTATTTTATTATTGTGCTGTGTTAGTCCTGGGGTCTTCCGTTCCCAGCCCTCCTCACCTGCTCCCATATGGCTCTCTCTCTTCTTCCAACCTCTCAG
Seq C2 exon
GATGTCCTATGAGGATTTCATCTACCATTTCACAAAGTTGGAGATCTGCAACCTCACGGCCGATGCTCTGCAGTCTGACAAGCTTCAGACCTGGACAGTGTCTGTGAACGAGGGCCGCTGGGTACGGGGTTGCTCTGCCGGAGGCTGCCGCAACTTCCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000092529-CAPN3:NM_024344:9
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0064816=Peptidase_C2=FE(17.6=100)
A:
NA
C2:
PF0064816=Peptidase_C2=PD(12.8=34.5),PF0106717=Calpain_III=PU(15.5=43.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)