HsaINT0028675 @ hg19
Intron Retention
Gene
ENSG00000137944 | CCBL2
Description
cysteine conjugate-beta lyase 2 [Source:HGNC Symbol;Acc:33238]
Coordinates
chr1:89414774-89418835:-
Coord C1 exon
chr1:89418746-89418835
Coord A exon
chr1:89414961-89418745
Coord C2 exon
chr1:89414774-89414960
Length
3785 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGT
5' ss Score
10.86
3' ss Seq
TTTTGATTCTTAACAAACAGGAA
3' ss Score
7.18
Exon sequences
Seq C1 exon
CTTGGCTGGTCCATTGGTCCAAATCATTTGATAAAACATTTACAGACAGTTCAACAAAACACGATTTATACTTGTGCAACTCCTTTACAG
Seq A exon
GTAAGTGTTATAGTAACTCAGGGTAGAAGCATTGTCTTTTGGTGAAGGTATTACTTTTATATTGCATATTTGAATTGACTTAATTCTCCTTCTATCCTTCTGTTGCAGGGCCTTCTAATATAATTTGGAATTTGGGGAGCAGATACATATTCACTGTTATCAAGCATGGTTTGGGTTTTTTTTTAAACACAATTTTAGCTGTGTTAAACATTGCTGGCAGGAATCTAAAGTGCTACAAATTCTGTGAAGGACAATGGCAACACCAAACAAAATTACACATGTGTTTGCCCCATGAAAGCAATCCATCTTCTAAGAATTTACCCTAAAGTTGTGTTTTAGTCCGTTCTTGCACTTAGGTAAAGAAATACCTGAGACTTAGTAATTTATAAAGAAAAGAGGTTTACTTGGCTCATGGTTCTACAGGCTGTACAGAAAGCATAGTGGCTTCTGCTTCTGGAGAGGCCTTAGAAAACTTACAATAATGGTGGAAGGCAAAGAGGGAGTAGGCATGTCTCACAGGGCTGGAGCAGGAGGGAGAGAAGTGGGGAGGTGCAACACACTTTTAAACAACCGTATCTCACAATAACTCACTCTCATGAGAACAGCATCAAGGGGATGGTGCTAAACCATTCATGAGAAACCACTCCCATGATCCAATCACCTCCCACCAGGCCCCACCTCCAACATTGAGGATTACAACTGGACACTAGATTTGGATGAAGACACAGATCCAAACCATATCAAGCTATCTGCACATGTAAGAAGTTACGTACTTACCTGGCTATTCATTGCAGATGATTGAGGAGAATCCATTATCATCTACAGACGATTGATTACATAAACCATGATCTATCCAAACATTGAAATGTTATATGACCATATTAAGTTTCCTACTGGTGCTATAACAAATTACCACAAACTTAGTGACTTAAAACAACACAAATTTATTATCCTACGGTTCTTCAGCTCAGAAGTCAGAAATGGGTCTTAAAGGGCTAAAATCAAGGTGCTGGCATTGCTGTGTTCCTTCTGAAGGCTCTAGGAGAGTCTGTCCTCTGCTTCCGTCAACACATTTCCTGTGGCTTCAACCCTCCTGCCTCCCTTTTTCCCTTATAAGCACCTTTGAGATAACATTGGGCCCAATGGATAATCTGTCCAATTAATTAAGGATAATCTCCTTAATTTCAATCACATCTGCAAAGTTCCTTTCACCATGCAAGGTAACATATTTACAAGTTCTGGGTTTTAAGACCTAGAAGTCATTGGGACCCATTACTCTGTCTACTGGCTGCTAAAGAGAAAAGAAACAAGAAAGAAAATAGGGAAATACTATAATTACTGTACTGAGATAAAAAAGATTTCTAGAATACATCATAAAGTAAAAAAGAAAAACTATTTAAATATTATTTAATATTTAATATTTTTAATATATATTATGGAAATAGGGATTTAGTTACCATCATTCTATGGATAATCAAAATGCTGAAAAAAATAGTATTTTTCTAGAAGGCAGTTAAAAGGGCAAAAGAACCAGGCACAATGGCTCACGCCTATAATCCCAACACTTTGGGAGGCCAAGGTGAGCGGATCACCTGAGGCCAGGAGTTCGAGACCAGCCTGGCCAACATGGCAAAACCCTGTCTCTACTAAAAGTACAAAAATTAGCTGGGCATGGTGGCAGGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCCTGAATCCAGGAGACAGAGGTTGCAGTGAGCTGAGATCGTGTCACTACACTCCAGCCTGGGCAACAACAGCAAGACTTCGTCTCAAAAAAAAAAAAGAAAAGAAAGAAAAAAAAGATGTTGATAGATATGAAGAAGAAAGATAAAATAGGGAAGAGGAAGGATATAAAGCTCCAGGTGGGAGATATACAGTGTTAAATAGGGTAATCTTTGAAAGCCTCCCTGATAAGGTAACATTTGAACAACTAACTGAAGGGGATTAAGCAGCCACATGGTTACCTAGAGAAAAACCCCTTTGGACAGAGAGAACAAGCGGAAAGGCCCAGTGGTAGACAGCCTGGCTGGCATGTTAATATCAGAGAACAGCACAGAGACTGGAATGGAATGATTGAGAGAAGAGTAGGAAAAGCTAAGATCAGAGAGGTAGCTGGGAGTCCAATGGAGCTGGGGCATGCATGTCACTGTAAGGACTGAGTGAGATAGGAAGTCACTAGAGAGTTTTGAACTCAGGAGTGACTTGGTCTGGCTTGTGTTAGCAAATGGACTCTGACTGCCTCATTGAGTGAGAAAGCTGTTACAGTGATCCAAGAGAGAAATGCCAGTGCATTGAACAAAGATGGGGGTGGTAGAAGCAGTAAAAAGTGATTGGACTCTGAATATATTTTGAAAGTAGAGCCAACATTATTTGTCAATAGGTTACATATGGGATATGTGAAAAAGAAAGGAGTCCAGGATAATGCTGTAGTTAGGATGGATGTTTATGTCTCCTTATACTTGGAATTTTCTAAGGCAGTATCTCCTATAGTAAATGAACAAGTTGCCAAGAGAAAAAAAAAAAAAGATATAGCTAAGAATGCAGAACATCTTTTTCTGAACACTCTTATTCTCCATTTCAGCTAGGTGCTCTGTTTTGTCCTGGGACAACCATGTTTGGTTCCAGGAAACCACAGATTTCCAGGCTAAGGCAATCGATCCTTATTTTCCAAGATTTTGTAGTACTGGAGATTTATTACTAATTCTGTTTTACTGCATTCTTTTGGCATAAAATCTCTGTGATCTTGCCCCTCTCTGTCTCCAGTCTCATCTCTTGCCACACAGTCTCTCTTACCTGCCTGGTCCTTAATGTCTTAGTTGGACTGGGTGGCTTATAAACAACAGAAATTTATTTCTCACTGTTCTGGAGGCAGCAAAGTCCAAGATAAGGCACCAGCAGATTTGGTGTCTGGTGGGGACATGCTTCTTCACGGATGGTGCCTTTTGCTGTGTCCTTACATGGTGGAAGGAGCAAGCTAACCCTCCTTTGTAAGGGCACTAATCCTGTTCCTGAGGGCTCTACCCTTCTGTCCTAATCACTTCCTAAAGGCCCCACCTCCTAATACCATCACCTTGGGGTTTACTATTTTAATATATGAATATGAGAGTGGGCACAAACATTCAGTCCACTATACTTAACAACATTGGCTTTTTCCTTGGCCCAGTTTGCTGTCCTGGCTCTTGAAGAAAGATAGAGGAATTACTGTAGATGTTCCAGAAACTCATTTCTAGTCCCTCTTACACTTTGACCAACTTCCTGGCATATGAATAATTCCAGCAAGGATTTCCACACCTATGGAGAATAAGAAAGGCACATTTCTCCTTTGCACAGTAGGTGAGCTTTCATTTCCACTCTGTCCCCAAATGTAATGGTGAGAGGCTGACTACTCTCTGGTTGTTCTTCTGACTTAGATTTAGCAAGTCATTCTACAACTCACCTCAGCAGAAAATATCTTAATGTCTTTTTGTTTCCAAGCAAGCCACCTTTAAGTAACAGCTCTTTTTCAATTTGAATTTTCAGGACTCCTTCTCAGTTCTTCACATGAGATTTAATCATTTAGGTATAACTGATTCCTCCATTAACCTATAGAGTTTAATATAGGTTCACAGGAATTCAACTGTTATTTCCTGAGTGACTTCTTTGCCAATAATTTTACTCAGATCATCTCTATTTATTATACCAATAAACTAAGCAATAAATAACATTGCCATATGCCTTTTCATATTTTTTGATTCTTAACAAACAG
Seq C2 exon
GAAGCCTTGGCTCAAGCTTTCTGGATTGACATCAAGCGCATGGATGACCCAGAATGTTACTTTAATTCTTTGCCAAAAGAGTTAGAAGTAAAAAGAGATCGGATGGTACGTTTACTTGAAAGTGTTGGCCTAAAACCCATAGTTCCTGATGGAGGATACTTCATCATCGCTGATGTGTCTTTGCTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137944-CCBL2:NM_001008661:10
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0015516=Aminotran_1_2=FE(11.0=100)
A:
NA
C2:
PF0015516=Aminotran_1_2=FE(16.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)