HsaINT0041099 @ hg19
Intron Retention
Gene
ENSG00000121898 | CPXM2
Description
carboxypeptidase X (M14 family), member 2 [Source:HGNC Symbol;Acc:26977]
Coordinates
chr10:125526489-125528238:-
Coord C1 exon
chr10:125528042-125528238
Coord A exon
chr10:125526669-125528041
Coord C2 exon
chr10:125526489-125526668
Length
1373 bp
Sequences
Splice sites
5' ss Seq
GGGGTAATG
5' ss Score
4.85
3' ss Seq
ACACTCTCACTTGTCTCCAGGGC
3' ss Score
8.95
Exon sequences
Seq C1 exon
GTGAGCCCGAGTTCCACTACATCGCGGGGGCCCACGGCAATGAGGTGCTGGGCCGGGAGCTGCTGCTGCTGCTGGTGCAGTTCGTGTGTCAGGAGTACTTGGCCCGGAATGCGCGCATCGTCCACCTGGTGGAGGAGACGCGGATTCACGTCCTCCCCTCCCTCAACCCCGATGGCTACGAGAAGGCCTACGAAGGG
Seq A exon
GTAATGGCCCTGGCCCATCTCACCCAATAGGACATGGGCAGCGAGGCCCCAGCTCCAGAGTATGTCTGGCCCTAGGGCTATGCAAAATTCCACCTTCCGAGCTTTATTTATTTATTTATTTATTTATTTATTTATTTATTTATTTATTTTTTGAGTCGGAGTCTCCCTCTGTTGCCCAGGCTGGAGTACAGTGGCGTGATCTCCGCTCACTGCAACCTCTGCCTCCTGGATTCAAGCGATTTGCCTCAGCCTCCTAAGTAGCTGGGATTACGGCCGCCAGCCACCATGCCCAGCTAATTTTTGTATTTTTAGTAGAGAGGAGGTTGGCCAGGCTGGTCTCAAACTCGTGACCTAAGGTAATCCGCCAGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTAAGCCACCGTGCCTGGCCACACGAGTTTTATTTTTGAGTGTCTCTGCTGAGGCAGGGAAGCCTACAAGGTTTATGAAAAGTGCAAAGCAGGCATTGAGAATGATGGTGGCCTTGAGAGGTGGACATGCCGACCAACTGGAGGACGTGAAGATGAACATCAATATTGCTATATACACAATGATAATGGAATCCAATAGTAACACTTTATGTTGGCTGAGGACTTAATCATGGCATGTGTTAGCCTTGATTATTACCTTTAATCTTCTCATCAGTCTTCTGAGGATAGTTGTTTTATTATTCTGATACGTTCTTTACATTTTGTGTTCCAGTTATGATATAGAATGTATATAGGTTATAGGTGTGCATAGAATATGCATATGTACAGAATTATGTATAAATAGAACATATAGTTAGTATTATGTTGTGTTGTGTATTGACAGTGATATATCTCAATACCTGGGAATAAAATGGAAAATTATATTAAAACAAGGGTACCTATCAAATGCAAGCTTTACAGTATAGAAATGTGGTCACATTTATTGGTGCAGATATAGTCAGTTAGGAATTTGCATTGCTAAATAGTGAGCCAGAATCATGGGCAGGCAGGGAGAATGCATTACTGTGGTGGCCATTGATGAGTTCATTGCTACTCAGAGGTTCACCTGGCCAGTATAGAAGAGAGGAAGGTAGGGGTGGAAGAAGGAACCTAATGCTTTTTAAGCACTTCCATGTGGCAGGGGTGGTTCTCTGCATTCCCTCTTTGGAGTAATTTGGCTGAACTATCTATCACCCACCAAATATTAATAGGAAGTTTTTCAATATTCTCCTTTAGATGCCATCTTTGGGTCAAAGGGCATCTAGAGGCTTAGAGACATTCCCCAAGGGGAAGTGGAGACAGATGCATCTTGTATGGTAGAGGGTCCGCGTTGTCCTGCAGCCTGTGCATTCTTCACACTCTCACTTGTCTCCAG
Seq C2 exon
GGCTCGGAGCTGGGAGGCTGGTCCCTGGGACGCTGGACCCACGATGGAATTGACATCAACAACAACTTTCCTGATTTAAACACGCTGCTCTGGGAGGCAGAGGATCGACAGAATGTCCCCAGGAAAGTTCCCAATCACTATATTGCAATCCCTGAGTGGTTTCTGTCGGAAAATGCCACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000121898-CPXM2:NM_198148:9
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.045 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0024619=Peptidase_M14=FE(21.0=100)
A:
NA
C2:
PF0024619=Peptidase_M14=FE(19.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGTTCCACTACATCGCGGG
R:
CCGACAGAAACCACTCAGGGA
Band lengths:
358-1731
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)