HsaINT0041350 @ hg38
Intron Retention
Gene
ENSG00000005339 | CREBBP
Description
CREB binding protein [Source:HGNC Symbol;Acc:HGNC:2348]
Coordinates
chr16:3757288-3758048:-
Coord C1 exon
chr16:3757809-3758048
Coord A exon
chr16:3757377-3757808
Coord C2 exon
chr16:3757288-3757376
Length
432 bp
Sequences
Splice sites
5' ss Seq
AAGGTACAG
5' ss Score
8.04
3' ss Seq
TTTCTCCTTTATTTTTGCAGTAT
3' ss Score
9.28
Exon sequences
Seq C1 exon
GACTATTTTGACATCGTAAAGAATCCCATGGACCTCTCCACCATCAAGCGGAAGCTGGACACAGGGCAATACCAAGAGCCCTGGCAGTACGTGGACGACGTCTGGCTCATGTTCAACAATGCCTGGCTCTATAATCGCAAGACATCCCGAGTCTATAAGTTTTGCAGTAAGCTTGCAGAGGTCTTTGAGCAGGAAATTGACCCTGTCATGCAGTCCCTTGGATATTGCTGTGGACGCAAG
Seq A exon
GTACAGTTTTAAGTTTTTCCGGAAAGTGAATTTTCCTGGTTAATCCAGCCAGAGGGGTGTTATACTAATATGAGACCACGCCTGTATACTGGGAGTGCATATGTGCAATCTGCTGTCTGGTGACACAGTTGATGCCTGAAGCGATGTGATGGGTGATCAGAGCTGGGTGTACAGGCGCTTACTGAGGGAGGCCATGGGGAAGCGTTTCTGGCTGCCCCTCTCTGCCTGTGGTACCTGTCTGTAGTGAATGTCTCTTAGAGCCAGTTCTATCACATGCTATCCCAAAATGTCTTTAAAGCTACTAAAATTGTTAGAAAACTGTCTAATATACTAACAGAAATAATTTACTAGTCTCTATAGTAGACTAGAACATTATAAGACAGTAAATGGAATGTATTTTTATATAAAAGTATTTCTCCTTTATTTTTGCAG
Seq C2 exon
TATGAGTTTTCCCCACAGACTTTGTGCTGCTATGGGAAGCAGCTGTGTACCATTCCTCGCGATGCTGCCTACTACAGCTATCAGAATAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000005339:ENST00000262367:18
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.013 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0043920=Bromodomain=PD(64.4=70.0),PF060018=DUF902=PU(28.6=15.0)
A:
NA
C2:
PF060018=DUF902=PD(66.7=93.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTATTTTGACATCGTAAAGAATCCC
R:
ATTCTGATAGCTGTAGTAGGCAG
Band lengths:
326-758
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development