MmuINT0042140 @ mm10
Intron Retention
Gene
ENSMUSG00000022521 | Crebbp
Description
CREB binding protein [Source:MGI Symbol;Acc:MGI:1098280]
Coordinates
chr16:4107428-4108275:-
Coord C1 exon
chr16:4108036-4108275
Coord A exon
chr16:4107517-4108035
Coord C2 exon
chr16:4107428-4107516
Length
519 bp
Sequences
Splice sites
5' ss Seq
AAGGTATAG
5' ss Score
7.98
3' ss Seq
TTTTCTTCTTGTTTTTGCAGTAT
3' ss Score
10.08
Exon sequences
Seq C1 exon
GATTATTTTGATATAGTGAAGAATCCTATGGACCTTTCTACCATCAAACGAAAGCTGGACACAGGGCAATATCAAGAACCCTGGCAGTATGTGGATGATGTCTGGCTTATGTTCAACAATGCGTGGCTATATAATCGTAAAACGTCCCGTGTATATAAATTTTGCAGTAAACTTGCAGAGGTCTTTGAACAAGAAATTGACCCTGTCATGCAGTCTCTTGGATATTGCTGTGGACGAAAG
Seq A exon
GTATAGTATTTCTGGAAATTCTACTTTTCTGTCTGATCCAGCCAAGTCAGTGTTGGAAGTCTAGGGCATACTGCCTTTGGGTTTTTTAGGTATTGTATTTTGGTGTTTTGAGACAGGTTTTCTCTATGTTGTCCTTGGCTATTCTGGAGCTGGCCTTGAACTCAAAGAGATCTCCCTGCCTTTGCCTCCCAAGTGCTGGGACTAAAGGTGTGTACCACCACTGGCTGGCTAGTGTGGTCTTTCTAACAGTTGACTTCCTGACATGATGTCATGGTCAAAGTAAAAGGAACTCACTGGGAAGGCTGACTGCCCTGTGCCCATTGTATCTGTACCTGAAACCAGAGCTACACCAATTCTGTCACATTAAGTCCAAAAATGTCCTGAAAATAGTTATGAACATTGTTAGAATTTAATCTTGTGTTCTAGTTAATAACTAGTTCGGTCTTTTGCCATCATATGCTAGAATACTTAGGGGTGGTAATTGAATATATGGTTAGTATTTTCTTCTTGTTTTTGCAG
Seq C2 exon
TATGAGTTCTCCCCACAGACTTTGTGCTGTTACGGAAAGCAGCTGTGTACAATTCCTCGTGATGCAGCCTACTACAGCTATCAGAATAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000022521:ENSMUST00000023165:18
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.013 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0043920=Bromodomain=PD(64.4=70.0),PF060018=DUF902=PU(28.6=15.0)
A:
NA
C2:
PF060018=DUF902=PD(66.7=93.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGATATAGTGAAGAATCCTATGGACC
R:
TTCTGATAGCTGTAGTAGGCTGCA
Band lengths:
318-837
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types