HsaINT0041355 @ hg19
Intron Retention
Gene
ENSG00000005339 | CREBBP
Description
CREB binding protein [Source:HGNC Symbol;Acc:2348]
Coordinates
chr16:3794895-3795355:-
Coord C1 exon
chr16:3795278-3795355
Coord A exon
chr16:3794963-3795277
Coord C2 exon
chr16:3794895-3794962
Length
315 bp
Sequences
Splice sites
5' ss Seq
AGGGTGAGT
5' ss Score
9.25
3' ss Seq
ATACCACTATTATTTTGCAGTTT
3' ss Score
7.25
Exon sequences
Seq C1 exon
TTTCGTTGATTGCAAGGAGTGTGGCCGGAAGATGCATCAGATTTGCGTTCTGCACTATGACATCATTTGGCCTTCAGG
Seq A exon
GTGAGTTGTTTCCCCTGGCCTGGAGGGCAGTTCTGCACAGAGCCAGTGGCGGGGCAGTTGCAGTGGCTACTGCATCTCATTCATTGTTGTCAGCAAGAATTCAGCGATTAAGAGAGATGGCAGTTGGTTCTAAATTTAAGTTCTAAGCGTTTGTCCGCTTTAGGAATTGTGGAATCAAAGCAGTCTGCCTCTTCACTCTTTAATTTTATAATAATGTGATTTAAACTGCCAACAAACTATCTGAATGCTGCATTTTGTTGGTTTGACAATTTACATCATTATATACAGTCTCATCATACCACTATTATTTTGCAG
Seq C2 exon
TTTTGTGTGCGACAACTGCTTGAAGAAAACTGGCAGACCTCGAAAAGAAAACAAATTCAGTGCTAAGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000005339-CREBBP:NM_004380:22
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.250
Domain overlap (PFAM):
C1:
PF0062824=PHD=FE(55.3=100),PF127602=Zn_Tnp_IS1595=PU(27.3=33.3)
A:
NA
C2:
PF0062824=PHD=PD(19.1=37.5),PF127602=Zn_Tnp_IS1595=FE(69.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)