HsaINT0044110 @ hg38
Intron Retention
Gene
ENSG00000148795 | CYP17A1
Description
cytochrome P450 family 17 subfamily A member 1 [Source:HGNC Symbol;Acc:HGNC:2593]
Coordinates
chr10:102832511-102833208:-
Coord C1 exon
chr10:102832993-102833208
Coord A exon
chr10:102832681-102832992
Coord C2 exon
chr10:102832511-102832680
Length
312 bp
Sequences
Splice sites
5' ss Seq
CAGGTGTGC
5' ss Score
6.46
3' ss Seq
CAACCTACTCTGGTCTTCAGGTG
3' ss Score
7.09
Exon sequences
Seq C1 exon
GAGAAATTCCGGAGTGACTCTATCACCAACATGCTGGACACACTGATGCAAGCCAAGATGAACTCAGATAATGGCAATGCTGGCCCAGATCAAGACTCAGAGCTGCTTTCAGATAACCACATTCTCACCACCATAGGGGACATCTTTGGGGCTGGCGTGGAGACCACCACCTCTGTGGTTAAATGGACCCTGGCCTTCCTGCTGCACAATCCTCAG
Seq A exon
GTGTGCTTCCCCCTCATTGATCCTAGACCCCAGCCAGCCCAATCTCTGGGCTCCAGAGAAAGGGAGAGCCAATTCTCTCAGGCTTTCTGTGCAGGAAGACTAGGCCTGCCCTGCTCCTTACCCAAGCAGTAGTTGGCTTTGACCCCAGAGTAGAGCTGCCCCATCTTCTGGAAGCCGGGCCTGGGCCCCAGAGCCACTACTGGGAAGGGACTGGACAGGCTCTTCTCGATGTCACAGTTGGATTCTTCTCTAAGCCCTTGCTTCTCCTGGGCTTACACACACTAGTCACCTCCAACCTACTCTGGTCTTCAG
Seq C2 exon
GTGAAGAAGAAGCTCTACGAGGAGATTGACCAGAATGTGGGTTTCAGCCGCACACCAACTATCAGTGACCGTAACCGTCTCCTCCTGCTGGAGGCCACCATCCGAGAGGTGCTTCGCCTCAGGCCCGTGGCCCCTATGCTCATCCCCCACAAGGCCAACGTTGACTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000148795:ENST00000369887:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.222 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006717=p450=PD(9.9=11.1),PF0006717=p450=PU(29.3=98.6)
A:
NA
C2:
PF0006717=p450=PD(0.5=1.8),PF0006717=p450=FE(32.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCACCAACATGCTGGACACAC
R:
TTGTGGGGGATGAGCATAGGG
Band lengths:
346-658
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development