HsaINT0046680 @ hg19
Intron Retention
Gene
ENSG00000119522 | DENND1A
Description
DENN/MADD domain containing 1A [Source:HGNC Symbol;Acc:29324]
Coordinates
chr9:126212972-126214626:-
Coord C1 exon
chr9:126214555-126214626
Coord A exon
chr9:126213029-126214554
Coord C2 exon
chr9:126212972-126213028
Length
1526 bp
Sequences
Splice sites
5' ss Seq
TTCGTAAGT
5' ss Score
9.77
3' ss Seq
TAAATTAATTTTTCATGCAGGCA
3' ss Score
6.41
Exon sequences
Seq C1 exon
AAAGGAAGTGGAGCAATTCTGAATACTGTAAAGACCAAAGCAAATCCGGCCATGAAGACTGTCTACAAGTTC
Seq A exon
GTAAGTACTGGTCTTGCTGTCAGGAGCCAAAACAGATCAGTCCCTTAGCATGATGAGACTCTTTATTTATTTACTTACTTTTGAAACTGGGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCAATCACAGCTCACTGAGGCCTTGACCTCCAGGGCTCAAGCAATCCTCCCACCTCAGCCTCCCCAGTAGCTAGGACTACAGGTGTGCACCACCACGCCTGGCTTTTTTTTTTTTTTGGAGAGACAGGTCTCAGTATGTTACCCAGGCTGGTCTTGAACTCCTGGGCTCAAGCAATCCTCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACCAGCATGAGCTGCTGCACCCAGCCAAGCGATGAGACTCTTAAGTATACCTTGTCCTCTATTGCAGAGATGACTCAGGCTGCTGAGCTCTTTCCTGAAGGTCTCAATGTTCTTCAAATTATTTAGCAGATTATTATAACTGGTTCAGTGACATTTTTAATTTATAGTGTTGGTGCTCACATTTGCCACAGTAGAGAAATGGGAGGCTACTGGTTTTAGCTTTTAAAATGTAGACTAGGTGGCTGCACCCTGCCTCTGTTTCTGAGACCCGGAAGCATGGTCTATCTGGTGTCTGGCAAAGCCTTCCTGCAGGAATCCCCATTATTGGGTCAAAATAAAGCAGCTCCTTTGCAGTTTCCTGAAGCGTGTTCGTGGTGGCATACACCACTTAATTTTTGTCCCAAATTCTTCATCATCTCTCTGATCACTGCCCTATAGGAAATGCATTATTTGTAAGACTCGTGTCCACAGCGGAGTGAAAATAGGAGAGCACATCTGTTCCCGGTGCTTCATCTTTCACAAGCATCAAGTATTTTTTCTTGTGACTTCTCTTGCTTGCTAATTTGACCGTGAGCCACTGAAGCGGGGTGGTTTTATTTTATTTCCATTTTTAATTTTGTTAGTCCTCTCTGTGCTTAAGCTGTAGTTATTTTAGCAGGATGGGTGGCTGCCAGCAGAACCACACAGGTCTAAAATGACCTGAAATCAAAGCCAGGGTGTCTGCCAAAATGAGATTTAGGAAATGGCACTGTAGAAACCCAGCAATGTGTCTGTTCCGGCCATTCAGCCTGGGCAGAAAATTGGTCCTGGGGCCCTGCCCTGGTGAAATAGAATGGATATTCTGAATCTTCCAGCCAGAAATACGGCTGCCGTACTCTTACTGGTAGCTGTCACCAGGCTGCTGAGATAAATAATTATAGAGAGCAGAAGAAGGGCTTTGGAACGGAAAGAAAAAAAAAATCTGTGCCATCAAAATGCAGAAAATAAAATCTCTGCAGCCTCTTTAAGGGTTTTTTTTTAACCTTTTACCGTTGTATTTGTTTTCATAGCCATTATGTTTTCGACTTGATGATCCCATTTTTCCTTCCTTTTTCTAGTAATCAGAGAAGGTGATTCTCGATGGACTGAAATCAAGCATAGTCCCTGCTGGAAACAGAAAGGGAATCTTAACTTAAATTAATTTTTCATGCAG
Seq C2 exon
GCAAAAGATCATGCAAAAATGGGAATAAAAGAGGTGAAAAACCGCTTGAAGCAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119522-DENND1A:NM_020946:17
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.157 A=NA C2=0.362
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)