HsaINT0048144 @ hg19
Intron Retention
Gene
ENSG00000066084 | DIP2B
Description
DIP2 disco-interacting protein 2 homolog B (Drosophila) [Source:HGNC Symbol;Acc:29284]
Coordinates
chr12:51064969-51068412:+
Coord C1 exon
chr12:51064969-51065181
Coord A exon
chr12:51065182-51068256
Coord C2 exon
chr12:51068257-51068412
Length
3075 bp
Sequences
Splice sites
5' ss Seq
TAGGTAGGA
5' ss Score
7
3' ss Seq
ACTTTGTTTTCTCCTCTCAGAGA
3' ss Score
10.39
Exon sequences
Seq C1 exon
ACACATCTTCGGCCTCTGAGGATGAGGGCTCTCTGAGACGCCAAGCTGCGCTCTCTGCTGCCTTGCAACAGAGCTTACAGAATGCTGAGTCCTGGATCAACCGTTCAATTCAGGGATCGTCCACTTCTTCATCCGCATCTTCTACGCTGTCCCACGGAGAGGTCAAAGGAACCAGTGGGTCTCTAGCTGATGTATTTGCCAATACTCGAATAG
Seq A exon
GTAGGAGCTGGATCTACCCAAGAAGCCCAAATTACATTCCATTTGGCTCCCAGTATCCAGGAAATAGTTTATGGTTTGTGTTAGGTTTTTCAGTATGGCCTAAAAAAAAGAATTAGAGAAAACATGACAGTTAATGAGGAAAAGATGGAAACACCAGCAATACATTTGTCACAGGAATAATAGATAACACCTGCATTATTGGTGCGTAGTTTTGCCCACCTGAAGCCATAGCTATTTCCATAAGCAATGCTCAAGCTGCAAGATATAACACCAGTCTCAGTGTGGAGTTATCCCAGCTGAAGAATATTCGATCTATTAAAAGGTTAAAATATGTAACATCTTAGATTTTTCCCAGGATTGTTACCTATATTCTGTTAAACCAAAAACACTAAACCTGAGCAAAATCTATACTGAGCCAATATCAGTGAGGACTTTTGTCTTGACTGGATTTGTTGTCCTTGCTGCTGTGATATTGCTACACTGGAGTGTGCAGGCCGAGGATATTGGTACTCTGAGCTGCTATCGATACACTGCAGATGCTACTATACAGAGTGTAGCTTTTGCTTGCCCCTGCTTTATGTTTTGTGTGTGTGTTTTTTTAAAGAGTTGTGACATCTGCAGATAAAGATACAGCTCAGATCTCTGCTTTTGCTTAATTGGTTGTTACAAATTACACCAAGTAATGTGTGTTAACATTATGTGTCTGTGATATCTTTCCCTTTTTTTTCTTGACAATCAGTGCATTTTGGTGTCTTAATTTTCATCTCAGTGACCTGTCTATATCACCTAATATATCTTTATTCTGTTAACTGATTTCTAAAAAAAGAAAAACTTGGAAAAATTTCAATTCAAGACTATAATTTTTAAAGAAATAGCTACCTTGAGGGTATGATTGCCCTCCTTAGAGACCCATGTGCCAACAGCTGATGACTTGTCTTGCACGCTTAGCTCTGCCCTGCCCTGCCATTTCCTGAGCCTCCTGAAGCAGCTACAAAGATTTGCGTATTCACCACCTCTCCAGTCGTGGAGCAACAGAGCCATGGTTGCTGAGGTTTTATTTCCACATCTGTCTAAAAGAGACCAGTATTACTTGTTAAATATATTATCCTAATACCCAGTTAACTTTTACCTGGATTTTTGTTAACAAGATGTCTCATCCAACCGTATATTTTTCATTGCTTCTACTACTCTGTGAAAAGTTACTGGTTCAGTTACTCACAGAAACCATTTTATCCACATTATTGCTTTTTGGATGTTTGTTGTAACAGGAGTAATTCATGATCCTAATAGAAAAATTCAAAAATATAGGTAAAAGAAAAGTAAAATAACCTATAATCCTACCTCCCATGGGTAATACTTTAGTATTATTACTGTAGTGTATATTCTTCTAGATTTTACTTACATATGTAAGGTTTTGGTTTTGATTTTACAAAAATGAACTGTCCTAAACATAATGTTAATAACCTGCTTTTCTTAGCAGTATGTGATGAACATCTTTTACATCATTATGTTACACTATTATTTTTATGGTTTCAATATACACTATTGTGTGACTCTCTGCCCTGGTTTATTTGGCCATTCCCCTATTAAATAGTGTCCAATTTTTTGCTATTATAAAAACTATTGGATTGAACATGCTTGAACACACAACTTTGTACATTTGTCTGATTATTTCCTTAGCGTATATTCCTATAAGTTTGAATTGCTGGACCAAATAAAAATGTCTGTTTTAATGCTTTTTGTTACCACATTATCCTACAGAAAGGTATACCGGAATATACTCATGTTAGTATATTTAAAATTTTAAAAACTATTCAACTAATAATTACAGACTTAAGGGGCATAGAGACCTTACCCCCAAATCTATTTTAGAAATTGTTTGTATTATGCTTTTTTCCTTTTTTAAGTTTTACAAAAAACTTAGAAGAAAACATCTGGAGAAGTAAGAAGAAGGAAATTAGAGGGAGGAAAATGTATGATTTACAAGAATCACAGAAAGCCACTAAAAAACTATGTGGTGTTTTTTGTTGTTGTCGTTACGTGTCCCTGTTGAACAGGGATCTTTTCCAGTTTACTCATTCAGTTTCTCCATGTTAAGAATCTTGAGACCTGGTGTGGTGGCACACGCCTGTAATCCCAGCACTTTGGGAGGCATTGGTGGGAGGATTGCTTGAGCCCAGGAGTTCGAGACCAGCCTGGGCAGCATGGCAAGACTCCATCTCTACTAAAAATACAAATATTAGCCTGATGTAGTGGTGTGCACCTGTGGTCCCCATACTTGGGAGGCTGAGGTGGGAGGCTTACTTGAGCCCAGGAGGTTGAGGCTGTAGTGAGCTGTGATTGCACCACTGCATTCCTGGCTGGGCAACAGCACAAGACCCTGTCTGAAAAATAAAAAGAATCCCTATGTGCGGTAGAGTAGAATAACACTATTTAGTCTCTACCTGGAGCAAAGGAAGAACCTTGTCTGTCAAGGAGATCCAAATTACCTATGGATTATTGTATGATCCAAATTACCTATGGATTATTGTATAATCCGTAGGTAAAAGTTAAAAGTGGACTTTATCTAGTGTTTTTTCATCTGGAAACTTGTGCAGCCTGACCCACTTTCAAGATACGAGTTTGGTCTTTGGTAGAAGGGGAAACATTCTAGATAAACTATAACAATCAAGAAATGTTCGAGAGACTGCAATATTAGTAGCCAGTTATGATCTTATTTGGTTCCATTTTGAGGTCACTGCAAGTTTTATTATGATTATTTTATAACACTGGATTTCTACCAGCCTTTCTGTGTAGAAAATGATGTTTTGAGAAACATTGAATGTGAGATTTGATCTTACTAAGGCTACTCAAGTCTTACAAAATAATAATTTTGGAAAGCTGATATACCCTGGCTTAACTTACTGTTCTCCCATTGTGTCTTGCTAATAGATTCTGATTTTTAAATGTTGTTTTACAAGAGCCAGTGCCCCCATTTATGTACTTTTCTTCCTTGTTAAAAAACAAAACCCCAAAGATTTGAAGGTTCTTAGTTTTGCTGCTAATATAATTCTAAACTTTGTTTTCTCCTCTCAG
Seq C2 exon
AGAATTTCTCTGCTCCTCCTGATGTCACTACAACTACCTCTTCCTCCTCATCATCTTCCTCAATTCGCCCAGCAAACATTGACCTGCCCCCCTCGGGGATAGTTAAAGGCATGCACAAAGGATCCAACAGGTCCAGCCTTATGGATACAGCTGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000066084-DIP2B:NM_173602:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.907 A=NA C2=1.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)