HsaINT0049581 @ hg38
Intron Retention
Gene
ENSG00000187775 | DNAH17
Description
dynein axonemal heavy chain 17 [Source:HGNC Symbol;Acc:HGNC:2946]
Coordinates
chr17:78437641-78439217:-
Coord C1 exon
chr17:78439090-78439217
Coord A exon
chr17:78437869-78439089
Coord C2 exon
chr17:78437641-78437868
Length
1221 bp
Sequences
Splice sites
5' ss Seq
CAGGTACGA
5' ss Score
10.03
3' ss Seq
GCCTCTAGTCTTGGCTGCAGAAT
3' ss Score
3.56
Exon sequences
Seq C1 exon
GAAAAAAACTAGGGTTTACCATAGACAATGGAAAACTCCATAATGTGTCCCTGGGGCAGGGACAAGAGGTGGTGGCTGAGAACGCCCTGGACGTGGCTGCAGAGAAAGGACACTGGGTCATTCTGCAG
Seq A exon
GTACGAGGGGGCCAGCACTGCAGGGTAAGGGCTCCCCGCACTGAGGTGGCCAATGGGGATGGGCCAGAAGGCCCGGAAGGAAGCAGGATGTGGAGTTTGCATTCAGAAATGTGGGTGGAAATCCTAACACCACTGAAGGAGGAGGCATCCCCAGTGTCGGCTCTGCTGGGGTCAGCTGGGTGGTGTGGCACGCCATGACTGCCCAGAGGAAAGCGTGGATTCTTCAACGGTGAGAGGGAAGCTGGGCTTTATACGAGAGTACCCCAAACAGAGATTATTTAAACAACAGATGGTTGGGCACGGTGGCTCACACCTGTAGGCCCAGCACTTTGGGAGGCCAAGGCAGGCGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGCGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCAAGTGTGCTGGCACATGCCTGTAACCTCAACTACTTGGGAGGCTGAGGCAGGAAAATCGCTTGAACCCGGGGAGGCAGAGGTTGCAGTGAGCCAAGAGTGCACCACTGCACTCCAGCCCGGGCGACAGAGTGAGACTCCATCTCAAAAAAATAAAAAAAAAAGATGACAAGTGCTGGGTTGACAAAAGCATCTCCTCCTCCTCCTCCCTCCTCCCTCCTCCTCCTCCTCCTCCTTCTCCTCACTTGGGGCAGGCAGCAAAGCCCAGAGCGCCCAGGAGATGCTCTCTGCACATTTGGTTCAACGCTAGCACGACCACCCCTCCTCAGCCCTGGAGCCCATCCAAGACCCCTTCTCACTACCGCTTGTCCTCGAGCGCCTCTGGGCCTGTCCCAGCTTCCACGGGTCTTACAGTGTGTGTCGACCTCAATCCACAGGGCTAAGCCTGGCCCCGGTGGGAAGCCCTCAGCTTCAAGAGGAGGGGTGGGGACCACAGAATCTCAGCCTTATGCCAGGGAGGACACAAAGGACTCACCGTAAGGCTGGAGGTTTGCAATTCATTGAACACAAAAATAGATTCTGGGGCCTCAGTTGCTTCGCCGAAGACATCCTGGCATGCCCAGCACCTGGTTAGGGTGGACAGGTGAGGGGTGGGGCAGTGCCAGCACCAGGCAAGTGTGGGGTGCTGGCAGAAGAGCCCTGCCCTCACCAGGGAACATAGCCACGTGCCAGTCTCTCCTCGTGGGCCAGGAGCTGGGCAAAGTGTGTAACCAGCCTCTAGTCTTGGCTGCAG
Seq C2 exon
AATATCCACCTGGTGGCCCGGTGGCTGGGAACACTGGACAAGAAGCTGGAGCACTACAGCACGGGCAGCCATGAGGACTACCGGGTGTTCATCAGCGCGGAGCCTGCCCCCAGCCCCGAGACCCACATCATCCCCCAGGGCATTCTGGAGAACGCCATCAAGATCACCAACGAGCCCCCCACGGGCATGCACGCCAACTTGCACAAGGCCCTGGACCTGTTCACCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000187775:ENST00000585328:73
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.013
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(6.0=100)
A:
NA
C2:
PF0302810=Dynein_heavy=FE(10.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGAAAACTCCATAATGTGTCCCTG
R:
CTGGGTGAACAGGTCCAGGG
Band lengths:
328-1549
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development