HsaINT0050687 @ hg38
Intron Retention
Gene
ENSG00000079805 | DNM2
Description
dynamin 2 [Source:HGNC Symbol;Acc:HGNC:2974]
Coordinates
chr19:10795372-10796199:+
Coord C1 exon
chr19:10795372-10795439
Coord A exon
chr19:10795440-10796060
Coord C2 exon
chr19:10796061-10796199
Length
621 bp
Sequences
Splice sites
5' ss Seq
CAGGCAAGT
5' ss Score
3.1
3' ss Seq
CCGGGTCTGGACGGTTTCAGGAC
3' ss Score
5.77
Exon sequences
Seq C1 exon
ATGGAGTTTGACGAGAAGGACTTACGACGGGAGATCAGCTATGCCATTAAGAACATCCATGGAGTCAG
Seq A exon
GCAAGTTCCACGAGGAGAGTCACCACTGTTCCTTCCTCTCCGTGGTGCGACCCCCCAGCTAATTGGGTCACCCACACCTCTGAGTCCCTAATCGTTAGGCCTTAAGAGGGCTCTTGGATGGTTTTCTGTAGCTGCGAGCCCCTCCCTGAGGGTCTCCAAGGGCACATGAGGGTGGATGTGTCTTAGTCCTGCGTCCATTGCAGGCTTCAGGGCTGTCTGCAGCTCCTGATCAAATAGGGCTTAGTTCCTGCCCAGTCGGTTGGTGTGAACCTCATGCTAAACTAAGAATGCTCACTGCAGATTTGCCTGGGGAGGGGCGGGGCGGCACTGAATCAGGGTTTTGGGAAGCCAGCATGAGTCCCCATCATGGCTTCCTCGTGAGCCTCTTGGGTCCCCTCCTTATTCTAACAAAGGTAGTTGCTCCAGGTGTCTGCCCTTCCATCGCCGTGGGGTCCTCGGGTCACCCTGAGGGTTTCCGGGCAGTGGACTCAGGCATCCGACCCCACACATGACACAACCTTCATTCCTTGTTGGGGACCCGGCCAGGGCCAATGAAATTGCTGACCATGCTTTGTTTCTCTCTGACTTATCTCCCCTGCCCCCGGGTCTGGACGGTTTCAG
Seq C2 exon
GACCGGGCTTTTCACCCCGGACTTGGCATTCGAGGCCATTGTGAAAAAGCAGGTCGTCAAGCTGAAAGAGCCCTGTCTGAAATGTGTCGACCTGGTTATCCAGGAGCTAATCAATACAGTTAGGCAGTGTACCAGTAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000079805:ENST00000355667:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0103115=Dynamin_M=FE(7.5=100)
A:
NA
C2:
PF0103115=Dynamin_M=FE(15.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGAGTTTGACGAGAAGGACT
R:
CTTACTGGTACACTGCCTAACTGT
Band lengths:
206-827
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development