HsaINT0050699 @ hg38
Intron Retention
Gene
ENSG00000197959 | DNM3
Description
dynamin 3 [Source:HGNC Symbol;Acc:HGNC:29125]
Coordinates
chr1:172387133-172388809:+
Coord C1 exon
chr1:172387133-172387359
Coord A exon
chr1:172387360-172388572
Coord C2 exon
chr1:172388573-172388809
Length
1213 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
3' ss Seq
TGATTTCTCTTTTTCCTCAGGTC
3' ss Score
11.42
Exon sequences
Seq C1 exon
GTTAAAGATTTCATAAATTCCGAGCTCCTAGCACAGTTGTATTCTTCAGAGGACCAAAATACCCTGATGGAGGAATCTGCTGAGCAGGCTCAGCGCCGGGATGAGATGCTTCGAATGTATCAAGCACTGAAAGAAGCCCTTGGGATAATTGGGGACATCAGCACAGCCACCGTGTCCACTCCGGCACCCCCTCCAGTGGATGACTCCTGGATACAGCACTCTCGCAG
Seq A exon
GTAAGAAGATGGCCCCGGCCGGGTGCGGTGGCTCGCTCCTGTAATCCCAGCACTTTGAGAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCGAACATAGTGAAACCCTGTCTCTACTAAAAACATAAAAAAAATTAGCCGGGCGTGGTGGCGGGTGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGTGTGAACCCGGGAGGCAGAGCTTGCAGTGAGCCGAGATCGTGCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAGAAGATGGACCCACCCACAACCCCTGAGCCCTGCCACGCTTGTCCAATATCATTTTCTGAGAGTGCTTTCCTAAACCAAGATGGACCTACAGAAAAAGGGGAAAAGATATTTACATTCAGGAGTAAGGATCAGATTATACTAACTCCCTTAAAAATGCAGCACAGTGCATCCTCACAATGGAATGTTATATAGTCACTAAAAAGAACAAGACAGTTCTATTAAGTCCTAAAATGAAAAGATAATCCAGTTAACGGGAAGCTTTAAAAAAAAGGGAGGTTGTATGCCAGGCGCGGTGGCTCACGCCTGTATTCCCAGCACTTTGGGAGGCCGAGGCAAGCGGATCACCTAAGGTCAGGAGTTTGAGACCAGGCTGGCCAACATAGTGAAACCCTGTCCCTACTAAAAATACAAAAATTAGCTGGGGGTGGTGGCGCACACCTGTGATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAATTCAGGAGTCAGAGGTTGCAGTGAGCCGAGATCACGCCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCGCCTCAAAGAAAAAAAAAAGGAGGTTGTAGAAGACTGTGTTCTATGGTATACAGAAAAGCAATTTATATATAGAGAGAGAAAATATATACTTATACAAATGTAGAATACAGTTAAAAAGGATGCACAAGAAACTTCTATAGTTGTTTCAACAGAGTGAAGGGGTAGGGAGAGGAAAACTTACTTTTCTCCATTTACCCTTTTATCCCTTTGACTTTCATGACATGAATTGGACTTATTCAGTCAAAAAATAATTTTTAAAAAGCAGGAAGTTACAAAACATTTTTAGAGATTAATTCAGACAGAAAGGAGGAGTGAGCAAACTATGATTTCTCTTTTTCCTCAG
Seq C2 exon
GTCACCTCCTCCAAGCCCCACAACCCAAAGGAGGCCAACACTAAGTGCTCCCCTCGCAAGGCCCACATCCGGCCGAGGACCAGCTCCTGCCATTCCCTCTCCTGGCCCCCACTCTGGGGCTCCTCCAGTCCCATTCCGTCCAGGCCCATTACCTCCTTTCCCCAGCAGCAGTGACTCCTTCGGAGCCCCTCCACAAGTTCCATCTAGGCCTACGAGGGCCCCGCCCAGTGTCCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197959:ENST00000367731:18
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.641 A=NA C2=1.000
Domain overlap (PFAM):
C1:
PF0221213=GED=PD(56.5=68.4)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCGGGATGAGATGCTTCGAAT
R:
CCCTCGTAGGCCTAGATGGAA
Band lengths:
350-1563
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development