HsaINT0051458 @ hg19
Intron Retention
Gene
ENSG00000147443 | DOK2
Description
docking protein 2, 56kDa [Source:HGNC Symbol;Acc:2991]
Coordinates
chr8:21768184-21769499:-
Coord C1 exon
chr8:21769412-21769499
Coord A exon
chr8:21768369-21769411
Coord C2 exon
chr8:21768184-21768368
Length
1043 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
CTCTCTCTTCTTCTCCCCAGTCG
3' ss Score
10.32
Exon sequences
Seq C1 exon
GGGCAGAGGAAGGAGCTCTCGGGGCCAGAGGGAAAGCAGAGCCGGCCCTGCATGGAGGAAAATGAATTGTACAGCAGCGCAGTCACAG
Seq A exon
GTGAGGGGGCGGGGGCTGCCCTGCTCTCCCCTGGGGGCTCTCCCCAGGGTGAGGTGGAGAGGAGGTGTGGGCTGGCTAGCTGCTGGCCCCGAGTCTTCCTGCCTTGTGGTTATCCCCAGCCTGGGCCAGCCCCGTTATCAGCCTCTCCTTCTCGCTTCCGGGTGCAGCCCAACGTAGGGAGCCTACCCTGCCTTGAGTCTCTCCCTTGGTTCACCTCATCTTACCTAGGGCCTGCTGGTGGGAGAGGGGAAGGCTGGGGGCCCAGGTGAGGGTGCTGCTTTTTTCTATTTTTGAGACGGAGTTTTGCTCTTGTCGCTCAGGCTGGAGTGCAATGGCACAATCTCGGCTCACTGCAACCGCCGCTTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGCAGCTGGGATTACAGGCGTCGGCCACCACGCCTGGCTAATTTTTTGTATTTTTAGTAGAGTCGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACATCAGGTGATCCACCTGCCTCAGCCTCCCAAAGTGTTGGGATTACAGGCATGAGCCACTGCGCCTGGCCCCAGGTGTTGCTTTTGAGGAGCTGGTGGAGGGAGGAGAAACTTTCATCTGCCTTCCATCTAAGCTTCACCCCCAGGGCCCCGGCAGTGGGAGGGCAGGGCCAAGGCTTCACCTGCAGCTGTGACCGTAGGGACTAGGGTGGTGGCTGGTTTGGGGTGAGAGATGGGGTGGGGAAGACAAGACTGTGGCTCTGGCGACAGGGGCAGGAAGGATGTGGGCACGAGGTTGGGGTGGATGTGGGTAGGGGCGTGATGCCTACTAGGGTAGGGGGTGGAGGTACCTGGCCTTTTGGGGAGTATGACCTGGCACAGAGCAGCTCAGCCTCCAAGACCCAGGCAGGGGGCCATAAGTGTGTGGATAATACTTTCTAGAAAAGTTCTGGTACGCTCATTTAGAACTGGGCAGTGGTGAGGCAGGCCAGCTGTTTCCCATTAACTGCCTTCGCCTTCTCTCTCTTCTTCTCCCCAG
Seq C2 exon
TCGGCCCCCACAAGGAATTTGCTGTGACCATGAGACCTACAGAAGCCAGTGAGAGGTGCCACCTGCGGGGGTCCTATACCCTCCGGGCTGGGGAGAGTGCCCTGGAGCTGTGGGGTGGGCCCGAGCCAGGGACCCAGCTGTACGACTGGCCCTACAGGTTTCTGCGGCGCTTTGGGCGGGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000147443-DOK2:NM_003974:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.450 A=NA C2=0.130
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0217412=IRS=PU(58.4=95.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGCAGAGGAAGGAGCTCTC
R:
CAAAGCGCCGCAGAAACCT
Band lengths:
262-1305
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)