HsaINT0051458 @ hg38
Intron Retention
Gene
ENSG00000147443 | DOK2
Description
docking protein 2 [Source:HGNC Symbol;Acc:HGNC:2991]
Coordinates
chr8:21910673-21911988:-
Coord C1 exon
chr8:21911901-21911988
Coord A exon
chr8:21910858-21911900
Coord C2 exon
chr8:21910673-21910857
Length
1043 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
CTCTCTCTTCTTCTCCCCAGTCG
3' ss Score
10.32
Exon sequences
Seq C1 exon
GGGCAGAGGAAGGAGCTCTCGGGGCCAGAGGGAAAGCAGAGCCGGCCCTGCATGGAGGAAAATGAATTGTACAGCAGCGCAGTCACAG
Seq A exon
GTGAGGGGGCGGGGGCTGCCCTGCTCTCCCCTGGGGGCTCTCCCCAGGGTGAGGTGGAGAGGAGGTGTGGGCTGGCTAGCTGCTGGCCCCGAGTCTTCCTGCCTTGTGGTTATCCCCAGCCTGGGCCAGCCCCGTTATCAGCCTCTCCTTCTCGCTTCCGGGTGCAGCCCAACGTAGGGAGCCTACCCTGCCTTGAGTCTCTCCCTTGGTTCACCTCATCTTACCTAGGGCCTGCTGGTGGGAGAGGGGAAGGCTGGGGGCCCAGGTGAGGGTGCTGCTTTTTTCTATTTTTGAGACGGAGTTTTGCTCTTGTCGCTCAGGCTGGAGTGCAATGGCACAATCTCGGCTCACTGCAACCGCCGCTTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGCAGCTGGGATTACAGGCGTCGGCCACCACGCCTGGCTAATTTTTTGTATTTTTAGTAGAGTCGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACATCAGGTGATCCACCTGCCTCAGCCTCCCAAAGTGTTGGGATTACAGGCATGAGCCACTGCGCCTGGCCCCAGGTGTTGCTTTTGAGGAGCTGGTGGAGGGAGGAGAAACTTTCATCTGCCTTCCATCTAAGCTTCACCCCCAGGGCCCCGGCAGTGGGAGGGCAGGGCCAAGGCTTCACCTGCAGCTGTGACCGTAGGGACTAGGGTGGTGGCTGGTTTGGGGTGAGAGATGGGGTGGGGAAGACAAGACTGTGGCTCTGGCGACAGGGGCAGGAAGGATGTGGGCACGAGGTTGGGGTGGATGTGGGTAGGGGCGTGATGCCTACTAGGGTAGGGGGTGGAGGTACCTGGCCTTTTGGGGAGTATGACCTGGCACAGAGCAGCTCAGCCTCCAAGACCCAGGCAGGGGGCCATAAGTGTGTGGATAATACTTTCTAGAAAAGTTCTGGTACGCTCATTTAGAACTGGGCAGTGGTGAGGCAGGCCAGCTGTTTCCCATTAACTGCCTTCGCCTTCTCTCTCTTCTTCTCCCCAG
Seq C2 exon
TCGGCCCCCACAAGGAATTTGCTGTGACCATGAGACCTACAGAAGCCAGTGAGAGGTGCCACCTGCGGGGGTCCTATACCCTCCGGGCTGGGGAGAGTGCCCTGGAGCTGTGGGGTGGGCCCGAGCCAGGGACCCAGCTGTACGACTGGCCCTACAGGTTTCTGCGGCGCTTTGGGCGGGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000147443:ENST00000276420:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.450 A=NA C2=0.161
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0217412=IRS=PU(58.4=95.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGCAGAGGAAGGAGCTCTC
R:
CAAAGCGCCGCAGAAACCT
Band lengths:
262-1305
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development