HsaINT0051465 @ hg19
Intron Retention
Gene
ENSG00000146094 | DOK3
Description
docking protein 3 [Source:HGNC Symbol;Acc:24583]
Coordinates
chr5:176931744-176932111:-
Coord C1 exon
chr5:176932012-176932111
Coord A exon
chr5:176931917-176932011
Coord C2 exon
chr5:176931744-176931916
Length
95 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGT
5' ss Score
11
3' ss Seq
GTCCTGGCCACCTGCCACAGTGG
3' ss Score
2.58
Exon sequences
Seq C1 exon
GGGACAGGGGAGGCCTCCTCAGGATCCACAGATGCCCAGTCTCCCAAGAGGGGCCTGGTCCCCATGGAGGAAAACTCCATCTACTCCTCCTGGCAGGAAG
Seq A exon
GTAAGTTGGAGGACGTGCAAGGGCAGCCTCAGCCCCCCACACCCAGGGCTGGGTCTTTTTGGGACTGACGGAGCTGTCCTGGCCACCTGCCACAG
Seq C2 exon
TGGGCGAGTTTCCCGTGGTGGTGCAGAGGACTGAGGCCGCCACCCGCTGCCAGCTGAAGGGGCCGGCCCTGCTGGTGCTGGGCCCAGACGCCATCCAGCTGAGGGAGGCCAAGGGCACCCAGGCCCTCTACAGCTGGCCCTACCACTTCCTGCGCAAGTTCGGCTCCGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000146094-DOK3:NM_024872:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.520 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0217412=IRS=PU(1.6=2.9)
A:
NA
C2:
PF0217412=IRS=FE(90.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCATCTACTCCTCCTGGCAGG
R:
TGGTAGGGCCAGCTGTAGAG
Band lengths:
169-264
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)