HsaINT0058508 @ hg19
Intron Retention
Gene
ENSG00000167880 | EVPL
Description
envoplakin [Source:HGNC Symbol;Acc:3503]
Coordinates
chr17:74002927-74007749:-
Coord C1 exon
chr17:74007657-74007749
Coord A exon
chr17:74006625-74007656
Coord C2 exon
chr17:74002927-74006624
Length
1032 bp
Sequences
Splice sites
5' ss Seq
AAGGTACAC
5' ss Score
7.56
3' ss Seq
ACCCTTCTTCCTCTCTGCAGAAG
3' ss Score
11.81
Exon sequences
Seq C1 exon
GAGAAGAACCTTGCAAAGGCCTATACTGAGGTTGCAGCAGCACAGCAGCAGCTGCTCCAGCAGCTGGAGTTTGCTAGAAAAATGCTGGAGAAG
Seq A exon
GTACACAGACAACACCTACAGCTTTCCCACAATAGCCAGGAATAACCAGGAATGCCCACTCCATTCCCAAAATGCCAGGCTGTCACCCTGGTAGTCTCCTTCCCTCCTCTCCCTCCTGCCTGCAGCCCCTGGGCAGCTCTGGCTGCTGGAGAGGGGAGCGGATTCCAGCCACCCAGTTTTCTCTCCAGCAGCTCTTACAGGCTGGTGTCCATCCCAGGGTTAGGCCCTGGAGATGGCATTCATGGCCACTGGGCATCCTCCAATGGGACAAGACCTCTAACCCCAGAGAGCAGAGAAAATCCCCTAGAGCTTCACCCTCAGCCACCTGGCTCTCCACCTTCGGCCTACACACCCTCAAGCCAGAACTTCTCCAGGACTCCTGGTGACTTGCCAGCTTTTCTGTTACCCTCGGCCACAGTCAGGGTCCCTGGATGGAAGGGGAAAAGGGAGAGGTTCTGGAGGGACAGGGAGAACCTGTCCTGTTTGCACTTTTTTTTTGTTTTTTGTTTTTTTTGAGACGGAGTCTCGCTCTATCACCAAGGCTGGAGTGCAGTGGCACAATCTCAGCTCACTGCAACCTCCGCCTCCCTGGTTCAAGCGATTCTCCTGCCTCGGCCTCCTGAGTAACTGGGATTACAGGCATGCGTCACCACGCCCAGCTAATTTTTTGGATTTTTAGTAGAGATGGGGTTTCACTATGTTGATCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCGCCCACCTTGGCCTCCCAAAGTGTTGGGATTAAAGGCATCAGCCATTGCACCTGGCCCTTACTTGCACTTTCTAATGCAAACCAGGCCTGCGCACTGCCTTGGGTCCTAAAATCATTGCATTGACTGGGTCTTCTCAAAATCCTATATCCAAGCATCTTAGGTCTTCAGCTCCACCTCTGAGGACCCACTGGGGAGTCTCAGGAAACAGGGAGGGGTCTTTCATCTCAGGAAAAACATGGAGCTCCTATCTCTACCGCCCACCCCGTGCTCTACCCTTCTTCCTCTCTGCAG
Seq C2 exon
AAGGAGCTCAGTGAGGACATCCGAAGGACCCATGATGCAAAGCAGGGCTCCGAGAGCCCTGCCCAAGCAGGGAGAGAGTCAGAGGCCCTGAAGGCCCAGCTGGAAGAGGAGAGGAAGCGGGTGGCCCGGGTGCAGCATGAGCTGGAGGCGCAGAGGAGCCAACTGCTGCAGCTGAGGACCCAGCGGCCCTTGGAGAGGCTGGAGGAGAAGGAAGTGGTAGAGTTCTACCGGGACCCCCAGCTGGAGGGCAGCCTGTCCAGGGTGAAGGCCCAGGTGGAGGAGGAGGGCAAGCGGCGGGCTGGCCTGCAGGCAGACCTGGAAGTGGCAGCCCAGAAGGTCGTGCAGCTGGAAAGCAAGAGGAAGACCATGCAGCCTCATCTGCTGACCAAGGAGGTCACCCAGGTGGAGAGGGACCCCGGCCTGGACAGCCAGGCGGCCCAGCTCAGGATCCAGATCCAGCAGCTCCGCGGGGAGGATGCCGTCATCTCGGCCCGGCTGGAAGGGCTGAAGAAGGAGCTACTGGCCCTTGAGAAGAGGGAGGTGGACGTGAAGGAGAAGGTCGTGGTGAAAGAGGTAGTCAAGGTGGAGAAGAATCTGGAAATGGTCAAGGCAGCCCAGGCTCTGAGGCTGCAGATGGAGGAGGATGCTGCGCGGAGGAAGCAGGCGGAGGAGGCTGTGGCCAAGCTACAGGCTCGCATCGAAGACCTGGAGCGGGCTATCAGCTCGGTGGAGCCCAAGGTCATCGTGAAGGAGGTGAAGAAGGTGGAGCAGGACCCAGGGCTCCTCCAGGAGTCCTCCAGGCTGAGGAGCCTCCTCGAGGAGGAGAGGACCAAGAACGCGACGCTGGCCAGGGAGCTGAGCGACCTGCACAGCAAGTACAGCGTGGTGGAGAAGCAGAGGCCCAAAGTGCAGCTCCAGGAGCGCGTCCACGAGATCTTCCAGGTGGATCCGGAGACAGAGCAGGAGATCACTCGGCTCAAGGCCAAGCTGCAGGAGATGGCGGGCAAGAGGAGCGGTGTGGAGAAGGAGGTGGAGAAGCTGCTGCCCGACCTGGAGGTCCTGCGGGCCCAGAAGCCCACGGTGGAGTACAAGGAGGTGACCCAGGAGGTGGTGAGGCATGAGAGGAGCCCCGAGGTGCTGCGTGAGATCGACCGCCTGAAGGCTCAGCTCAACGAGCTCGTCAACAGCCACGGGCGCTCCCAGGAGCAGCTCATCCGCCTGCAGGGTGAGCGCGACGAGTGGAGGCGCGAGCGGGCCAAGGTGGAGACCAAGACGGTGAGCAAGGAGGTGGTGCGCCACGAGAAGGACCCGGTGCTGGAGAAAGAAGCAGAGCGGCTCCGCCAGGAGGTGCGGGAGGCGGCCCAGAAGAGGCGGGCCGCGGAGGACGCGGTGTACGAGCTGCAGAGCAAGCGCCTGCTGCTGGAGAGGAGGAAGCCCGAGGAGAAGGTGGTGGTGCAGGAGGTGGTGGTCACCCAGAAGGACCCGAAGCTGCGCGAGGAGCACAGCCGGCTGAGCGGGAGCCTGGATGAGGAGGTGGGCCGGCGGCGCCAGCTAGAGCTTGAGGTGCAGCAGCTGCGGGCCGGCGTGGAGGAGCAGGAGGGCCTGCTCAGCTTCCAGGAGGACCGCAGCAAGAAGCTGGCCGTGGAGAGGGAGCTGCGGCAGCTGACCTTGAGGATCCAGGAGCTCGAGAAGCGGCCTCCCACGGTGCAGGAGAAGATCATCATGGAGGAAGTGGTCAAGCTGGAGAAGGACCCGGACCTGGAGAAGTCCACGGAAGCCCTGCGGTGGGACCTGGACCAGGAGAAGACCCAGGTAACCGAGCTGAATCGGGAGTGCAAGAACCTGCAGGTCCAGATTGACGTCCTCCAGAAAGCCAAATCGCAGGAGAAGACCATCTACAAGGAAGTGATCCGGGTGCAGAAGGACCGCGTCCTGGAAGATGAGCGGGCCCGCGTGTGGGAGATGCTCAACAGGGAGCGCACGGCCCGGCAGGCCCGGGAGGAGGAGGCACGGCGCCTGCGGGAGCGCATTGACCGGGCCGAGACGCTGGGGAGAACCTGGTCCCGGGAGGAGTCCGAGCTGCAGAGGGCCCGGGACCAGGCCGACCAGGAGTGTGGGCGGCTGCAGCAGGAGCTGCGGGCTCTGGAGAGGCAGAAGCAGCAGCAGACACTGCAGCTGCAGGAGGAGTCGAAGCTGCTCAGCCAGAAGACGGAGAGCGAGCGACAGAAGGCGGCCCAGCGGGGCCAGGAGCTCTCGCGGCTGGAGGCGGCCATCCTCCGCGAGAAGGACCAGATCTACGAGAAGGAGCGGACGCTCCGGGACCTCCACGCCAAGGTGAGCCGGGAGGAGCTCAGCCAGGAGACCCAGACGCGAGAGACCAACCTTTCCACCAAGATCTCCATCCTGGAACCCGAGACGGGGAAGGACATGTCCCCATACGAGGCCTACAAGAGGGGCATCATCGACAGGGGCCAGTACTTGCAGCTGCAGGAGCTCGAGTGTGACTGGGAGGAGGTCACCACCTCGGGGCCCTGTGGGGAGGAGTCTGTGCTCCTGGACCGCAAGAGCGGGAAGCAGTACTCCATCGAGGCCGCCCTCCGCTGCCGGCGCATCTCTAAGGAGGAGTACCATCTGTACAAGGACGGCCACCTGCCCATCTCCGAGTTTGCGCTGCTTGTAGCTGGGGAGACCAAGCCAAGCTCCTCACTCTCCATCGGCTCTATCATCTCCAAGTCCCCGCTCGCCTCCCCGGCCCCCCAGAGCACCAGTTTCTTCTCTCCCAGCTTCTCTCTCGGGCTCGGTGATGACAGCTTCCCTATCGCCGGGATCTATGACACAACCACAGACAACAAGTGCAGCATCAAGACGGCCGTGGCCAAGAACATGCTGGACCCCATCACTGGGCAGAAGCTACTGGAGGCCCAGGCGGCCACAGGGGGCATCGTGGACCTGCTCAGCCGTGAGCGCTACTCTGTGCACAAGGCGATGGAGAGGGGCCTGATCGAGAACACCTCCACACAGAGGCTGCTTAACGCCCAGAAGGCCTTCACCGGCATCGAGGACCCCGTCACCAAGAAGAGGCTCTCGGTGGGCGAGGCCGTCCAGAAGGGCTGGATGCCCCGGGAGAGCGTGCTCCCACACCTGCAGGTGCAGCACCTGACCGGGGGGCTCATCGACCCCAAGAGGACAGGCCGCATCCCCATCCAGCAGGCCCTCCTCTCCGGGATGATCAGTGAAGAGCTGGCCCAGCTCCTGCAGGACGAGTCCAGCTACGAGAAGGATTTGACAGACCCCATCTCCAAGGAACGGCTGAGCTACAAGGAGGCCATGGGCCGCTGCCGCAAAGACCCCCTGAGCGGCCTGCTGCTCCTGCCAGCGGCACTGGAGGGGTACCGCTGCTACCGCTCCGCCTCCCCCACCGTCCCGCGCTCCCTTCGCTGACACGGGCCAAGGAGCCAGTGGGGAAGTGCGTGTGTTGGGCCAGGTAGGATACGTACACCTCTTGCCTCAGAGCAGCCTCATCCCAGGCAGTGGGTCTTCCCTCTGTCCAACCACTGTTTTATTATTTTACTAACATGGTGATGGGCTCCCTCCCCTAACCTTGGTGCCTGATCCATCCCCAGACCAGGACAGCAGCCACTCAGTTCTTCCTCCACCTCCACCCAGTGATCCCAATAAACGAATTCTGTCTCCCCGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000167880-EVPL:NM_001988:21
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.223
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0068115=Plectin=WD(100=3.7),PF0068115=Plectin=WD(100=3.1),PF0068115=Plectin=WD(100=3.9),PF0068115=Plectin=WD(100=3.4),PF0068115=Plectin=WD(100=3.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCCTATACTGAGGTTGCAGC
R:
CTCCTCCACCTGGGCCTTC
Band lengths:
358-1390
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)