HsaINT0064382 @ hg38
Intron Retention
Gene
ENSG00000105701 | FKBP8
Description
FK506 binding protein 8 [Source:HGNC Symbol;Acc:HGNC:3724]
Coordinates
chr19:18537601-18538436:-
Coord C1 exon
chr19:18538216-18538436
Coord A exon
chr19:18537774-18538215
Coord C2 exon
chr19:18537601-18537773
Length
442 bp
Sequences
Splice sites
5' ss Seq
AAGGTGACC
5' ss Score
6.78
3' ss Seq
CGGGCACTGTCTCCCAATAGTGG
3' ss Score
6.71
Exon sequences
Seq C1 exon
CAGGAGCCCATACATCCCCCCGCACGCGGCCCTGTGCCTGGAGGTGACCCTGAAGACGGCTGTGGACGGGCCTGACCTGGAGATGCTCACGGGGCAGGAGCGCGTGGCCCTGGCCAACCGGAAGCGGGAGTGCGGCAACGCCCACTACCAGCGGGCGGACTTCGTCCTGGCCGCCAACTCCTACGACCTCGCCATCAAGGCTATCACCTCCAGCGCCAAAG
Seq A exon
GTGACCGCCTGGGTCAGATCTCCACCATCTCCCCTGCAAAGGTGTCCACTCCGTGCCAGAAACTTCCAGCCCCAGAGAGCCTCAGACTCAGAATATTCTAGAATAGCCCAGAATATGGGTAGATCCCCAACTGCCCCTAAGCTAGGGCCTGTTACAGACTCGTGGTATATCCCAGACCAGTGGAGTGTTGTAGAATGCAAGTGGATATGGGGATGGGGTGACCATAGACAGGGCCAGTTCACATGTACCACAGGCTAGGCCCTCGCTTGCTTAAGTCTCCATCTTGTAGCTTCCTCAGGAGAGCCCCAGGAAAGCGTGGCCCTTGGTCCGGGGTTAAAATTGGGGAAACTGAGGCCAGAGAGGCAGCCTCCGCAGAGGGGTGGGTGCCGGGGTGTCTGGTGGCATGGTGACGGCTGCCGTGGCGGGCACTGTCTCCCAATAG
Seq C2 exon
TGGACATGACGTTCGAGGAGGAGGCACAGCTCCTGCAGTTGAAGGTGAAGTGTCTGAACAACCTGGCGGCCTCGCAGCTGAAGCTCGACCACTACCGCGCAGCCCTGCGCTCCTGCAGCCTTGTGCTGGAGCACCAGCCAGACAACATCAAGGCTCTCTTCCGCAAGGGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105701:ENST00000597960:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.012 A=NA C2=0.002
Domain overlap (PFAM):
C1:
PF0025423=FKBP_C=PD(19.1=23.0)
A:
NA
C2:
PF134321=TPR_16=PU(58.5=65.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTGGAGGTGACCCTGAAGAC
R:
GCGGAAGAGAGCCTTGATGTT
Band lengths:
349-791
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development