HsaINT0065098 @ hg19
Intron Retention
Gene
ENSG00000184922 | FMNL1
Description
formin-like 1 [Source:HGNC Symbol;Acc:1212]
Coordinates
chr17:43316322-43317992:+
Coord C1 exon
chr17:43316322-43316432
Coord A exon
chr17:43316433-43317842
Coord C2 exon
chr17:43317843-43317992
Length
1410 bp
Sequences
Splice sites
5' ss Seq
GAGGTAAGC
5' ss Score
9.85
3' ss Seq
TCCTTCCATCTGGGGGACAGAGG
3' ss Score
1.64
Exon sequences
Seq C1 exon
GTGGCCTGCATGCAGTTCATCAACATTGTGGTACATTCGGTGGAGAACATGAACTTCCGTGTCTTCCTGCAATATGAGTTCACCCACTTGGGCCTGGACCTGTACTTGGAG
Seq A exon
GTAAGCCCTGTACTGCCCCCCAGACTGAACTGCCTGCCCACGGCAGAGTATGGCTGAGTGGTTAGCAGCATGAGTGCTGGGGTCAGGTAGACCTGGGTTTAAATCCTGGCTCTGCCGTTGCCTGCCGTGTGACCTTGGATAGGCCTCTTCCTCTCTCTCAGTGTCAGTTTTGCCATCTGTGAAATAGGAGAATCATAGAAGATAATCTTGACTCTAAATGCATAGACCAGTGCCTGGCACATACCAGGCCCCCAGTCTATGGAACTGTTTTTGCAGGCACCAGAACAGGTCAAGGTAGCCCAGAGTCTGGCTCTGGGAGCACCAGCCTCAGACAGGTGCTCTGACTCCAGCATATAATGGGGAACCCAGAGATACAGGGTAGAAGCAGGAGTTGGCTCATGCTGGATGGGCCCAGGACATGGAGGAGTTCCCTGCCCTGGGGAAGGTGGGCAGAGCTGCTTGGTGCTTCCTGGCCCAGGCTGAGCAGAGAAGCTGCAGCTCCTTCTCTGCTTCCTTTGGGAGGTTTCCTGGAGGAGCGGGGCTTTCGGGGTTGGATTTTTGAAAGCCAGGATTAACAAAAGGTAGAGAGCAGGCTGGCGGGGGGGTCTATCTGTGCAATGGAGTATTATTCAGCCACAAGAAGGAATGAAGTATTGACACATGGTACAACATGGGTGAGCCTTGAAAACATGCTAAGTGAAAGAAGCCAGACACAAAAGGTCACGTACTCTATGATTGCTTTTTTTTTGAGATGGAGTCTTGCTCTGTTGCCCAGGCTAGAGTGCAGTGACACGATCTTGGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGTGATTTTCCAGCCTCCCCAGTAGTTGGGATTATAGGTGCCCACCACCACACTCGGTTAATTTTTGTATTTTTGGTAGAGACGGGGGTTTCACCACGTTGGCCAGGTTGGTCTTGAACTCCTGACCTTAGGTGATCCGTCTGCCTCAGCCTCCCACAGTGCTGGGATTACAGGCATGAGCCACCTCGCCCAGCTATCTATGATTGCTTTATATGAAATGTCCAGAATGGGTAAATCCATAAAGATGGAAAGTAGATTAGTGGTTGCCAGGGACTGGGGGAGGAGAGAATGGCAAGTGACTGCTGACGCCTGTGGGGTTTCTTTTTGGGCTGATGACAATGTTCTGGAATTAGATAATGGTGATGGTTGCACAACCTTGTGGCTATACTAAGAATGACTGAATTGTACACTTTAAAATGGATTTTATGATTTGTGAATTATATATTAAAAAATAAAGAAAAAGTAGGCTAGGGCTCAGGCCCCTTCCTCTGGATGGCAGTGGTGGCAGGGGGGTGGTTTGGAAAGACTCCCCCCCACACACACACCAGGCCTCACCCCACTCCTTCCATCTGGGGGACAG
Seq C2 exon
AGGCTTCGGCTCACCGAGAGTGACAAGCTGCAGGTGCAGATCCAGGCGTACCTGGACAATATTTTTGATGTGGGGGCGCTGCTGGAGGACACAGAGACCAAGAACGCTGTGCTGGAGCACATGGAGGAACTGCAGGAGCAAGTGGCGCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000184922-FMNL1:NM_005892:11
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.060
Domain overlap (PFAM):
C1:
PF0636711=Drf_FH3=FE(21.3=100),PF138701=DUF4201=PU(5.1=13.5)
A:
NA
C2:
PF0636711=Drf_FH3=FE(29.0=100),PF138701=DUF4201=FE(50.0=100),PF029949=Transposase_22=PU(37.3=56.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCTGCATGCAGTTCATCAAC
R:
CAGCGCCACTTGCTCCTG
Band lengths:
258-1668
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)