HsaINT0065099 @ hg19
Intron Retention
Gene
ENSG00000184922 | FMNL1
Description
formin-like 1 [Source:HGNC Symbol;Acc:1212]
Coordinates
chr17:43317843-43318597:+
Coord C1 exon
chr17:43317843-43317992
Coord A exon
chr17:43317993-43318495
Coord C2 exon
chr17:43318496-43318597
Length
503 bp
Sequences
Splice sites
5' ss Seq
CTGGTGAGA
5' ss Score
7.54
3' ss Seq
ACCATGTGCTGGTGCTACAGCTG
3' ss Score
5.54
Exon sequences
Seq C1 exon
AGGCTTCGGCTCACCGAGAGTGACAAGCTGCAGGTGCAGATCCAGGCGTACCTGGACAATATTTTTGATGTGGGGGCGCTGCTGGAGGACACAGAGACCAAGAACGCTGTGCTGGAGCACATGGAGGAACTGCAGGAGCAAGTGGCGCTG
Seq A exon
GTGAGAGTGGGTCCTGACCCCAGCCCAGCACATCATAGGCCCACAGGGCACACGGGCCACAGGGCCACGCAAGCATGGGCACTGGGCAGCAGACAGTGTTATAATTGTGCATTGGAGGTGCTGCCTGCCTGGCCCCAGAGCCTGGCCTGAATCCAAAGCCTGAATCTGTTGGGTGTCTTTCTCAATGAGTGTGGGTGAGCACCCTCACTGACAGGCCCCTCCTCTACCCAGGCTCAGACCCCAGGTGAACTGAAATGGGTGCCTGGGGCCCCTCCCAGCTCAGTCTCCTCCTCTCCCTCCACCTCCCGCATCACTGGTACCTTGGTTTCCTCTCCTTATTTGCTTGGGTTCGAGTGCCAGGCTCGGCCCACCCTTGGCACCTGGGCTGAGCGGATCTGGGAGCCTCCCCCAGTCTTCCAGGCAGGCATGCCTGATGCCGCCCCCTCACCGGCGGTGCCAGTGCCGGGCTGCGGGTCGGGGCTCACCATGTGCTGGTGCTACAG
Seq C2 exon
CTGACAGAGCGGCTTCGGGACGCGGAGAACGAATCCATGGCCAAGATTGCAGAACTGGAAAAACAGCTAAGCCAGGCGCGCAAGGAGTTGGAGACCCTGCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000184922-FMNL1:NM_005892:12
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.060 A=NA C2=0.353
Domain overlap (PFAM):
C1:
PF0636711=Drf_FH3=FE(29.0=100),PF138701=DUF4201=FE(50.0=100),PF029949=Transposase_22=PU(37.3=56.0)
A:
NA
C2:
PF0636711=Drf_FH3=FE(19.5=100),PF138701=DUF4201=FE(33.7=100),PF029949=Transposase_22=FE(44.0=100)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCGAGAGTGACAAGCTGCAG
R:
CGCAGGGTCTCCAACTCCTT
Band lengths:
238-741
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)