HsaINT0065128 @ hg19
Intron Retention
Gene
ENSG00000157827 | FMNL2
Description
formin-like 2 [Source:HGNC Symbol;Acc:18267]
Coordinates
chr2:153476023-153482076:+
Coord C1 exon
chr2:153476023-153476232
Coord A exon
chr2:153476233-153481951
Coord C2 exon
chr2:153481952-153482076
Length
5719 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGA
5' ss Score
10.77
3' ss Seq
ATTCTCTTTGATGTCTTTAGCTG
3' ss Score
7.05
Exon sequences
Seq C1 exon
TGCAAAATGGTCCAGTAACACCACCTATGCCACCGCCGCCGCCGCCCCCTCCTCCACCTCCTCCTCCCCCACCGCCCCCTCCGCCTCCTCCTCTCCCAGGCCCTGCAGCTGAGACTGTACCAGCTCCTCCCTTAGCACCTCCCCTTCCCTCTGCACCTCCGCTGCCTGGAACATCTTCACCCACAGTGGTTTTCAACTCAGGATTAGCAG
Seq A exon
GTAAGAGCACAGAATTCAAACCCAGGTACTCATATCAGAAATGCTGTCTTATCTCGGAGAGTTGAAGCTATTCTTTCAAAGTCCAGGTCTCTTGCAATGATGTGTATCTCTTCCTAGTATAAGAAATTCCTGCTGATGTAGCCGATAGAGGGAACATCATCACGCATGGGAGGCACTTTGCTCTGAGTAGTCTTTGTCACAACCACACCCCACAATGGGAGGTTCTGATCTCCTACACCATCTTCCTGCCTTCCACTGGCCCCACCGAGAGAATGGAAGAGAGACAAGCTACCTGCTTGAGGATCAGTGCATTTTTGTGGGTTCAGCAGATACTTTCTGGACACCTGTAGTATTCAAAGCTCAGTATTAGGCACAGACATTGAGTGCTTCTGGATCTTTTTTTTTTTAAATGGTATTTTTGATGTCATCTATAAAAGGGAAACATGCTTTTATGTGTAATTGCCTGACGTAGGCTTCCAGGCATGTCTTCTGAGCATTCGAGAACATCAGAATTTGCTAGAGTGGATTTAAACTTCAAGGAGGAAGTGCTGCCAACAGCCGTATTATCATGCCTTAAAATGCTGCCAAATAATTCATGTCCTCTTGCCAACCAGAAGATAGAAAACAGCATCCTCACCTCACCAGAAATAAAATGGGAGGTAGGGGTTAGAGCAGGAGGAAGAGTCACTCTAATGCCTTGAAATCTAAGCTCTTTGTTTTGACTCACGGAAACAAAGATGACGCTACGAGCCGTTTTCTCAGTCCTGAAGTGTTTCCCTGGCATCTGGAATTGCTCTAAGCTTTGCCATCCCTGTGACGTGGGGTAATTCTGCCTCCTCATTTACTTCAGCCTGTTCATGAGGTCTCTTATTTACAATAAAGAACTACCACTCTAATAGCCTCCATTTCCAAGGCTGTGATAGTTCTCAGAGCCTTTTGCCCAAAGTCTAAAAGCCAGTCTTAGCTGTAAAGATTTCCCAATCTCCATCCCTTCCAGGATCCCATCTGCAGCTCTGCCAGCCGGTCACTGGGGCTCATTCATCCCAATGACTGGAGCCCTTTTGGATGCCCCAGAGTCACCTAGAATAAATTCACTCCACATCAAATCCATGGTTTTACTTCCACCCCGACTTCTATATAAAACTGTCAGGGAAACAAGATTCCAGTTCACAGTAAGGTCCACAGTAAATCGGTGACTTATTTCTACCCTTCAAGATCTTCCCCGTCTACCACTTTCTTCTAGAACTTTTATTACTTCTGAAGGAGAAAAGTTGGAGCAGAGTCATCGTGGAACTGATGGACTATGGAATATAAACAGACAAACAAGAAACCTCATATCAAGCCCCGGGAATGTGTTCCATCACCAGGCTGTTGTCAGTAACTGGGTGTGGAAACCCATTATCGTCCCGTGCACCTGGCCACCCTGATTAGGCACTCTTGGTAGCCCCCAAGGCGCACTTGCTGTGAGATGTGTCTGCTGTGGTATCTCATTTGGGGCTGCTTCCTTTGTCTCTGACAAACGCTGATGTGTGATTTAGCACCCACTTCCACGCACCTGAGCACTAACATAGACCTCAGAACCGCCTTAGCCGAGTGAGAGCCCAGAGGCTGAGATGTGTCTAGAGCTTCCTTCCAAGGGGCCATGTCCTGTGTGATTGATCTATTTATTAATTGTTTTGCTTGGGTTCTTCCCACTACTTGATTTTAAAAATGTGTTGGCTCTGTCAATTGCCTCAATATTTTAAGGTGTAGAGCTCTGTGCTTGGCTGATAACCAACTGCTTTTAGGGTTTGCTATACTTGGAAGTGGTCCCTGTTGTGGCTCATGCAATTTAGAGGACTGTAGGTGGGAATACAGGAACTCTTTATTTCCATAAGTGTCCACTAAATGATTGTGAGGGATGTCTTGGAAGCATTATAAGATCCTTGTGAGTCTTTGATAGCTCGAGATCAGGCAATTTCTCCAAGGCCTTTAATCTTTCTTTATTATTCATCCTTATTTAGACTGTTAATTCTTAGTGATTGAAGCCCATTTGGTGAGATGTTTTGCTAGTGTGTTGAGTAACTCTCTCTCTCACTCTGGAACCAAGAGGCCAGACAGAATCAGGATGCCCAGTAGAATGAAGAGACAGAGCTGAGCTAATATTCTGAAGCCTCCTGGGAAGTCAGAAACCTATGACATCACTTGGCCTCTGGACCCACAGGCAACACGAGGGTCTTATCTCTTCAATGGGCAGGTGTGTTCTTGGAGACCAAGACAGAAGACCAAGAGGAGAGCCCCATAGTTTATCTAGTTGAGAGTTTTCTTTGTATTTTATAGAGAAAATAGTAGTAGTGTGAAATATGCATTTGAAGAAGAAGGCTTCCTTCCTCTCAAGTCTGTGATAGAACAACCTGGCTCCCTTTCCCCCGGTAGGTCACCTGAGACAGGCTGCTGAGCAGGTGGAACCTTTGCCGTCTGTCTGGGAGGATGTGCTCGGATCCTCACAATGCGAATTTGGACTTTGGTTGATTGTTTTTCATGTAAAAATTATTCCTATCCTATGGAATGCCTAGCACAGTTCAGTATTGCTGTTTGGTACCACTACGATGAAATAATTTTTTTCTTCCCTCTTCTAAAAAGGATAATTTTAAAAATGAAATAGTTGAGTCTTGGAGGCAGGCCTGAATGGAAATGAATTTTTGGCTCTGTGCCGCCTTGTGAAATGTGTCCAAGAAGCATGAAATTCTATGCTGAGTGCGTGAACTGCTGAGCCACTTGACTCTAACCATATCTAATTTTTTTTGTATTTTCTCTGTTCTTTCTGCTTCCACAAAAGATGGGCCAATCAAGCTTTTCTGTAGGTTGCTCCTCACTGAGTGTGTTGAGTATTTGCCATGTGTTTCTGTTGGTCACACTGTGCCTTGACATCTTTCCACTCCATTTTGCTTTGATCCATTGCATTTTGACTTTGTGTCTGCGGGAAGTCTTGGTGGTGGCTGATGATGATTCCAGGTTTGCCCACACATTCTAGTTGAACCTACATAAGAGACTATTGTCCTTGAAGCAGACATCCTGGATTCATATGCCCTCTTCCATTTCCTCTGAGAAAAGGTTTTTTTTTTTTTTTCTTCTTCTTCTTTTAATTTTTATATTTGTATCTGAGACTTCAACTCTAAGAACAAAAAAAAGGTGCCAGGTGCCCCTTTTCCATTCCCTCCCTCATGCTGGTCTCTGGCCCACTCCAGGGAGCACTCACCCGCCTTTAGCCCGAGCCATGGGGACACAGTGTGTCCAGTGGTCACCTATGTGCTTTCCTCCTCTTCCCACTCCCACCCTGGTTAAAGCCAGGAAAACCTTTCCAAGGAGGAGAACTTTCTTGCCTGTGTTCTGATCTCAGGCTTATTCCTGACCTTGCTAAATAGTTAGAAGGGTGGTTGCAAATGGCAAACTTCTAGCGAGCGTCATGAGCCTACCATGTCTGTGGGAGGAAGGTAGGACGCCATTGGCACCAACCTGTCACCTCAGGTTATGAAAAGACTCCTCTGCGGCCCTTCTGCTGCTCCCCAGATCCCTAACATTGCCGAAGTGCCAGAGGCAATGCTAGGGCAAGTGCTAGAGGAAAGTCTGTTCCTTTGTCCCATCGAGAACATCTGTTTTCCTGGGTAGCGTAGACAAAATGCTGTACGGTGAGGAATCTGACACTGTGGCGTAGTGGGGACAAAGGTGTCATGTTTGGTGGTGGAGAGGCCTGGTTTGGCTAAAGCTGTGTCTGTTTTTCTGCATGCTTTTGTGTGGATTTATCAGATGACATTCCTGCTGTTTAAATGGCCTTTGTAACTCTGGAGGAATGAGAGGCACTGTCTGTCTCAGTTAACGCCAACTGAGGCAGGCAGGCAGGCAGCCAGCTACAAGCTTAGTCGTGTGTTGCTTTTATTTTGTTCTGCACTGAAGCGCTGAAGTTCTCCTCCCTGTCTTGCTAATAATGACAAATAGTGAAGCTCCCAAGTAGTGTGGTAGGCTACCCAGAACAGACTGACGAAGCTGAATGTGTATGGCTAAATGGTTTGGGAAGACTTCTTTATGATATATAATAGATAAATATAATTTTAAATGGATTACCTTTTTTGGCATATTCCCGCACAGTGAGAGGAGTTGGCACTCCCCATAGTCCCTTAAAGATACATCCCATTCTCTCTATTAAGAGGTTTTCAGTATTTTTAATGAGTGTGTAGATACCTCCTAGTCAAACACAGCTGACTCCTGGGAAGAACTTGCTTTTCAAAATGAAGGGCAAGGGACTGTGGCTATTTCTGAGTCTGAGAATCCATACAATTCCTTCCCTTCCCTCCCCTCCCCTCCCCTCCCCTCCCCTCCACTCAATTCCCTTCGCCTCCCCTCCCCTCCCTTCCCTTCCCTTCCTTCCCATCTCAAAAAAGAGGAGTTTCCTCCCTTCCTCCCTTCCTTCCTCTTTTTTGAGATGGAGTTTCGCTCTTGTTACCCAGGCTAGAGTGCTATGGCGTGATCTCGGTGCACTGCAACCTCTGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTTCCGAGTAGCTAGGATTATAGGTGCACACCACCACAACTGGCTAATTTGTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTTCTGACCTCAGGTGATCCACCTGCCTTGGCCTCCCAAAGTGCTAGGACTTTGAGCCACCACGCCCAGCAATTTCTTTTCCTTCCCCCCCGCCCCTTTTATTTATTTATTTTTAAGACAGAGTCTTGGTCTGTATGTACCCCTTTTTTCACTCTGTTGTCTTAAACATTTTCTTAGGCTGGGCAAGATGGCTCACGCCTGTAATCCCAGCACTCTGGGAGGCCGAGTGGGGAAGCTCGCTTGAGTTCAGGAGTTTGAGACCAGCCTGGGCAACATGTGAAACTCTGTCTCTACAATAAATATAAAAATTAGCCAGGCATGGTGGCACACAGCTGTGGTTCCAGCTACTTGGAGGCTGAGGTGGGAGGATTGCCCGAGCCTGGGAGGTCAAGGCTGCAGCGAGCCATGATTGCGGCACTGCACTGCAGCCCGGGTGACAGAGCAAGACCTCAAAACCTATTTTCTCATTTAGGCCATTCATATCCCTTAGTCTGCTTGAAATAACCCAGCAGCCAATATATCTTCATTATCGGAATCACCCACAGGAAGTCAGCCTTCATGACGTTGTACTTCTGGTAGTCTAGTCAGCCACTGTCTGCAGTCCCTGATCATCTTCTAAGGTTTGTTTGTAAACATGTGGTCTGCAACCAAGAATTTAGGATGTCCAAATATGGCAAGTTTTTGCCCTCTCTGCTATCTAGTAACATGAGTAATAATCTTTGCTCTCCAACACTTTTTATTTGTCCCAACCATTGTCCTAATATTGTAACTGTAATGCAGCAAATTAGTTGCCTGAGTTAAAAGAAAAAAAAAAATCAACCCTTGGCCCTTAAGACGTCTTTTAATACAATGATGTGTTAGTCAACCAAATGATGACCTCAAATGGCTCTGGCCAAGGCCATGTGTGTTGTTTTCCAGCTTTAAAAACCTACTTGCGCGCCTCTTGCCAACCTTCCTCCAGTGTCAAAGTGTCATCTGCAAGGACTGTTGTCTGATTGTTCCTGAGGGTCGTAGGCTTTTGGTGGGATCTTAATTCCATTCTCTTTGATGTCTTTAG
Seq C2 exon
CTGTGAAAATTAAGAAGCCAATCAAGACGAAGTTCAGAATGCCAGTGTTTAACTGGGTTGCTCTGAAGCCCAATCAGATCAATGGCACAGTCTTCAATGAAATTGATGATGAGCGAATTCTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157827-FMNL2:NM_052905:15
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.954 A=NA C2=0.084
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0218118=FH2=PU(10.4=90.5)
Main Inclusion Isoform:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)