HsaINT0065151 @ hg19
Intron Retention
Gene
ENSG00000161791 | FMNL3
Description
formin-like 3 [Source:HGNC Symbol;Acc:23698]
Coordinates
chr12:50045716-50047110:-
Coord C1 exon
chr12:50047009-50047110
Coord A exon
chr12:50045996-50047008
Coord C2 exon
chr12:50045716-50045995
Length
1013 bp
Sequences
Splice sites
5' ss Seq
AAGGTACAA
5' ss Score
6.82
3' ss Seq
TGGTGCTGTCTGCCTGCCAGGAG
3' ss Score
7.66
Exon sequences
Seq C1 exon
CTCACAGAGAAGCTTCTGGACCTAGAGAATGAAAACATGATGCGGGTGGCAGAACTAGAGAAGCAGCTGCTACAGCGGGAGAAGGAACTAGAGAGCATCAAG
Seq A exon
GTACAAGTACTCTGGGGAAGGCAGTCCCTGACTGATCCTGGGCTCCAGCGCCTTGGGGTTCTGCTTTTTTTCCCTGAGTCATATCAAGTTCTCTAGGATTTAGATCTTGATTCACCCTTGAGGTACTCAGGTGTGGGTGGGCTGATGATTTCACCCCATTTTTTTAGTTGGAGAGGAAAGGTGGGGCCAGTGTGAGCCAGACACACACATAAGAGGGTGGGAACAGCTGGGGCACCCACAAGCATTCTGGAGTTCCAACCCAGGCCTCCTCCTACCAGCCCATCCCATTGATTTTTCTCCCCTCTACCCCCGTGTTCCTCCCCCAGCCATGTTTAATGAGCAGGGGCAGAGTGACCAAGTGCTCTGTGTATTAGGATGTCCACCAGGTATCCTAAATTGGCAGGGCAGGTACTCTTCATATTTCATTCTCTTCTGTATTTTCTCCTGACTTTTTGTTCATTATAAAGTCATGCCCCCATCCTACTTTCTCTTTCAGAAGAATATATGCTGGCTCTGTTGAGCTCAATATGTATCTGCCCAGCTTCTGCTGAGCATTGTATTGGGAGCTATGGAGGATACAGAGATGGTTAAGACAGGGTCTTGTTTATAGGGGGCTTCCAATTGAGCCATTATACAAGGCCAAGTGAAATTAAAGCAAAATGAGGCCCAAAGGGTTATGGAGAGAGCCGCTATGTCAGACCGGTGGTAGATTAAGGAGAGTTTCACAGGGGCAACCTTTTTTCCTGGGCTTTGAGGGGCCCATGCAGTGAGAATTGGCTGGAGCAGAGAGGACACTTCAGGGTGCCAGCGGAGGGAGGCAGCTTCTGCTTGCCTCTTTTGTTTTGCTGCCTTCCAGCTTCCTCATTCCCCCACCTGGGTTTCTGCCACTCTGAGCCTCTGAGTACCCTGACAGAGACCCTCGTTAAGAGAACCCTGGGTAGGAATTCTCACTCTTGGGGCAATGACTATGCCTTCAGCCCACTTTTCCCTTAATGGTGCTGTCTGCCTGCCAG
Seq C2 exon
GAGACATATGAGAACACAAGCCACCAGGTGCACACCCTGCGGAGGCTCATTAAAGAGAAGGAGGAGGCCTTTCAGCGTCGATGTCATTTGGAGCCAAATGTCCGGGGCCTGGAGTCTGTGGACAGTGAGGCCCTGGCCAGAGTAGGCCCTGCAGAGCTGAGTGAGGGCATGCCACCCTCCGACCTGGACCTTCTGGCTCCAGCCCCACCCCCTGAGGAGGTCCTGCCTCTTCCTCCACCACCAGCTCCGCCCTTGCCCCCTCCACCTCCCCCATTACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000161791-FMNL3:NM_175736:13
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.382 A=NA C2=0.840
Domain overlap (PFAM):
C1:
PF0636711=Drf_FH3=FE(16.3=100),PF061486=COG2=FE(20.4=100)
A:
NA
C2:
PF0636711=Drf_FH3=PD(19.8=42.6),PF061486=COG2=PD(22.8=39.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGAAAACATGATGCGGGTGGC
R:
CTGGTAATGGGGGAGGTGGAG
Band lengths:
353-1366
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)