HsaINT0083298 @ hg19
Intron Retention
Gene
ENSG00000096433 | ITPR3
Description
inositol 1,4,5-trisphosphate receptor, type 3 [Source:HGNC Symbol;Acc:6182]
Coordinates
chr6:33633612-33635067:+
Coord C1 exon
chr6:33633612-33633753
Coord A exon
chr6:33633754-33634905
Coord C2 exon
chr6:33634906-33635067
Length
1152 bp
Sequences
Splice sites
5' ss Seq
CAGGTGCGT
5' ss Score
9.73
3' ss Seq
CACCCTCTGTATTCCCCCAGGTC
3' ss Score
11.25
Exon sequences
Seq C1 exon
GTTTGTCATCCAGCTGCTGGAAGACCTGGTGTTCTTTGTCAGCGATGTCCCCAACAATGGGCAGAATGTCCTGGACATCATGGTCACTAAGCCCAACCGGGAACGGCAGAAGCTGATGAGGGAGCAGAACATCCTCAAACAG
Seq A exon
GTGCGTGTGCACCCATGAGGGGACGCAGAGGGGCCGGGTGCCCGGGAGAGGGATGCCTTCAACTGCAGGCTCATCCCCCGCTTTAACAAAAATCAGTATATATGGGGCACGACCACGTGCCAGGGACTTCCCTAAGTACCCCACATGTGTTGACGAATTTGATCCTCACTGCCTGGAGGAGGCGCCGTGATTCTTACCCCGTTTTACTGGTGAGGAAGCTGAAACACAGGCCAGAGTCGCTGTCCCAGGGCTCACAGCTAGGAAGCGGCAGCCAGGATTTGAGCTTGTGATGTTGGGTCCAGAGCTGTGCTTCAAAAAATTTTTTTAAAAATTTTTTTATTATGAGAATCATCAAATATTGAGAAAGTATTGGAAGAATAGTACAGGGAACAAGGTGCCTCACTGTTTTGCTGCCTTGGCTTTATGTAGCTCGGTTCACACATCCGTCTTTCCATCCACACATTGCAAAATAGGCAGCATTTTACACCCAAAAGTTTCAGCAGGCATCCCTAACAATAGGGACATTGCCTTACATAACCATAGTACATGATCACACCTAAGAAAATTACAACAATACCAAGTCCATATCACATTTCTCTAATGTTCCCAGAATGTCTTTGTAAAGTTTGTTTTTTTTTTTTTAGAAACGAGGATCCAATTAAGGTTTTTTCATTCCATTCTGTTGCTCTGTCACTTTGGTCTCTGTTTCAGAACAATTTTTCACCTCTCCACCCAGCCCCAGCCTTTAAAACATTTTTGTAATTATGTAACATTTTACTTTGACAAGGCAGGCCTGTGTCTCATCTCTTAAGCTCTGGCCACAGCGGTCCGGCCTGCCTTTTCTCTTAGCCTTAGACCCTGAGCTGCCGAGACCCTCTGCTCCTCCCCCAGGCCCCAGATCTGAGCTGGGATTAGAATCCGCATCAGGGAGGGATAGGCTGGGGTCAGCTTCGGGATTCCAACAAGGAGTAGGGAGAGCTGGGGCTGAGGATGGCTGGGCTGGGGTTGTGGTCCAGCTTAGAATCAGCTCGAAGCTGATGTCCGGGCTGGCTTTAGGGCAGAGTCAGTTGGGACTCAGGGATGACTCCTGGGATGACTTAGGGGTACAGACAGGTGTTGGGGAATCAGTCCTCACCCTCTGTATTCCCCCAG
Seq C2 exon
GTCTTTGGCATTCTGAAGGCCCCGTTCCGTGAGAAGGGGGGTGAAGGTCCCCTGGTGCGGCTGGAGGAGCTGTCAGACCAGAAGAACGCCCCCTACCAGCACATGTTCCGCCTGTGCTACCGCGTGTTGCGGCATTCCCAGGAGGACTACCGCAAGAACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000096433-ITPR3:NM_002224:14
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.083 A=NA C2=0.037
Domain overlap (PFAM):
C1:
PF0136516=RYDR_ITPR=PU(22.2=95.8)
A:
NA
C2:
PF0136516=RYDR_ITPR=FE(25.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCTGCTGGAAGACCTGGT
R:
CTGGTTCTTGCGGTAGTCCTC
Band lengths:
294-1446
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)