HsaINT0088117 @ hg38
Intron Retention
Gene
ENSG00000170759 | KIF5B
Description
kinesin family member 5B [Source:HGNC Symbol;Acc:HGNC:6324]
Coordinates
chr10:32034690-32035667:-
Coord C1 exon
chr10:32035522-32035667
Coord A exon
chr10:32034839-32035521
Coord C2 exon
chr10:32034690-32034838
Length
683 bp
Sequences
Splice sites
5' ss Seq
AAGGTTTGT
5' ss Score
7.81
3' ss Seq
CCTCCAATTACATCTCTTAGGGC
3' ss Score
6.23
Exon sequences
Seq C1 exon
ACATATGTTCCATATCGAGATAGTAAAATGACAAGAATCCTTCAAGATTCATTAGGTGGCAACTGTAGAACCACTATTGTAATTTGCTGCTCTCCATCATCATACAATGAGTCTGAAACAAAATCTACACTCTTATTTGGCCAAAG
Seq A exon
GTTTGTTGTTAAGAAAGTACAAAACCTAAATTTAGATAGACCTTTTGTTTATAAAATGTAGGAAAATGTGAGCTGTTATTCCAACCTGTACATACTGTTTTGTGCTAGACACACTCAGTTTGAATTGATGACAGATAATACAAGGTGGGTCTGATTTTTAGACTGCTTGGTTTAAGTTTTAGTACACATTAAAGTCAGATGTAATTTTAGTCAAATTTGTGTGACAAGCTGTAATTTGGTATTAAAGAAAATAAGCATTTGAATCAAATAATGAGGTCAAAGCCTGGCAAACATAATCCTCTGTTAAGCCTGTAGACATGCATGACAGGTTAATATAATCTGTATGAGATGATTAGGAAAATCAGTAATGATGATTCCGTCTTTGACTTTCAACAGTAATTTCTTAATTCAGCCTTGCAAACAAATTGGAAAAATATAGGCCTTTGTCTTTTATTTTTAGTGGTTTGTTGATTTTTTTTTTTTTAAAGCTATTCACAGATTTTGGAGCAGACTCAAATTTAGTTGAGTTGTAAATAACGTCATATGTTGCGGCTTTTAGTATTTAGTCTAAGAGATTACTGGACAAGCATAAGTTTCTTAGCCATATATACATATATTCCATATAGATAAAATTAAAAATAATTTCAGTCTCATCCTTTTTTTCCTCCAATTACATCTCTTAG
Seq C2 exon
GGCCAAAACAATTAAGAACACAGTTTGTGTCAATGTGGAGTTAACTGCAGAACAGTGGAAAAAGAAGTATGAAAAAGAAAAAGAAAAAAATAAGATCCTGCGGAACACTATTCAGTGGCTTGAAAATGAGCTCAACAGATGGCGTAATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000170759:ENST00000302418:10
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0022518=Kinesin=FE(15.4=100)
A:
NA
C2:
PF0022518=Kinesin=PD(1.3=7.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCGAGATAGTAAAATGACAAGAATCC
R:
TTACGCCATCTGTTGAGCTCA
Band lengths:
279-962
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development