HsaINT0099917 @ hg19
Intron Retention
Gene
ENSG00000136536 | MARCH7
Description
membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:17393]
Coordinates
chr2:160619391-160621185:+
Coord C1 exon
chr2:160619391-160619504
Coord A exon
chr2:160619505-160621136
Coord C2 exon
chr2:160621137-160621185
Length
1632 bp
Sequences
Splice sites
5' ss Seq
CGAGTAAGT
5' ss Score
10.15
3' ss Seq
TCTTTCTGCATTGTTTCTAGTTT
3' ss Score
7.85
Exon sequences
Seq C1 exon
GCTGAGTATGAGTTTATCAGCTCTGGTCTCTACCTAGTGGTGTTATTGCACTTGTGCGAACAAAGCTTTTCTGATATGATGGGAAATACAAATGAACCAAGCACACGTGTCCGA
Seq A exon
GTAAGTAATAATGAAGTTGGGGAGAGGGAGGGTATGATGCAGCAAGTGTATGCCTTGGAAAGCAGATTGTTTCATATGTTGACATCTTATTTCCTTTGGGAAGCTTTTATTTTTTAAATGTTTCTTAAAAATAAAGATACCGTAGATTTAATGGAAATTGCTGTCTTCTATAACAAGCAGCCTGATTTTCTCATAAAGTTATTTTAGAGAAAGAAGTAATTTTCTAGCTCTCAAAGGTAATTGGAATGTATTTCATTGAAAAACAGAATTGGAAACATCGAGGGAAAATGGGCTTTTTATTATTAAAACAAAACCTCAGTATTATCACTTAGAAACCTGAAATTGAACTCCAAAAGCCAAAGAGTATGGGAAATTAACTTCAATTTATTTGTTACTGTTCTACAAAAGATTACCAGTGTACTAATTTTTAAGTGTCCATATTACAAAGTATTTTAGATATGGAATAGTTGGTTGTTTACTGTGTGTGCTATTAGCCATAATACAACATTTTGGCCAGCTGTATGTTAGGTATTTATAAGTAAATGATGCTCTTTGTGTCAGTGTACCAGAGGAAACTTTATGCTTTGCTGTCTGGGCCATTTTGTGTAGCAAGGGCTAGGGTCTCTATGTATCTGCCATTATTGTAGCATTCTGAACACTTCATGTCTTGAAATGTGTTCATAAGTATATCCTTCAAACTTTCTTACATGTTAACTTCGGTGATAAAAGTGTAGTAGAGTTCATGTAATGTTTTTATTTTGAAAATTATCAAATAACTGCAATTCAATGTATGTAATACTCCTTCTAAATTAGTAAAAAATTTTTCTTTATTTTATCATGTGGACATTATTCCAGTGAGCTGGTTAACAGATAATTACCATTGAAGAGCATTCATATTATCTATCAAGAGCATTCAGAATTTGAGCAAAGATCTCTTGACTTCTAAGTACTTTACAAATTGTGAGCCCCTAAAACCTTAATACCGTAAAATGATTTCTAAAAAGGTACCTTAAGTCTTCAGGATGAATAAACCATATAAAACATTTAAGAACTTCTGAATTCATGTGTTTTTAAAAGTTCATATTAACAAGTTTTACAGTGGAAAATTACAGAATTTTGGATGATACTCCAAAGTGGAAGTCATTAGGATTTTTTTTAATGTATAGAACTGTATACTTTTATCAAATTTAGGTAGGAAAATATTGGTTCTTGGGAGTTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGCGCGCCCACTGAAACTGAATTTATTTGGGTCCAAATACAAGGGTGGTTTTTTGTTTTTTGTTTTTTTTCCTCCATTTCGTAATTTTTTGAAGTGTTTATAAGAAGACAATATCATTGGATAAAATTATTGTATCTGCTCCCAATTTTAAAAAACTGGTTTCTACATGATTATAAAGATTATATAAAACATTTAAAAATTAATGCCATTAAGCTTGTGATTTTTGATGTTAGGGGGAGAAAAACCCCTATTTAAAGGCTTAAACTGATGTTTGACTTTTTAAGTAGAAATGAATCTCCTATACTGATTCTCTCTTTAGATCCATTTGCAACATTTAAACTACTGTATTTCTTTCTGCATTGTTTCTAG
Seq C2 exon
TTTATTAACCTTGCAAGAACTCTTCAGGCACATATGGAAGATCTCGAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136536-MARCH7:NM_022826:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.046 A=NA C2=0.294
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)