HsaINT0101780 @ hg38
Intron Retention
Gene
ENSG00000145794 | MEGF10
Description
multiple EGF like domains 10 [Source:HGNC Symbol;Acc:HGNC:29634]
Coordinates
chr5:127447557-127449222:+
Coord C1 exon
chr5:127447557-127447684
Coord A exon
chr5:127447685-127449098
Coord C2 exon
chr5:127449099-127449222
Length
1414 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGA
5' ss Score
8.68
3' ss Seq
GTTGTTTATATTTTTAACAGTCA
3' ss Score
6.07
Exon sequences
Seq C1 exon
GAACCCTTCCTCACAGCAATGGTGGAAACGCTAATAGCCACTACTTCACCAATCCCAGTTACCACACGCTCACCCAGTGTGCCACATCCCCTCACGTCAACAACAGGGACAGGATGACTGTCACGAAG
Seq A exon
GTGAGAGGAATTGGTTCAAGTCTTTGGAAGTGGGCTGGGGAGAGAGGAAGGGAACCAGCATTTATTGAGGGCCGCTGTTCACCAGAGGCTGTTCTAGGTACTTTACATATATTATCTAATTTATTCCTCTAAACAGTCCTCTGAGTGTGCTTTGGGAATCTCAAGTTTACTGATGAAAACCTGAGTAGTAGGGAGTTTAAGTTACTTCCAGACATAGCTGCCCGATAATGAGTGAGGCAGCTGCTGTGTGAGTCAAAGTCTCTCTGTCTCTACAATCTGTACTGTTTCCATTACACCGCTTTAGAAAAACGTTTCTAATTTTACATGAGATTTTAAAATAATGACTCATAATGACATTAACAAAAACATAAAGACCTATAGCAGAATCAGCCGTGGGCAAAATCTCCAAGTGTGTCTCTTCTGACCGCCCGTCCTCCAGTACCCGTTCCTGGCCACCTGTGCTTTAGTAACAACAACAGTAATAGGCACTGATTTGGGTTGAACCACATGAAATTGCTATTTTTGTAGGTCAACAGTGGTCACATAGCAACAACCTAATATTATGTGCCAAGCATTTCTAATCACTTAAAAATATAAACTCATTTAATCTTCACACCAGTCCTATAAATCAAGAGTGATTATTATGCCGATTTTACAGATGAGGAAACTGAGTCACAGAGAGGTTGGAGACAGAGTGTCTAGAACCCAGAGCTGCTACTCCAATAGCACCCAACTCACCCCAGGTCTTCCCCACAATGCTCTGAAGTCTCAAACATTTCTTTCTTCCAGTCATACCCAAATTATATTTCTAATCTCTGTTGTCTAATTCCAGTGCTCTATTAGAAAAAAAATCAAGCTAATTAAGTTAATCCAGTTGTAATTTAATTAATGCAGCTATAGATTTTAATTATAGTGCTTCATGGTTAAATATCACTCCACATACCCCAGAGACTTTCACATTCATCAATTTATTCTCATACAAATTCAGGGAAGGAGGCAAAGCAGATAATCTTATCCTCATGTTTACGCCTAGGATAACTGCTAAGAGTCACCTGTGATTCACACAAACATACAATTTTTGATGGAAGAACTTAGACCAAGAGTTCTTTTTTTTTTTTTTTTTCCAAATCAAAGTTACATGTGTATAAATCCAAATAAGGTCTAATTGGCACAGGATGACAGAGTGAAATGAAGATCTTGAGGTGGTGGAGGGAGTAGCTAGGACTGAAGGACATGAACTCCTGCCAGCTTGCAAGTCCCACCAGGTTACAAGCAGTCACCTCGGCCCCTGAGCTCAGGTCACTCTAAGGACTGGTCCTCAATATGTGCCCTGGACTTTTCCCCAGGTCCATAACGCTGTGCTGTGCCGCATTGTATTTTGTTTTTAATCTTTCGTTGTTTATATTTTTAACAG
Seq C2 exon
TCAAAAAACAATCAACTGTTTGTGAATCTTAAAAATGTGAACCCTGGGAAGAGAGGCCCTGTGGGGGACTGCACTGGGACATTGCCGGCTGACTGGAAACATGGCGGCTACCTCAACGAGCTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145794:ENST00000274473:22
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.349 A=NA C2=0.286
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACCCTTCCTCACAGCAATGG
R:
CTCGTTGAGGTAGCCGCCAT
Band lengths:
247-1661
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development