HsaINT0101788 @ hg38
Intron Retention
Gene
ENSG00000145794 | MEGF10
Description
multiple EGF like domains 10 [Source:HGNC Symbol;Acc:HGNC:29634]
Coordinates
chr5:127396532-127398796:+
Coord C1 exon
chr5:127396532-127396778
Coord A exon
chr5:127396779-127398675
Coord C2 exon
chr5:127398676-127398796
Length
1897 bp
Sequences
Splice sites
5' ss Seq
CTTGTAAGT
5' ss Score
8
3' ss Seq
GTCACATGTTAATCCCTCAGCTG
3' ss Score
5.38
Exon sequences
Seq C1 exon
CCTGCGATGGTGATCACTGGGGTCCCCACTGCACCAGCCGGTGCCAGTGCAAAAATGGGGCTCTGTGCAACCCCATCACCGGGGCTTGCCACTGTGCTGCGGGCTTCCGGGGCTGGCGCTGCGAGGACCGCTGTGAGCAGGGCACCTATGGTAACGACTGTCATCAGAGATGCCAGTGCCAGAATGGAGCCACCTGCGACCACGTCACGGGGGAATGCCGCTGCCCACCAGGATACACCGGAGCCTT
Seq A exon
GTAAGTCACATGCTGCCCAGCAGCAGAGCAGAGCCCACCCACCCTCTCCATTCATGCTGCTGCTGCCATCATATTTCTTGTGCCTCAGTTTGCATTGCTGCCTGAAGAGTTACTGATGGGTCTAGGCTGCAGGCACAGTTATAGAGGTCAGCAGTGATGGCCACTAGGTGCTGCTGCTGTTTGGCCCTTGCACATCAGATCCCAGCCTGAATCTAAGGGTCAGCTTCCATGCTTTCCTTCTAGCAGGCAAAGAGAGAGAGGGTCAGTCAGGATGTTGTGTTGAATGGCACTATTTGGGGGTTGTTGGGGCATATTTGGGATTCTGTTTGGATCTCCCGAGAATATGTTCATTTATACTGCTGGTTGTTAATGGTCCATGTCTTTTTGCTCTTTGTGGCAATTAATTAGCTGGGGAAAGCTGGGTGGGTTCAGTGCATTAGAAGAGAAAAGGAGGAAGGTGTTAAAAATAATCCATAATAAAAGATTAACTCTTAGGGATACATACATTATTTAATGCTCATGGATACATATTGCTTTGTGAATGTGAAGATATATGTATTACATCTATGTAGATTTTGTGCACACACATAGTTTAATTCTTTCTGAGGAACATTCAAGCAACTACTTAACCTCCACTGTCTTTATTTTGTTGGAAGGGCATTCTTCAGTTCACTTCTATTCACCAACAGAATTAAGAGGCAGAAGTTGCTAAAAAAAAGTAAGAGATAGAAAAATCCTCTTCCCTTACTGAGAAAATTACATTTATAAATCAAAGAACTAAAACTTGAAAAAACAAAATGTGGCTGATTAGGTAAACACTTCCTGCCAACAGTGTTAAACGCCTGTAGAGTGGAGCTAAAGAAAAAAATTGCATTAGCCTAGAAAGCCCTGATTTTCAGAATTGATGATTATCTCAAACTGTTTAATTGTTAATATTGCTTTTATGGGTTTTCATCAAGACCACAATTGAACTGGGCTGTGGGAAACTTGGAGCAATTTCCCAGGAGAGCAGGAAAGACAAAGGCTTAAAGAAGAAGGGCCATGCGACACGTGGGTGGGTGAGGGAAGGGAAACTTGTCAGTCAGTAGGAGAGAACACCAAAAATGGATGATGAGAAGGAGTTCATGTCCTTTGCAGGGACATGGATGAAACTGGAAGCCATCATTCTCAGCAAACTAACACAGGAACAGAAAACCAAACACCGCATGTTCTCACTCATAAGTGGGAGTTGAACAATGAGAACACATGGACACAGGGAGGGGAGCATCACACACTGGGGTCTGTCTGGGGGTGGGGGGAAAGGGGAGGGAGAGCATTAGGACAAATACCTAATGCATGCGGGGCTTAAAACCTAGATGACAGGTTGATAGGTGCAGCAAACCGCCATGGCACATGTACACCTATGTAACAAACCTGCATATTCTGCACATGTATCCTGGAACTTAAAGTAAAATTTTAAAAATTAAAAAAAAAAGGATGATGAATATGTGCACAAAGGGTGTGATGTGCAACATCTCAATTTTCTTTGGGAACAGAACAAACATATAAACAAAAGTAGACTTAAACTGGAGCACAAGCGCTTTATAAGTGTTACATGAGAAGTTCCTGTCATCAATGAGTGTTTGGCCAGTTTTCTTCCTCAGTGTTCTCAGATAGGATAGCTTCTCTTCAAACCGAAATGGCTTTATTAGAAAGTACCCCAAAACAAAGGGAAGGACTGGGTGACTCCTCAAAGACACTTCCAGGCAATATGATTAATGTTCTTGATGTTAATTAATTAAATGAACAATTATTGAACACAGAAAGCTTGTCTATTTTGGGGACCCTGGGTACAGTGAACCCGAGGGTCATGTGTCTGGGAAATAACAGTGTCCTTTGTCACATGTTAATCCCTCAG
Seq C2 exon
CTGTGAGGATCTTTGTCCTCCTGGTAAACATGGTCCACAGTGTGAGCAGAGATGCCCTTGTCAAAATGGAGGAGTGTGTCATCACGTCACTGGAGAATGCTCTTGCCCTTCTGGCTGGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145794:ENST00000274473:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF126612=hEGF=PU(84.6=13.3)
A:
NA
C2:
PF126612=hEGF=PD(7.7=2.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCGATGGTGATCACTGGG
R:
GGGCAAGAGCATTCTCCAGTG
Band lengths:
354-2251
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development