HsaINT0101809 @ hg38
Intron Retention
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF like domains 11 [Source:HGNC Symbol;Acc:HGNC:29635]
Coordinates
chr15:65980778-65982488:-
Coord C1 exon
chr15:65982242-65982488
Coord A exon
chr15:65980899-65982241
Coord C2 exon
chr15:65980778-65980898
Length
1343 bp
Sequences
Splice sites
5' ss Seq
CTAGTGAGT
5' ss Score
7.43
3' ss Seq
ACCTCTGCTTCTCCATGCAGCTG
3' ss Score
11.47
Exon sequences
Seq C1 exon
GCTGCGACAGCGACCACTGGGGGCCCCACTGCAGCAACCGGTGCCAGTGCCAGAACGGCGCCCTGTGTAACCCCATCACAGGCGCCTGCGTGTGCGCCGCCGGCTTCCGTGGATGGCGCTGCGAGGAGCTCTGCGCACCTGGCACCCACGGCAAGGGATGCCAGCTGCCGTGCCAGTGCCGACACGGTGCCAGCTGCGACCCCCGCGCCGGCGAGTGCCTCTGCGCACCTGGCTACACCGGCGTCTA
Seq A exon
GTGAGTCATGCGGCAGGACCTGGAGGGGCGGGACCTGGAGGGGCGGGACCTGGAGGGTGCCTGGGTGGGGAGGGTAGAGGAGGTGGAGGGGCTGGGGCGGGGCCTGGAGTGGCTGCCCTCACCGCAGCTGCACGCCCAGCCCTGGGCTCCTTGTGGGTGGGCTGGGTGGTGGGACCAGGAGGGATAGTCTTGGCTGTGAAATCTCCTGTGAGTCTAAATGCCCAGGCCTCACCCACGCAGGTCTCAGATTCCTTCCTTCCAGGACCGCGTTGACTGGTCCTTCCTGAGACTGCCCGAGTGGGCACTCCCTAAAACCCTCCCAGGAGGCCCTTCCTGGCAGAGACAGCCCTTATCTTGAAAGTCTCTTCTGACCTTACCCAAATGATGCTGCTCACCTGGGGCCTTCCCTTCTAGGGCATTTGGGACAGAGAGAGGTGAGGGTCCTAGGCAGATACCATGTACAGATTTGGGAGGATTACTCTGCCTGTTCCTCTCCCCTACTTTCTCTCCCCAGACACCAAACAGCCCCTCATTCCAGTTCCCCAGAGAGTAGTATTGACAGGAGACCTACAAGACTGCTTAGCTGAGACCCCCTCAGAGGCAAGATTGAAGTTCTCCTCCCAACCCTGTAGCAGACTCTGTGGCCTCTCCAACAGCCTAGATCCTGAGGGGTGGCCAAGGACTCTGACCACAGAGACGTTGTTGATTGAGGGTGTTCCCTACCCCGATGTCTGGCCAGCTCCCAAGTCCTAGTGAGCTAGAGGCCAGGGCCATTGGATGAAGGCCCAAGACCAAGACCCCATGCAAATCCTGCCCCACCCTTCAACAGCACCCAGTCCCTGCAAATGAGCCTGTCATGGGAGCTGGGAGCCTTCCTGAGCCTGGAAGGAACGTGCTCCAGATTCTTCCCCTCTCTGAATCTAGGTGGATTCTTAAAGATGGGATCCATGAGCACTTCTCAGTGCCTTCATTAATGCAATGACTTTGGCCTGGCATGCCCTTCCTTCCATTCTCCTGGTTAAATTAACTTCACCTTTAAGGCCCAAGTAAAATGCCTTCCTCCTTGGGAAGCCTTCCTCAGCCTCCTCCCCAGAATACTCTTCTGTACACTAAGAACACTTAAGTCATCCCACAAGTATTGGCCCAAGCACCCTACATTCCAATGTATTCAGTCTGAGCCTTGCTTCCCCCTCCTGGCAGGGAGCAGGACTGCAGTTCAGCGGATGCTGTGCCTAATACAGATCCATTAACTGCGGAGGAATTCCTAGGGAACCCTGGAGCACTGGGGCCCTGCCACCTGATCTGAATGCTGCTGTGTCTAACACCTCTGCTTCTCCATGCAG
Seq C2 exon
CTGCGAGGAGCTGTGCCCTCCTGGGAGCCATGGAGCTCACTGTGAGCTGCGCTGCCCCTGTCAGAATGGGGGCACCTGCCACCACATCACTGGCGAGTGTGCCTGCCCCCCAGGCTGGACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890:ENST00000409699:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.011 A=NA C2=0.038
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PU(58.1=30.1)
A:
NA
C2:
PF0005319=Laminin_EGF=PD(39.5=41.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACAGCGACCACTGGGGG
R:
CAGTGATGTGGTGGCAGGTG
Band lengths:
334-1677
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development