RnoINT0091349 @ rn6
Intron Retention
Gene
ENSRNOG00000010634 | Megf11
Description
multiple EGF-like-domains 11 [Source:RGD Symbol;Acc:1582797]
Coordinates
chr8:70112923-70114800:+
Coord C1 exon
chr8:70112923-70113169
Coord A exon
chr8:70113170-70114679
Coord C2 exon
chr8:70114680-70114800
Length
1510 bp
Sequences
Splice sites
5' ss Seq
TTAGTGAGT
5' ss Score
5.79
3' ss Seq
CGCTGTTCCTCTCGCTGCAGCTG
3' ss Score
9.61
Exon sequences
Seq C1 exon
GCTGTGACAGCGAGCACTGGGGTCCCCACTGCAGCAACCGGTGTCAGTGTCAGAACGGCGCCTTGTGCAACCCTATCACCGGCGCCTGCGTATGCGCCCCCGGCTTCCGAGGCTGGCGCTGTGAGGAATTCTGCGCGCCCGGTACTCACGGCAAGGGCTGCCAGCTGCTCTGTCAGTGCCACCACGGCGCTAGCTGCGACCCGCGCACTGGCGAGTGCCTCTGCGCACCAGGCTACACCGGCGTTTA
Seq A exon
GTGAGTAGAGAGGGAGTGGCCTGGGGTGGGGCCAGGGCGAGGTCAGGACTCCTGGGGTGGGGAAAGAGGGGAAGGGGCAGAGCCAGGAGACAATGCCGGTTGCCAGGCTAAGGGCCTGGAGAGCGTGGTCTAAATGAGCCTGGCTTGTAGCTGGACAGGGCTGGGGCAACTTCTTAGCACCCTAGTGGGCAGGAAGAGCAGAATGTCCTGGTTGTGACATAAGCCCTCTGACCTCAAGTGCAGCAGTTTCTTTAAGTACCCAGGCCTTACCCACACAAGTCTCAGATCCAAGCGCAGAAGTACCCGGTCCTACTGGAGACAAGTCACATGGCTCGAAAGGTCCTTCCTACTTAGGGGACACAAGTGAGTTTGGCCTCCTCTTTAGATCTTCGTAGTGTGCCTACTTGCCCCATTCTAATTGAAACATCTGAGCTGTAGGGCTGGTATGAGCCCATCTGATGTATCATGTGCAGAGTGGCTGCTCACTTCTGTGCCCTGGGGAAGCCATACTGATAGGGATTCCCCAGGACAGTTTAATTGACATTGGCAGAGAGACTGGTGTCCTTCCAGTCTAGCTGAGGTTCTACACATTCTCTTAGATCCCAAGCAGAAGCCAAGGACGCTGACCACAAGACATCCCAGATTGACAGCCTCTCCTGCCCCAGTGTCTGATCAGCTCCCAGGAAGCCATGGTCATTGGAGCGAGACTCAAGGCAATGACTCAGACCTTCCCTATGCTCCCACAGAGGTCGGTCTCCACACATGGCAGCTGGAGCTCTTCAGAGCCTAGGAAAGACGATCCTTGGGGTTTCCAGCTTCTCTCTTTGAAAACGGGCAGGTTTTCAGAGGCTGGAGAAAGGGCTCAGCAGTGTAGAGCACTGGCTACCCTTCCAGGGCTCCTGAGTTCAACTCCCAGCAACCACAGGGCAGCTCACAACCATCCTATAATAGGATCTGATGTCCTTTTCCGACATCTGTAGGTATATATGCAGAGAGAGCACTCATACACATAAAATACATAAATTTAAAAAAAATCTTTAAAAGAGAGGAGGAGAAATAGGCAAGATTTAAAAAGCCAAATCCATGGCCACATCTTAGCTCCGTTGCTCGTGCTTTTTCATCCATCTGGCGTGCCCTTCCACCCTCTCCGTGCAATCGGCTTCACCTTCAAGCCTAAGTAAACCATCTTCTTCCTCGGGAAGTCTCTTTGGCCTCCTCCCCAGAACCTTCAAGTGCTGGCCCAAGTGCCCTACAATTCAATACATTATATCTGTCTCCCCCTACTGGCGGGGATCAGAACATCCATGCTTAAGATGGTGGGGAGGGGCTTCAGACACTCAAGTCCGCAGGTGGGCTGATTGCTGACGTCATCCACACCTGTGGTGGGGGAGGAGCCTGGGCTGAGACTGTTCTCGAGACTGGGCTCACTAGGGCGTTCTGCGGCATTGGGACTGAGCACTAAGGGCGCTATTGGGAATTCTGCTGTATGACGCTGTTCCTCTCGCTGCAG
Seq C2 exon
CTGTGAGGAGCTGTGCCCCCCTGGGAGCCATGGAGCTCACTGTGAGCTACGCTGCCCCTGCCAGAACGGAGGCACCTGCCACCACATCACTGGCGAGTGTGCCTGTCCTCCAGGCTGGACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000010634:ENSRNOT00000037941:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.052 A=NA C2=0.044
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=WD(100=54.2),PF0005319=Laminin_EGF=PU(54.3=30.1)
A:
NA
C2:
PF0005319=Laminin_EGF=PD(43.5=48.8),PF126612=hEGF=PU(61.5=19.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGTGACAGCGAGCACTGG
R:
CTCGCCAGTGATGTGGTGG
Band lengths:
343-1853
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]