HsaINT0101815 @ hg38
Intron Retention
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF like domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr1:3509075-3509992:-
Coord C1 exon
chr1:3509870-3509992
Coord A exon
chr1:3509246-3509869
Coord C2 exon
chr1:3509075-3509245
Length
624 bp
Sequences
Splice sites
5' ss Seq
GCCGTGAGT
5' ss Score
8.56
3' ss Seq
CGCCTCTGTGCCCCTGGCAGCCC
3' ss Score
7.49
Exon sequences
Seq C1 exon
ATGTGGATGAGTGCGCCTCCAGCCGTGGCGGCTGCGAGCACCACTGCACCAACCTGGCCGGCTCCTTCCAGTGCTCCTGCGAGGCCGGCTACCGGCTGCACGAGGACCGTAGGGGCTGCAGCC
Seq A exon
GTGAGTCTCCCGCCCTCCGCGGAGCACCGGCCTCTGCCTTCTCGAGTTTGCCCCAGCTGACCCTGCGTCCCGCAGGCCTGGCCCACCCCACCCCCACCTGCCTGGGGTCCTTTGCCCCCTGGCCTCTCTGGGCCAACACACCTCAGAGGCTCTTGGGCCCTTGGGGACCCACTGAGGTCCTGCCTCTTCTGAGGGCCGTGTGGGGGTTGGGGACAGTGGGGTGGGGGAAGCTGGTGAGACAGGCATCCTCCCGGAGCCCAGCACCTGTCCTGACCACGTGAGAGAAGGGACCAAGACCTAAGGTGATGTTGTCCCTGGGACTGATGGCAGCTGCTCCCACCCCTACCCCTCTAGGCCCCAGAGTCCCTAGAGTTGGGATGAGGCTGGGGGCAGAGGGGCCGGGTTCAGGTCCTCAGGGCCCAGAGCCTTCTCTTTCCTGAGAAGGAGGGTCGGGTGCAGCTGGGATGACCCCTGGGACCAGGCTGAGGAGGTGGGGGTAGTGGAGGCAGTAGGAGGGTGGTGGGGTTCCCTGGGGTGGGGCTTAGGCCCAGCCCTACCCGCCGGGGGGTCGCTGGAGCAGGCAGGTGGGTGGCAGGGGCTAAGGCGCCTCTGTGCCCCTGGCAG
Seq C2 exon
CCCTGGAGGAGCCGATGGTGGACCTGGACGGCGAGCTGCCTTTCGTGCGGCCCCTGCCCCACATTGCCGTGCTCCAGGACGAGCTGCCGCAACTCTTCCAGGATGACGACGTCGGGGCCGATGAGGAAGAGGCAGAGTTGCGGGGCGAACACACGCTCACAGAGAAGTTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591:ENST00000294599:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.297
Domain overlap (PFAM):
C1:
PF146701=FXa_inhibition=WD(100=85.7)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGTGGATGAGTGCGCCTCC
R:
CAAACTTCTCTGTGAGCGTGTG
Band lengths:
294-918
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development