HsaINT0101847 @ hg38
Intron Retention
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF like domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr1:3511550-3512128:-
Coord C1 exon
chr1:3512006-3512128
Coord A exon
chr1:3511688-3512005
Coord C2 exon
chr1:3511550-3511687
Length
318 bp
Sequences
Splice sites
5' ss Seq
ACCGTGAGT
5' ss Score
9.4
3' ss Seq
GGTGGCTGGTCTCACGGCAGGGA
3' ss Score
4.95
Exon sequences
Seq C1 exon
ATGTGGACGAATGTGCCGCAGGGCTGGCCCAGTGTGCCCATGGCTGCCTCAACACCCAGGGGTCCTTCAAGTGCGTGTGTCACGCGGGCTATGAGCTGGGCGCCGATGGCCGGCAGTGCTACC
Seq A exon
GTGAGTGGGCAGCCGGCAACAGGCTGAAGGTGCCCGGGATGGCCATGCTGCTCCCCAGGACCCCGAGGCCTGCTTTGGCTGAAGGGCAGGGCTTCCTTGTCAATCAGGGGCAGCCCTGGGTGTGAGCCCTTGGTGAGCAGAGGGTCGAGGGAGAGCAGGGGGTCCCAGACCCAACAAGGCCTGGGAGCTCCATGTTGCTGCTTCCCACGGGTGTCCCCAGGCCCGAGGCTGGCTGCTGGGTGGAGGTAGGGGTAACTAAGGTAGGTGGGGGTCATCCTAGCCGCCATCCCATACCCTGGGTGGCTGGTCTCACGGCAG
Seq C2 exon
GGATTGAGATGGAAATCGTGAACAGCTGTGAGGCCAACAACGGCGGCTGCTCCCATGGCTGCAGCCACACCAGTGCTGGGCCCCTGTGCACATGTCCCCGCGGCTACGAGCTGGACACAGATCAGAGGACCTGCATCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591:ENST00000294599:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=WD(100=95.2)
A:
NA
C2:
PF146701=FXa_inhibition=WD(100=76.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGTGGACGAATGTGCCGC
R:
AGGTCCTCTGATCTGTGTCCA
Band lengths:
255-573
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development